ISCHEMIC STROKE
Clinical trials for ISCHEMIC STROKE explained in plain language.
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New drug tested to clear remaining blockages after stroke surgery
Disease control CompletedThis study tested whether adding the medication dornase alfa (Pulmozyme) after mechanical clot removal could help restore better blood flow to the brain in stroke patients. The trial involved 39 people who had an ischemic stroke, received clot-busting medication, and were eligibl…
Matched conditions: ISCHEMIC STROKE
Phase: PHASE2 • Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Disease control
Last updated Apr 02, 2026 00:57 UTC
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New device aims to pull clots from stroke Victims' brains
Disease control CompletedThis study tested a medical device designed to physically remove blood clots from the brain during an acute ischemic stroke. It involved 8 adult patients who had a severe stroke and could be treated within 8 hours of symptoms starting. The main goal was to check if the device was…
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: Jacobs institute • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New stroke drug tested to prevent worsening and recurrence
Disease control CompletedThis study tested whether a medication called Renexin CR could help people who recently had a stroke caused by a blood clot (not from the heart). It aimed to see if the drug could prevent the stroke from getting worse in the hospital and prevent another stroke within 90 days. The…
Matched conditions: ISCHEMIC STROKE
Phase: PHASE4 • Sponsor: SK Chemicals Co., Ltd. • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New hope for stroke recovery? drug aims to reduce lasting disability
Disease control CompletedThis study tested whether a drug called Mexidol®, when added to standard treatment, could help people recover better after an ischemic stroke. Over 300 patients who had recently suffered a stroke were given either the drug or a placebo for about 10 weeks. Researchers measured if …
Matched conditions: ISCHEMIC STROKE
Phase: PHASE3 • Sponsor: Pharmasoft • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Breakthrough stroke trial tests 'Second Shot' drug to clear stubborn clots
Disease control CompletedThis trial tested whether giving a clot-busting drug directly into a brain artery could improve blood flow for stroke patients when the initial mechanical clot removal was only partially successful. It involved 156 adults across 20 European hospitals who had a stroke caused by a …
Matched conditions: ISCHEMIC STROKE
Phase: PHASE3 • Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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Zapping the brain to regain movement after stroke
Disease control CompletedThis study tested whether applying gentle electrical stimulation to the brain, along with standard physical therapy, could help people recover movement and thinking skills after a stroke. It involved 60 stroke survivors who were between two weeks and two years past their stroke. …
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: Mahidol University • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New program helps stroke survivors breathe easier during recovery
Disease control CompletedThis study tested ways to help stroke patients consistently use their sleep apnea breathing machines during rehabilitation. Researchers worked with 36 stroke survivors who had breathing problems during sleep, providing coaching, technical support, and follow-up calls to encourage…
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: University of Washington • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Leg cuff therapy tested to fight repeat strokes
Disease control CompletedThis study tested whether a therapy using leg cuffs could help people who recently had a stroke or mini-stroke caused by a severe blockage in a major brain artery. The therapy, called Enhanced External Counterpulsation (EECP), gently squeezes the legs to boost blood flow. Researc…
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: National University of Singapore • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Mind-Controlled therapy helps stroke survivors walk again
Disease control CompletedThis study tested a new rehabilitation therapy for people who have difficulty walking after a stroke. It combined a brain-computer interface, which reads brain signals, with functional electrical stimulation, which activates leg muscles. The goal was to see if this high-tech ther…
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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First human test: cord stem cells injected to help stroke patients heal
Disease control CompletedThis small, early-stage study aimed to see if a single infusion of stem cells from umbilical cords is safe for people recovering from a stroke. It involved 18 patients who were 3 to 6 months past their stroke. Researchers gave the infusion and then closely monitored participants …
Matched conditions: ISCHEMIC STROKE
Phase: PHASE1 • Sponsor: Shanghai IxCell Biotechnology Co., LTD • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Could lying Head-Down boost stroke recovery?
Disease control CompletedThis study tested whether having patients lie with their head lowered after a successful procedure to remove a stroke-causing blood clot could improve recovery. It involved 90 people who had a major stroke and whose clot was successfully removed. Researchers compared standard car…
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: General Hospital of Shenyang Military Region • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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Zap and step: can brain stimulation supercharge stroke rehab?
Disease control CompletedThis study tested whether a combination of gentle brain stimulation and challenging balance exercises could help people recover after a stroke. Thirty stroke survivors were assigned to different groups to compare the effects of brain stimulation, exercises, or both together. The …
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: University of Phayao • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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Brain-Boosting drink tested for stroke recovery
Disease control CompletedThis small pilot study tested whether adding a daily nutritional supplement drink to standard stroke care is practical and acceptable for patients. It involved 24 adults who had recently suffered an ischemic stroke. The main goal was to see if patients could stick to the regimen …
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: Barts & The London NHS Trust • Aim: Disease control
Last updated Mar 12, 2026 13:51 UTC
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Text messages and health workers team up to fight heart disease in india
Disease control CompletedThis study tested a new support program to help people in India better manage existing heart disease or stroke. The program combined non-doctor health workers, healthy lifestyle text messages, and a computer tool to guide treatment. Researchers wanted to see if this approach impr…
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: Public Health Foundation of India • Aim: Disease control
Last updated Mar 06, 2026 15:38 UTC
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New brain scan could predict future strokes after surgery
Diagnosis CompletedThis study tested whether a detailed MRI scan of brain artery walls could help predict which patients are at risk of having another stroke after a procedure to open a narrowed artery. Researchers followed 74 patients who had a stroke or mini-stroke and a severe artery blockage, a…
Matched conditions: ISCHEMIC STROKE
Sponsor: Shanghai East Hospital • Aim: Diagnosis
Last updated Mar 31, 2026 12:11 UTC
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Doctors test eye scan for faster stroke detection
Diagnosis CompletedThis study tested whether a quick, non-invasive ultrasound scan of the eye's optic nerve could help emergency doctors identify which side of the brain is affected in a patient with a suspected stroke. Researchers measured the nerve in 19 adult patients and compared it to the resu…
Matched conditions: ISCHEMIC STROKE
Sponsor: Clinica Mexico • Aim: Diagnosis
Last updated Mar 27, 2026 12:38 UTC
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New scan could spot hidden heart clots causing strokes
Diagnosis CompletedThis study analyzed existing data from 3,940 stroke patients to see how well a special heart scan (cardiac CT) works for finding blood clots in the heart that may have caused the stroke. Researchers compared this scan to the standard heart ultrasound test and tracked patient outc…
Matched conditions: ISCHEMIC STROKE
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Diagnosis
Last updated Mar 20, 2026 14:48 UTC
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Simple tongue brush could save stroke patients from deadly pneumonia
Prevention CompletedThis study tested whether using a special tongue brush could help prevent dangerous lung infections in people who have had a stroke. Researchers enrolled 252 stroke patients to see if brushing the tongue reduced pneumonia and improved swallowing problems. They also checked if it …
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: University Hospital Marburg • Aim: Prevention
Last updated Mar 30, 2026 14:34 UTC
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Robot helps stroke survivors walk again
Symptom relief CompletedThis study tested whether adding a robotic training device to standard physical therapy helps people walk better after a stroke. 62 older adults recovering from a stroke were randomly assigned to receive either standard therapy alone or standard therapy plus sessions with the Lun…
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: University School of Physical Education, Krakow, Poland • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Teaching computers to read your Brain's distress signals
Knowledge-focused CompletedThis study aimed to teach a computer program how to recognize when the brain isn't getting enough blood. Researchers monitored 60 patients during planned surgeries where blood flow to the brain was briefly reduced. They used non-invasive devices to track heart rate, brain oxygen …
Matched conditions: ISCHEMIC STROKE
Sponsor: Linda Block • Aim: Knowledge-focused
Last updated Apr 02, 2026 00:56 UTC
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Researchers map blood thinner levels to improve safety
Knowledge-focused CompletedThis study aimed to establish standard reference ranges for blood levels of three common blood thinners (NOACs) in ethnic Chinese patients with atrial fibrillation. Researchers measured drug levels in 308 patients' blood before and after taking their medication to create these re…
Matched conditions: ISCHEMIC STROKE
Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:44 UTC
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Researchers gather brain injury data to build better monitoring tools
Knowledge-focused CompletedThis study collected detailed brain monitoring data from 162 patients with various brain injuries to build a database for future research. Participants had existing pressure monitors, and researchers used a noninvasive ultrasound device to record blood flow signals. The goal was …
Matched conditions: ISCHEMIC STROKE
Sponsor: Emory University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Scientists use High-Tech scans to peer inside Stroke-Damaged brain cells
Knowledge-focused CompletedThis study used advanced MRI scans to look closely at how water and brain chemicals move inside cells after a stroke. Researchers scanned 24 stroke patients and 24 healthy volunteers to understand the cellular damage and recovery process over three months. The goal was to gather …
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Study probes why strokes strike despite blood thinners
Knowledge-focused CompletedThis study looked at why some people who take newer blood thinners (NOACs) for an irregular heartbeat still have strokes. Researchers reviewed the medical records of 91 Chinese patients to understand the causes, patient characteristics, and treatment outcomes. The goal was to gat…
Matched conditions: ISCHEMIC STROKE
Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Researchers hunt for clues to prevent dangerous bleeding after stroke treatment
Knowledge-focused CompletedThis study looked at 600 stroke patients in the Middle East who received the clot-busting drug alteplase. Researchers wanted to understand what patient characteristics and treatment timing might predict different types of bleeding in the brain after treatment. The goal is to help…
Matched conditions: ISCHEMIC STROKE
Phase: PHASE4 • Sponsor: Kafrelsheikh University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists track Brain's 'Fertilizer' after stroke treatment
Knowledge-focused CompletedThis study aimed to understand if a common stroke treatment (rt-PA) changes levels of a brain protein called BDNF in the blood. Researchers measured BDNF in 50 adults who had a recent ischemic stroke. The goal was to see if BDNF levels could be an early sign of how well a patient…
Matched conditions: ISCHEMIC STROKE
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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Brain scan study seeks clues to prevent future strokes
Knowledge-focused CompletedThis study used detailed 3D brain scans to understand how small blood vessel disease changes over time in people who've had a small stroke. Researchers followed 24 Chinese patients for one year, scanning their brains at the start and end to see how their blood vessels changed. Th…
Matched conditions: ISCHEMIC STROKE
Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:48 UTC