ISCHEMIC STROKE

This study tested a program to help people with heart disease in India get better care. The program used health workers, text messages about healthy living, and a computer tool to help doctors make decisions. 410 adults with heart disease took part to see if the program improved …

This study tested a drug called Renexin CR in 483 people who had a recent stroke not caused by a heart problem. The goal was to see if it could prevent their condition from getting worse or having another stroke within 90 days. Participants were randomly assigned to receive Renex…

This early-phase study tested whether a single intravenous dose of stem cells from donated umbilical cords is safe for people who had an ischemic stroke 3 to 6 months earlier. 18 adults aged 18 to 80 took part. The main goal was to check for side effects, while also looking for s…

This study tested adding dornase alfa, an enzyme that breaks up DNA in blood clots, to standard clot-busting drugs and mechanical clot removal in 330 adults with severe ischemic stroke. The goal was to see if the combination could restore blood flow more quickly before the surgic…

This study looked at whether placing stroke patients in a head-down position after successful emergency treatment could improve their recovery. Researchers enrolled 90 adults who had a major stroke and had their blood flow restored. They measured changes in stroke severity and fu…

This study tested whether a drug called dornase alfa (Pulmozyme) can help open small blood vessels in the brain after a stroke. The trial included 39 people who had a stroke caused by a clot and were already receiving standard clot-busting medicine and a procedure to remove the c…

This study tested a new device called the Supernova stent retriever in 54 people having a severe stroke caused by a large blood clot in the brain. The device is designed to grab and remove the clot, restoring blood flow. The main goals were to see if the device could safely reope…

This study tested whether Enhanced External Counter-Pulsation (EECP) therapy, a treatment that uses inflatable cuffs on the legs to boost blood flow, could help people with severe narrowing of brain arteries. The goal was to see if it improves the brain's ability to adjust blood …

This study tested whether adding Mexidol to standard stroke care helps patients recover better after an ischemic stroke. 304 adults with a first stroke were treated within 48 hours and followed for about 10 weeks. Researchers measured disability, neurological symptoms, and mobili…

This study tested whether giving a clot-busting drug called tenecteplase directly into the brain artery helps stroke patients who still have blockages after a standard clot-removal procedure. 156 adults with acute ischemic stroke were randomly assigned to receive the drug or usua…

This study tested a medical device designed to remove blood clots from the brain in people having a severe stroke. Eight adults who could be treated within 8 hours of symptoms were enrolled. The main goal was to see if the device safely and effectively restored blood flow, with f…

This study tested whether using a special tongue brush (Orabrush) can lower the chance of aspiration pneumonia (a lung infection from food or drink going the wrong way) and improve swallowing in people who had a stroke. About 252 stroke patients took part. Researchers measured pn…

This study looked at nearly 4,000 adults who had a stroke to see if a heart CT scan could find blood clots in the heart that might have caused the stroke. Researchers compared the CT results with standard ultrasound tests. The goal is to improve how doctors detect stroke causes a…

This study tested whether adding a mild electrical current to the brain (called transcranial electrical stimulation) during physical therapy helps people who had a stroke. 60 adults who had a stroke between 2 weeks and 2 years earlier took part. The goal was to see if this combo …

This study looked at how two different feeding methods affect the mental health of stroke patients who have trouble swallowing. 156 adults with ischemic stroke were randomly assigned to receive nutrition through either an intermittent tube or a standard nasogastric tube. Research…

This study tested whether a robotic device called Luna EMG can improve walking, balance, and muscle activity in people recovering from a stroke. 62 older adults (ages 65-86) who had a stroke 4 to 15 weeks earlier took part. Some received standard rehab plus robot-assisted trainin…

This study looked at ways to help stroke survivors with sleep apnea use their CPAP machine regularly during rehab. About 36 people took part. The goal was to see if simple support could improve nightly use and possibly aid recovery.

This study tested a new therapy that uses a brain-computer interface combined with electrical stimulation to help stroke survivors improve their walking. 62 adults who had a stroke at least 6 months earlier and had trouble walking took part. The approach aimed to retrain the brai…

This study tested whether a non-invasive brain stimulation technique called tDCS, combined with balance and walking exercises, could help stroke survivors improve their mobility and thinking. Thirty adults who had a stroke participated. The results suggest tDCS may enhance the be…

This study looked at 50 adults who had an ischemic stroke and received a clot-busting drug called rt-PA. Researchers measured levels of a brain chemical called BDNF in their blood to see if it increased after treatment. They also checked patients' recovery of thinking, movement, …

This study looked at 600 stroke patients in the Middle East to find out what factors predict different types of brain bleeding after receiving the clot-busting drug alteplase. Researchers analyzed patient characteristics, how quickly they got the drug, and stroke risk factors. Th…

This study examined why some people still have ischemic strokes while taking blood thinners called NOACs. Researchers looked at 91 Chinese patients with atrial fibrillation to understand causes and how well they followed their medication plan. The goal was to find preventable fac…

This study looked at 74 people who had a stroke or mini-stroke due to a narrowed brain artery. They all received medication and a procedure to open the artery. Researchers used a special MRI to see if images of the artery wall could help predict if another stroke would happen wit…

This study tested a new ultrasound technique called ultrasound localization microscopy (ULM) to see very small arteries in the brain. 24 people with ischemic stroke or Moya Moya disease took part. The goal was to see if ULM could find more of these tiny arteries than standard met…

This study looked at 308 Chinese adults with atrial fibrillation who had been taking blood thinners (NOACs) for at least 3 months. Researchers measured the amount of medication in their blood before and after taking a dose. The goal was to establish normal reference ranges for th…

This study collected brain signals from 162 patients with brain injuries to create a database for developing noninvasive ways to measure pressure inside the skull. Participants had an existing pressure monitor and also wore a harmless ultrasound device on their head. The goal is …

This study used non-invasive monitors to track heart rate, brain oxygen, and brain waves in 60 patients undergoing carotid surgery or stroke treatment. When surgeons temporarily clamped the carotid artery, the devices recorded the changes. The data will train artificial intellige…

This study used two advanced MRI techniques to look at how water and brain chemicals move inside cells after a stroke. Researchers scanned 24 stroke patients and 24 healthy volunteers to track changes over three months. The goal was to better understand what happens to brain cell…

This study tested whether measuring the optic nerve sheath with ultrasound can predict which side of the brain is affected in people with suspected ischemic stroke. Researchers examined 19 adults in the emergency department and compared ultrasound results with physical exam findi…

This study looked at how small blood vessels in the brain change after a stroke caused by small vessel disease. Researchers used a special 3D X-ray technique to take detailed pictures of these vessels. The goal was to learn more about the disease process, which could help guide f…

This study looked at whether giving a special nutritional drink to people who just had an ischemic stroke is practical and helpful. 24 adults took part, with some getting the drink plus standard care and others just standard care. The main goal was to see if a larger study could …