DIABETES

This pilot study tested a culturally tailored healthy eating and active living program designed to help people with Type 2 diabetes achieve remission. The program involved health coaching and was offered to 30 participants in low-income Memphis neighborhoods, while another 30 rec…

This small, completed study tested if a clinical trial could be run remotely to find the best personalized drug plan for protecting the kidneys of people with type 2 diabetes. Twelve participants tried a drug called empagliflozin at home, and based on their kidney test results, s…

This study tested a special program to help South Asian adults with uncontrolled diabetes better manage their condition. The program used community health workers to coach patients, connect them to local resources, and coordinate with their doctors. The main goal was to see if th…

This study tested a program to help people who recently lost weight keep it off long-term. It trained regular clinic staff, like nurses and medical assistants, to provide coaching through an online patient portal. The goal was to see if this approach, integrated into normal healt…

This pilot study tested a program called SMART-HABITS-4-Health to see if it could help people with chronic kidney disease, diabetes, and high blood pressure manage their condition better. 70 participants used a smartphone app to track their blood pressure and received daily text …

This study tested whether treating gum disease helps improve blood sugar control in people with diabetes. Researchers divided 91 diabetic patients with gum disease into two groups: one received immediate gum treatment, while the other received delayed treatment after the study. T…

This small, early-stage study tested whether a hormone called apelin can improve how the body uses insulin in people with type 2 diabetes. Nine volunteers with well-controlled diabetes received a continuous infusion of apelin or a placebo. The main goal was to see if apelin made …

This study tested whether pairing people with a community health worker for 10 months could help them better manage chronic health conditions like diabetes, high blood pressure, and obesity. The program provided navigation help to access health services, education, and support fo…

This study tested whether two simple exercise programs could help people with type 2 diabetes. Researchers compared a specific foot-ankle exercise routine, a walking program, and standard education to see which best improved foot nerve health, stress, and quality of life over 12 …

This study tested whether replacing sitting time with standing and light walking could improve daily blood sugar control. It involved 18 South Asian adults with overweight or obesity who normally sat a lot. Participants tried two different 4-day routines: one with lots of sitting…

This study tested whether specially trained community health workers could help young adults from underrepresented minority groups start and keep using diabetes technology like continuous glucose monitors and insulin pumps. For 9 months, 119 participants were randomly assigned to…

This study tested a new endoscopic procedure that aims to regenerate the lining of the small intestine to help control type 2 diabetes. Researchers enrolled 20 adults whose diabetes wasn't well-controlled on 2-3 non-insulin medications. The main goal was to check if the procedure…

This small pilot study tested two different computer algorithms designed to automatically adjust insulin delivery for people with type 1 diabetes. Five adults who already used insulin pumps wore experimental closed-loop systems that continuously monitored blood sugar and calculat…

This study tested whether a smartphone app using artificial intelligence (AI) could help adults with type 2 diabetes manage their condition better than standard care. The AI system, called X-Life, gave personalized advice on diet and activity based on data from a continuous gluco…

This trial tested whether a new minor procedure called the 'inforatio technique' could help diabetic foot ulcers heal faster. One hundred patients with these hard-to-heal sores were randomly assigned to receive either standard wound care alone or standard care plus this new techn…

This study tested a new system to help doctors refer more patients with diabetes to a proven education program. The program teaches people how to manage their diabetes to control blood sugar and avoid complications. Researchers worked with 22 clinics in Kentucky, using technology…

This study tested whether adding the antibiotic rifampin to standard treatments could help prevent foot and leg amputations in diabetic patients with serious bone infections. Researchers followed 843 veterans with diabetes and foot bone infections, giving half rifampin and half a…

This large, completed study tested two different drug combinations to see if they could help people with chronic heart failure live longer and stay out of the hospital. It involved about 1,100 participants with weakened hearts. One part tested a blood pressure drug combo (Hydrala…

This study tested whether quickly improving blood sugar control for 2-3 days before major abdominal surgery helps patients recover better. It involved 53 adults with uncontrolled diabetes. Researchers compared patients who received this short-term control to those who followed st…

This study tested a flexible lifestyle program for people with conditions like insulin resistance, obesity, or prediabetes. It started with either nutrition or exercise counseling. If a person's insulin resistance didn't improve enough after 8 weeks, the program could switch them…

This small study tested a program to help people on weight-loss medications (like Ozempic or Wegovy) become more physically active. Fifteen patients received a Fitbit and worked with a health coach for 12 weeks. The main goal was to see if this combined approach was practical and…

This study tested whether quercetin, a natural substance found in foods like apples and onions, could help control blood sugar. Researchers gave 24 adults with obesity or type 2 diabetes either quercetin or a placebo during sugar tolerance tests to see if it slowed sugar absorpti…

This study tested whether an oral medication (glyburide) works as well as insulin injections for managing diabetes that develops during pregnancy. Researchers enrolled 914 pregnant women whose blood sugar wasn't controlled by diet alone. The trial compared whether the pill was as…

This study tested whether a series of online cooking and nutrition classes could help people with type 2 diabetes and a high body mass index (BMI) improve their health. 89 participants from specific clinics learned about healthy eating and cooking skills through virtual classes. …

This early-stage study tested the safety and effects of a new injectable drug called CT-388. It involved 129 overweight or obese adults, some with type 2 diabetes. Researchers measured how the body processes the drug and its impact on weight and blood sugar levels.

This study tested a new way to help people with HIV in rural Kenya stay in care and keep their virus under control. Researchers combined local HIV and chronic disease check-ups with existing community savings groups. They wanted to see if making care easier to access and improvin…

This study aimed to see if a type of diabetes medication (SGLT2 inhibitors) could help protect kidney function in people with chronic kidney disease, whether they had diabetes or not. Researchers compared changes in a key measure of kidney health (eGFR) in 60 adult participants w…

This 12-month study tested a new automated system that delivers both insulin and glucagon to manage type 1 diabetes. It involved 243 adults in the Netherlands and compared this dual-hormone system to their current standard or advanced care. The main goal was to see if the new sys…

This study tested a new automated tool designed to screen for diabetic retinopathy, a serious eye complication of diabetes. The goal was to see if this tool could work well in primary care clinics, making screening easier and more accessible for people with diabetes. Researchers …

This study tested a new device called the Cmate glucose analyzer, which aims to measure blood sugar levels without needing a finger prick. Researchers compared its readings against traditional blood tests from 40 adults, including healthy people, those with prediabetes, and those…

This study tested how accurately a new blood glucose monitor (the LS-9) measures sugar levels in the blood. It involved 219 adult volunteers with varying blood sugar levels. The main goal was to see if the device's readings were reliable and met international quality standards fo…

This study tested how well a new, under-skin glucose monitor works when people take acetaminophen (like Tylenol). 31 adults with diabetes wore the new monitor and a standard one for three days. On the final day, they took acetaminophen so researchers could check if the painkiller…

This study tested a new wearable glucose monitor that sticks to the skin like a patch. 247 adults with diabetes wore the device for up to a week to see how accurately it measured blood sugar compared to standard fingerstick tests and lab equipment. The goal was to gather data to …

This study tested whether adding a food incentive program to standard diabetes prevention classes helps people stick with the program and make lasting healthy changes. It involved 61 adults at risk for developing diabetes. The goal was to see if providing support for healthy eati…

This study tested whether helping pregnant women sign up for a government food program (WIC) online, and offering talks with a dietitian, would get more people to use these services. Researchers worked with 240 pregnant women receiving care at Geisinger clinics, dividing them int…

This study tested a personalized diet and exercise program designed for Hispanic women who were overweight or obese at the start of their pregnancy. The goal was to help them gain a healthy amount of weight during pregnancy, lose weight after giving birth, and improve their body'…

This study tested a two-part program designed to lower the risk of developing chronic diseases like diabetes and high blood pressure in unemployed adults. It worked by adding a health prevention program to existing job training services and by training workplace supervisors to be…

This study looked at whether a specific diabetes medication (semaglutide) might help prevent dementia compared to other common diabetes drugs. Researchers analyzed health records from over 740,000 Americans aged 65+ with type 2 diabetes who had no prior dementia. The goal was to …

This study tested a new home-visit program designed to help new mothers improve their heart health. The program, called Family Check-Up Heart, provided 117 low-income mothers with coaching on diet, exercise, and stress management. Researchers compared it to a standard home-visit …

This study tested whether a 3-month mobile health (mHealth) support program could help family caregivers. The program aimed to reduce the stress and burden felt by people caring for a loved one with both Alzheimer's dementia and type 2 diabetes. Researchers measured changes in ca…

This small pilot study tested whether a specific foot and ankle exercise program or a walking program could help people with diabetes. Researchers wanted to see if these exercises were practical to do and if they might improve nerve pain, stress, and quality of life. The study in…

This study tested whether a diabetes medication called acarbose, when carefully adjusted using a continuous glucose monitor, could reduce pain in people with diabetic nerve damage. The trial involved 170 adults with type 2 diabetes who experienced painful neuropathy and unstable …

This study tested a home exercise program for cancer survivors who also have diabetes or high blood pressure. Participants used a wearable device and phone app to track their activity and get feedback while choosing from different exercise options like walking or yoga. The main g…

This study aimed to understand how Mexican American families talk about their risk for common diseases like diabetes, heart disease, and cancer. Researchers worked with 498 adults from multigenerational households to see if sharing personalized risk information with the whole fam…

This study aimed to understand if specific bacteria found in the fatty plaques of neck arteries are linked to a higher risk of stroke or other complications after surgery. Researchers observed 200 patients in China who were having surgery to clear a blocked carotid artery. They a…

This study aimed to understand exactly how lifestyle changes like diet and exercise help control blood sugar in people with diabetes. Researchers closely monitored 61 adults with diabetes to see how their bodies responded at a deep molecular level. The goal was to gather detailed…

This study aimed to measure how often older adults with diabetes living in long-term care facilities experience dangerously low blood sugar. Researchers used a continuous glucose monitor worn for 10 days on 86 residents to track these events. The goal was to gather better informa…

This study tested whether a continuous glucose monitor (Freestyle Libre) could help manage blood sugar in diabetic patients starting chemotherapy. Researchers wanted to see if this device could detect dangerous highs and lows in blood sugar that might affect chemotherapy safety a…

This study aimed to understand if nerve blocks used for hand or wrist surgery last a different amount of time in people with kidney failure or diabetes compared to healthy people. Researchers enrolled 120 patients having surgery to measure how long the numbing effect lasted. The …

This research project followed 2500 Black adults in five countries to understand if the amount of energy people burn through daily activity is linked to weight gain and diabetes risk. Participants wore activity monitors, and some had special water tests, to accurately measure the…

This study aimed to see if measuring how the body handles fats (triglycerides) could help identify which patients with stable heart disease are at higher risk for future heart problems. Researchers followed 514 people with coronary artery disease for 18 months, tracking their tri…

This research study aimed to understand if viruses in pregnant women, especially those with diabetes, might increase the risk of heart defects in their babies. Researchers analyzed blood and stool samples from 114 women to look for viruses and the body's immune response to them. …

This study aimed to understand why keeping weight off is so hard. After losing weight, 234 adults followed one of three diets with different amounts of carbs and fat, but the same protein. Researchers carefully measured how many calories their bodies burned and other health marke…

This study aimed to find out how often elderly people with diabetes living in nursing homes experience low blood sugar (hypoglycemia), which can be dangerous but often goes unnoticed. Researchers monitored 29 residents over 60 years old to measure these events. The goal was to be…

This study tested whether teaching mothers about their family's health history could motivate their families to adopt healthier behaviors. Researchers gave 310 mothers a toolkit showing their risk for diseases like diabetes, cancer, and heart disease based on family history. They…

This study aimed to understand how women's bodies absorb and use vitamin E, an important antioxidant. Researchers enrolled 50 women, including some who were obese or had diabetes, to measure how different amounts of dietary fat and vitamin C affect vitamin E levels in the blood a…

This study aimed to understand why common screening tests for diabetes and heart disease often fail women of African descent. Researchers compared risk factors like blood sugar, body fat, and triglycerides in 146 healthy African, African-American, and white women who were federal…

This study aimed to learn how family members share health information when someone has a genetic-related disease like sickle cell, diabetes, or cancer. Over 1,000 adults who either had such a disease or were related to someone who did completed surveys about their family's health…

This study tested a new AI system designed to give personalized lifestyle advice to people with type 2 diabetes or prediabetes. Twenty participants used the system, which analyzed their glucose, activity, and sleep data to suggest diet and exercise changes. The main goal was to s…

This study aimed to understand the role of a brain chemical called 26RFa, which is linked to hunger, in obesity and type 2 diabetes. Researchers measured levels of this hormone in 62 obese women (some with diabetes, some without) before and after weight-loss surgery, and compared…