DIABETES

This study is testing if adding the diabetes drug empagliflozin helps people who have received a transplant of their own insulin-producing cells. It will involve 40 adults who still have some cell function after their transplant. Researchers will compare different doses of the dr…

This study aims to see if a common type of diabetes drug (GLP-1 RA) can improve the buildup of harmful fats in the liver of people who have fatty liver disease, diabetes, and obesity. Researchers will compare liver and blood samples from 30 people who have been on the drug for a …

This study is testing if it's safe and practical for pregnant people with type 1 or type 2 diabetes to continue using their personal insulin pump during labor. Currently, they are often asked to switch to insulin given through an IV, which can be stressful and may disrupt blood s…

This study will test whether a large language model (like a sophisticated AI chatbot) can help community doctors better coordinate care for adults with high blood pressure plus either diabetes or high cholesterol. It will compare the AI-assisted management approach to standard ca…

This study tests whether community health workers can help people better manage multiple chronic conditions like diabetes, high blood pressure, and heart disease. 300 adults with at least two chronic health conditions will work with trained health coaches for 9 months to develop …

This study aims to see how well the Omnipod 5 automated insulin pump system works for people with Type 1 diabetes in their daily lives. It will follow about 150 patients, including children and adults, for one year to measure blood sugar control, quality of life, and safety. The …

This study tests whether a virtual meeting with a nurse before a doctor's visit can help people with diabetes and early kidney disease. The nurse provides education, motivation, and connects people to support services. Researchers want to see if this approach helps patients bette…

This study is testing a 6-week support program for older adults who have both diabetes and mild memory problems. The program involves their primary caregivers and aims to improve how patients manage their diabetes day-to-day and support their cognitive health. Researchers will me…

This study is testing a portable, automated pill dispenser called Mobili® to see if it helps people with diabetes or heart disease take their multiple medications correctly. The device alerts patients when it's time for a dose and can alert a pharmacist if a dose is missed. Resea…

This study aims to help people with diabetes in rural Kentucky by connecting clinics with community resources. It will test whether providing patient navigators and support for needs like food and housing improves diabetes control and quality of life. The program will involve 12,…

This study aims to find out if aiming for a tighter, more normal blood sugar range is better than the current standard for children and teens with Type 1 diabetes. It will involve 120 young people who use automated insulin pumps. Researchers will compare the two targets over a ye…

This study offers a medical device treatment to people with type 2 diabetes who were in the placebo group of a previous trial. It aims to collect real-world safety and performance data on the Endogenex System, which is designed to help control blood sugar. The study will enroll a…

This study is testing whether providing different amounts of monthly grocery money helps low-income people with diabetes or high blood pressure better manage their health. About 4,450 participants will be randomly assigned to receive either an $80 or $120 monthly food card for on…

This study tests whether continuous glucose monitors (CGMs) help low-income, uninsured, or Medicaid patients with type 2 diabetes better manage their blood sugar. Fifty participants will be randomly assigned to either use a CGM for six months or continue with traditional finger-p…

This study is testing if wearing a continuous glucose monitor (CGM) helps people with severe obesity manage their blood sugar better before and after weight-loss surgery, compared to the standard finger-prick method. Researchers will recruit 20 people in Louisiana who are schedul…

This study is testing if a wearable sensor that continuously checks blood sugar can help manage diabetes in hospitalized patients who need insulin through an IV. It aims to see if this method is as effective as standard care while being more convenient for nurses and less disrupt…

This study is testing if a group-based care model can help people in Nepal better manage high blood pressure and diabetes. About 1,110 adults with these conditions will be assigned to either continue their usual care or join a new program with monthly group sessions for education…

This study tests whether having a real-time online team of heart specialists make treatment decisions during a patient's heart scan leads to better outcomes than standard care. It involves 1,350 adults with both diabetes and severe blockages in all three main heart arteries. The …

This study is testing a new support program called PINPOINT to help women with diabetes or obesity get screened for cervical cancer. It will work with 20 women who are overdue for screening to see if the program is practical and well-liked. Participants will either receive the ne…

This study is testing whether a small device that gently stimulates nerves near the ear can help reduce nausea, vomiting, and other stomach symptoms in people with diabetes. Researchers want to see if this stimulation affects the 'vagus nerve,' which controls stomach function. Ab…

This study aims to understand how diabetes and obesity develop and change over time, especially in younger people. Researchers will collect health information and samples (like blood and saliva) from up to 1,000 participants during their regular doctor visits. The goal is to gath…

This study aims to improve a system that helps doctors identify physically inactive patients and refer them to local exercise programs. It will test new support methods for clinics to see if they can get more eligible patients connected to these community resources. The goal is t…

This study aims to understand why some stroke patients get worse after a successful procedure to remove a blood clot. Researchers will use a non-invasive brain ultrasound on 100 patients to measure blood flow after the procedure. The goal is to find patterns that could help docto…

This study will create a long-term health registry tracking 10,000 adults with diabetes and related metabolic conditions like high blood pressure and liver disease. Researchers will collect routine medical information over at least 10 years to identify patterns that could improve…

This study is testing how easy it is to use a new wrist-worn device called the Argus CGM. The device uses light sensors and artificial intelligence to estimate blood sugar levels without needing to prick the skin. About 100 adults with type 1 diabetes, type 2 diabetes, or prediab…

This study is collecting blood samples from 30,000 adults in the UK with various health conditions to help develop and improve rapid diagnostic tests. Participants will provide blood samples that researchers will use to create better testing methods for conditions like blood clot…

This study aims to understand how different people respond to the diabetes medication sitagliptin. Researchers are recruiting 400 healthy, non-diabetic volunteers from the Old Order Amish community in Pennsylvania. Participants will take part in two clinic visits over 7 weeks whe…

This registry aims to collect long-term safety and health outcome information from people with type 2 diabetes who have already been treated with the Endogenex System. It will follow up to 500 participants for five years to monitor their health after the procedure. The goal is to…

This study follows 450 people with diabetes over time to understand if low levels of a nutrient called glutamine in their blood are linked to a higher risk of future heart problems like heart attacks or strokes. It is an observational study, meaning researchers will collect blood…

This study aims to understand how eating meals with different nutrients—like high-fat or high-carbohydrate breakfasts—affects fat levels in the blood. Researchers will compare 100 participants, including healthy volunteers and people with conditions like kidney disease or metabol…