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Could zapping nerves save limbs? new study tests electrical stimulation for diabetic neuropathy

NCT ID NCT07696988

Not yet recruiting Knowledge-focused Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study investigates whether targeted electrical stimulation of peripheral nerves can improve blood flow and blood vessel function in the lower limbs of veterans with diabetic peripheral neuropathy. Researchers will measure skin blood flow, vessel density, and oxygen levels using laser and photoacoustic imaging. The goal is to develop a sensitive test for nerve-vessel health and explore whether stimulation can enhance circulation, potentially reducing the risk of limb complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Chronically Implanted Neural and Muscular Interface
What this could lead to
If successful, this could point toward a new way to improve blood flow and prevent limb complications in people with diabetic nerve damage.
What could go wrong
This is a small, early-stage study focused on measuring physiological responses, not treating disease. The device is experimental and may not improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus diabetic neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES LOWER LIMB AMPUTEES

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Louis Stokes VA Medical Center, Cleveland, OH

    Cleveland, Ohio, 44106-1702, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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