Blood sugar rollercoaster in frail seniors: which insulin works best?

NCT ID NCT02486341

Completed Knowledge-focused Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how much blood sugar levels go up and down during the day in frail or disabled patients over 75 with diabetes who use basal insulin. Researchers used a continuous glucose monitor for 5 days to compare two types of insulin: human NPH and long-acting analogues. The goal was to see if one type leads to more stable blood sugar levels, which could help guide better treatment for this vulnerable group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Insulin (NPH or long-acting analogues)
What this could lead to: If successful, this could help doctors choose the best basal insulin for frail elderly patients to reduce dangerous blood sugar swings.
What could go wrong: This is a small, observational study with only 30 participants, so results may not apply to all older patients. It does not test a new treatment.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES

Contacts and locations

Locations

University Hospital of Bordeaux - Xavier Arnozan Hospital

Pessac, 33600, France

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