Study reveals which diet keeps you burning calories after shedding pounds

NCT ID NCT02068885

First seen Jan 11, 2026 · Last updated Jun 23, 2026 · Updated 30 times

Summary

This study looked at how different diet compositions affect the number of calories people burn and their risk for chronic diseases like diabetes and heart disease after losing weight. Over 200 adults with overweight or obesity followed a weight-loss phase, then a weight-maintenance phase, and finally an unrestricted eating phase. Researchers measured total and resting energy expenditure using special tracer methods and respiratory gas exchange.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Framingham State University

    Framingham, Massachusetts, 01702, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help identify which diet composition best supports weight-loss maintenance and reduces risks for obesity-related diseases like diabetes and heart disease.

What could go wrong

This is an observational feeding study, not a treatment trial. Results may not apply to everyone, and dietary effects can vary widely among individuals.

Conditions

The condition(s) this trial relates to.

cardiovascular disorder diabetes mellitus Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.