Study reveals which diet keeps you burning calories after shedding pounds

NCT ID NCT02068885

Completed Knowledge-focused Sponsor: Boston Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how different diet compositions affect the number of calories people burn and their risk for chronic diseases like diabetes and heart disease after losing weight. Over 200 adults with overweight or obesity followed a weight-loss phase, then a weight-maintenance phase, and finally an unrestricted eating phase. Researchers measured total and resting energy expenditure using special tracer methods and respiratory gas exchange.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help identify which diet composition best supports weight-loss maintenance and reduces risks for obesity-related diseases like diabetes and heart disease.
What could go wrong: This is an observational feeding study, not a treatment trial. Results may not apply to everyone, and dietary effects can vary widely among individuals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder diabetes mellitus Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASE DIABETES OBESITY

Contacts and locations

Locations

Framingham State University

Framingham, Massachusetts, 01702, United States

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