AUTISM SPECTRUM DISORDER

This study tests whether a wide-spectrum nutritional supplement can improve mitochondrial function in children with autism spectrum disorder (ASD). Mitochondria are the energy factories in cells, and some children with ASD have abnormal mitochondrial activity. The trial enrolls c…

This study tested a computer program called Work Chat that helps young adults with autism practice conversations with coworkers, customers, and supervisors in a virtual workplace. 44 participants used the tool to improve social skills needed for jobs. The goal is to help more peo…

This study tested whether a 16-week lifestyle program delivered through WeChat could help children with autism (ages 8-12) manage their weight. 276 families were split into three groups: usual care, the WeChat program alone, or the program plus weekly group coaching. The main goa…

This study compared two FDA-approved medications, risperidone and aripiprazole, used to treat irritability in children with autism. The goal was to see which one causes more weight gain. Thirty children under 18 who had never taken these drugs before were followed during routine …

This study tested whether a child's own bone marrow stem cells, combined with educational therapy, can safely reduce autism symptoms. 54 children aged 3-7 with moderate to severe autism took part. Researchers measured changes in behavior, social skills, and quality of life. The g…

This study tested a program called Autism Eats, designed to help children with autism spectrum disorder (ASD) eat more fruits and vegetables and try new foods. The program was offered through early intervention services for children up to 36 months old. Researchers compared the p…

This study tested a combination therapy—including antibiotics, a bowel cleanse, stomach acid suppressants, and beneficial bacteria from human feces—to treat gastrointestinal problems in 18 children with autism. The goal was to see if the treatment could reduce gut symptoms like p…

This completed study tested whether a special diet plus a nutritional supplement called T-2 could improve thinking skills, sleep, and overall health in 76 people with Down syndrome, autism, or ADHD, aged 2 to 35. Participants followed either the diet alone, the diet plus suppleme…

This study tested whether a blood test called exome sequencing can find genetic causes of autism better than standard care. Researchers studied 300 people with autism to see if the test could identify risk genes. The goal is to improve diagnosis and help families understand the b…

This study tested whether an iPad game (Play.Care) could help diagnose autism spectrum disorder (ASD) in children aged 2.5 to 5 years. The game measures how children move while playing, since movement differences may be early signs of autism. Researchers compared the game's resul…

This study tested a device called EarliPoint that tracks where children look while watching short videos. The goal was to see if it could help diagnose autism spectrum disorder (ASD) in children ages 2.5 to 7. Nearly 1,000 children participated, and the device's results were comp…

This study tested a training program called SAFE for people with intellectual or developmental disabilities who are working or looking for work. The program taught them about COVID-19, how to use protective gear, social distancing, and self-advocacy. 67 young adults took part, an…

This pilot study in Pakistan tests a culturally adapted psychological therapy (Y-CMAP) for autistic young people aged 14-24 who have a history of self-harm. The therapy is based on cognitive behavioral therapy and includes 8-10 sessions over three months. The study will check if …

This study tested whether a single infusion of stem cells from donated umbilical cord tissue could improve social communication in children with autism. 137 children aged 4 to 12 took part. The main goal was to see if their socialization and communication scores improved after si…

This study tested whether an intensive, center-based version of Pivotal Response Treatment (PRT) can improve social communication in preschoolers with autism. 75 children aged 2 to 4 years participated. The therapy combined weekly parent training with center-based sessions for a …

This study tested two ways to improve dental care for children with autism. One group received a dental toolkit with tips and resources. The other group got the toolkit plus special parent training to help with brushing and dentist visits. The goal was to see if the extra trainin…

This study tested a structured online program for parents of children with autism or ADHD. 90 families took part to see if the program could lower parental stress, improve coping skills, and boost social support. Researchers compared parents who received the program to those who …

This study tests a 10-week visual rehabilitation program for children with autism spectrum disorder who also have vision problems. The program uses games and activities to improve how children use their eyes and process visual information. Researchers want to see if better vision…

This study tested a new behavior therapy for teens with autism who struggle with irritability and aggression. The therapy teaches emotion regulation and coping skills for the challenges of growing up. 65 adolescents participated, and researchers measured changes in aggressive beh…

This study tested a program called ASPEN, which coaches parents of young children with autism in low-resource communities. The program includes 12 sessions teaching parents strategies to improve their child's social communication and play skills, while also reducing parenting str…

This study tests whether pediatric massage can improve behavior and social skills in children aged 3 to 10 with autism spectrum disorder (ASD). Children receive massage twice a week for 12 weeks from a professional, plus at-home massage from trained parents. Researchers also use …

This study tested whether a natural supplement called ultramicronized palmitoylethanolamide (umPEA) can improve smell, taste, and other sensory issues in children with autism. Eighty children took either umPEA or a standard treatment (probiotics plus omega-3) for six months. Rese…

This study tested a program called the Westmead Feelings Program 2 for Chinese children with autism in Hong Kong primary schools. The goal was to help them better understand and manage emotions. 85 children took part, and researchers measured changes in emotional skills and behav…

This study tested whether a nasal spray containing vasopressin, a natural hormone, can improve social functioning in children with autism. 157 children aged 6 to 17 took part. Researchers measured changes in social responsiveness and overall symptoms over 8 weeks.

This study tested whether playing virtual reality games (like Nintendo Switch Sports) could improve balance and walking in young people with autism, compared to standard physical therapy exercises. Thirteen participants aged 7-22 did six sessions over two weeks at home via Zoom. …

This study tested a psycho-educational program designed to help family caregivers of children with autism become more aware of their own needs and better at seeking support. Fifty caregivers of children aged 6 to 12 took part. The program involved teaching coping strategies and w…

This study tested whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can improve core symptoms in 200 children with autism spectrum disorder. Children received either real or sham stimulation over five days, with multiple…

This study tested an experimental drug called ML-004 in 168 adolescents and adults with autism spectrum disorder to see if it could improve social communication skills. Participants were randomly assigned to receive either the drug or a placebo for several weeks. The main goal wa…

This study tested a home-based brain-training program in 12 autistic adults who also had insomnia. Participants played cognitive games for 18 hours over 6 weeks while wearing a sleep tracker and filling out sleep diaries. The goal was to see if the training was usable and could i…

This study tested a probiotic (BB-12 with LGG) in 123 children with autism and stomach problems. The goal was to see if different doses are safe and can improve behavior and gut health. Researchers tracked side effects, behavior changes, and gut bacteria over 56 days of treatment…

This study adapted a behavioral activation treatment called BeatIt-MV to help improve mood in minimally verbal autistic adults with depression. Nine adults took part, along with a caregiver. The therapy focused on increasing meaningful activities like recreation and social time. …

This study tested a 12-session outdoor group training program where children interacted with animals to build resilience. It included 107 children aged 2-4 or 8-12 who had either autism or a history of stressful life events. The goal was to see if this approach could help them be…

This study tested a Spanish-language program called Unstuck and On Target with 20 families in Ecuador. Children aged 8-11 with autism or ADHD took part in an 8-week program to improve flexibility and problem-solving. The goal was to see if the program was practical and helpful fo…

This study tested a non-invasive brain stimulation technique called TMS in 20 young adults with autism. The goal was to see if stimulating a specific brain area could improve how they look at faces and interact socially. Participants received 10 daily sessions, and researchers me…

This study tested whether bumetanide, a diuretic, can improve social skills in children with autism. Researchers used a blood test and machine learning to pick children likely to respond. 66 children aged 3-6 took bumetanide or standard behavioral therapy for three months. The go…

This pilot study tested whether electromagnetic therapy (EMT) can help improve autism symptoms in children. Thirty children aged 3-12 with mild to moderate autism were randomly assigned to receive either their usual care plus EMT or usual care alone. The treatment involved 30 ses…

This study tested a special light helmet (called tPBM) on 6 autistic children aged 4–12 who also had abnormal brain activity or epilepsy. The helmet delivered near-infrared light to specific brain areas twice a week for 10 weeks. The goal was to see if it could safely improve foc…

This study looked at whether teaching parents to use Reciprocal Imitation Training (RIT) at home helps young children with autism improve their imitation and social skills more than therapist-only sessions. Eighteen children aged 2 to 5 years participated. The goal was to see if …

This study tested whether wrapping children with autism in sheets (wet or dry) can reduce severe injurious behaviors like self-harm or aggression. 48 children took part, and researchers compared wet wraps to dry wraps. The goal was to see if this gentle, drug-free approach could …

This study tested whether a mix of vitamins and supplements could ease autism symptoms in 88 children aged 2.5 to 6 years. Half received the supplements plus behavioral therapy, the other half only behavioral therapy. After three months, researchers measured changes in social ski…

This completed study tested whether Vita 6 (a vitamin supplement) or zinc, each given alongside behavioral therapy, could reduce autism severity in children aged 3-12. Sixty-four newly diagnosed children who were not on any other treatment took part. The goal was to see if either…

This small pilot study tested a structured plate with separate compartments to help children aged 5 to 7 with autism and feeding difficulties eat more easily. Six children used the plate during school lunch three times a week for two months, guided by an occupational therapist. R…

This study tested a therapy called Sentido's Model in 24 children aged 3 to 7 with autism or other neurodevelopmental challenges. The therapy combines behavior analysis, sensory integration, and stress science to help children improve adaptive behaviors like communication and dai…

This study tested a custom probiotic blend in 296 children and adults with autism spectrum disorder. The goal was to see if the supplement could improve autism symptoms and gastrointestinal issues. Participants took a personalized mix of probiotics, prebiotics, and botanicals, an…

This study tested whether a virtual reality (VR) product called Floreo can help autistic children improve their social skills. 117 children aged 5 to 18 used the VR program twice a week for 12 weeks. Researchers compared the Floreo VR group to a control VR group to see if there w…

This pilot study tested whether a 12-week course of a synbiotic supplement (probiotics plus prebiotics) could help reduce anxiety in 30 children with autism spectrum disorder. The main goals were to see if the treatment was safe and tolerable, and to measure any changes in anxiet…

This study looked at whether adding Ayres Sensory Integration therapy to usual education helps preschool children with autism. 63 children aged 4 to 5 years took part. The therapy focused on improving daily skills and sensory processing over 12 weeks.

This study tested a 6-week mobile app designed to support Chinese parents of children with autism. The app provided knowledge, skills, and mindfulness training. 852 parents took part to see if the app could reduce anxiety, depression, and stress while boosting parenting confidenc…

This pilot study tested a wearable device that gently stimulates a nerve in the ear to help manage anxiety in teenagers with autism. Ten participants used the device at home twice daily for four weeks. The goal was to see if it was safe and easy to use, not yet to prove it works.…

This completed trial tested whether LEGO therapy can improve social skills in 50 adolescents aged 10–14 with high-functioning autism. Participants attended 12 weekly 90-minute group LEGO sessions over 3 months. Researchers compared their social skills to a control group who conti…

This study tested whether pregnenolone, a natural hormone in the brain, can help reduce irritability and improve social communication in people with autism. 40 participants aged 14 to 25 took either pregnenolone or a placebo for several weeks. Researchers measured changes in beha…

This study tested an in-person mindfulness program for adolescents with autism and their caregivers. The goal was to help reduce stress, anxiety, and depression. 28 teens and their caregivers took part in group sessions. The program aimed to improve mental health and well-being.

This study tested a school-based program where teachers were trained to use special techniques to help preschoolers with autism improve their social and communication skills. 700 children aged 3 to 6 took part. The goal was to see if this approach works in real classrooms and can…

This study tested whether a gentle, non-invasive brain stimulation technique could safely improve social symptoms in children with autism. 36 children aged 4-10 received either real stimulation or routine rehabilitation for 5 days. The goal was to see if the treatment is safe and…

This study tested whether taking part in art activities like theatre, dance, visual arts, music, or cinema can improve mental health. 541 adults with psychiatric diagnoses were randomly assigned to either an art program or a waitlist. Researchers measured changes in depression an…

This study looked at whether a 16-week swimming and water exercise program could improve behavior and physical skills in 35 boys aged 6 to 12 with mild autism. Half the boys did the water exercises twice a week, while the other half continued their usual school routine. The resul…

This study tested a structured movement program (Sherborne Developmental Movement) in 30 children aged 8-12 with autism. The program aimed to improve how they process sensory information, move their bodies, and perform everyday tasks. Results were measured using motor skill tests…

This study tested whether having a therapy dog present during dental visits could reduce anxiety and improve cooperation in autistic children aged 6 to 17. Fifty children received two sessions with a dog and one without. The goal was to see if the dog's presence made later visits…

This study tested a structured program to help children and teens with autism, developmental delays, or intellectual disabilities cooperate during eye exams. Twenty participants attended six training sessions that used practice in a mock clinic, rewards like snacks or toys, and o…

This study tested a new anxiety program designed for autistic youth ages 7 to 17. The program was delivered in community care centers to make it more accessible. Researchers wanted to see if it was practical and helpful for reducing anxiety symptoms. The study involved 32 partici…

This study tested a video-based therapy called Focused Acceptance and Commitment Therapy (FACT) for parents of children with special health needs, like ADHD or autism. The goal was to see if it could reduce stress, anxiety, and depression. 104 parents took part, and the therapy w…

This study tested whether adapted judo training plus nutritional counseling could improve physical fitness, body composition, and stability in children and adolescents with autism spectrum disorder (ASD). One hundred participants aged 7–14, with and without ASD, took part in 10 m…

This study looked at whether circuit aerobic training (like walking and stepping) or circuit resistance training (like hand grip exercises) can improve heart and lung fitness in children with autism aged 7 to 17. Thirty-two children took part, and researchers measured their breat…

This study tested a 40-week music program using bone conduction headphones in 8 children with autism who are overly sensitive to sound. The goal was to see if the program could reduce their discomfort with noise and improve their daily living skills. Researchers measured changes …

This study tested whether gabapentin, a medication that boosts a calming brain chemical called GABA, could improve social thinking in teens with autism. Sixteen adolescents aged 13-17 took gabapentin for 8 weeks while researchers measured brain GABA levels and social abilities. T…

This study tested a school-based program called Unstuck & On Target: High School for autistic teens. The program teaches skills like flexibility, planning, and self-advocacy through 25 lessons led by school staff. Researchers measured changes in classroom behavior and daily livin…

This study looked at whether a 12-week structured movement program could help young children (ages 4-6) with autism improve their motor skills and daily functioning. Twenty-eight children participated; some did the movement program twice a week plus their usual education, while o…

This phase 3 trial tested an experimental drug called AST-001 in 169 children with autism spectrum disorder. The goal was to see if it improves core symptoms like social communication and repetitive behaviors better than a placebo. The study is already completed, and results will…

This study tested a device called transcranial photobiomodulation (tPBM), which shines invisible light on the front of the brain through a headband. Researchers wanted to see if it is safe and can improve social and behavioral symptoms in adults with autism. Forty-one adults took…

This study tested whether adding fully immersive virtual reality (VR) training to standard psychological and behavioral therapy helps children with autism. 120 children aged 2 to 12 took part; 62 received VR plus therapy, and 58 received therapy alone. The goal was to see if VR c…

This study tested a theatre-based program called SENSE Theatre for adults with autism. 72 participants took part in 10 sessions of role-play and peer interaction, ending with a public performance. The goal was to see if this approach could improve social skills like reading faces…

This study tested a 12-week motor support program in 28 children aged 4-6 with autism. The program added 40-minute sessions twice a week to regular special education. Researchers measured changes in gross motor skills, sensory processing, and autism symptoms using standard tests.…

This study tested a flexible, play-based program to improve social communication and language in toddlers (ages 2-3) with autism. 199 children took part in community early-intervention settings. The program adjusted the type and amount of one-on-one play coaching based on each ch…

This study tested whether a daily routine of gentle massage and deep breathing, called qigong sensory training, could help children with autism who have trouble processing sensory information. Twenty-six children aged 4 to 12 received 15-minute sessions twice a day, five days a w…

This study tested a tablet application called Mental Imagery Therapy for Autism (MITA) in 150 children aged 2 to 8 with autism. The goal was to see if using the app could improve their language, sociability, and cognitive awareness. Researchers measured changes using standard che…

This study tested whether taking creatine supplements could improve brain health and reduce symptoms in people with autism spectrum disorder (ASD). Twenty participants aged 10 and older took creatine or a placebo for a period. Researchers measured changes in brain creatine levels…

This study tested a mobile app called TRIP designed to support Chinese parents of children with autism. The app provides mindfulness training and parenting tips over 6 weeks. Researchers measured if parents found the app useful and if it helped reduce their stress and anxiety. Th…

This study tested whether occupational therapy that includes horseback riding can help autistic youth improve self-regulation, compared to standard clinic-based therapy. 73 participants received 10 weeks of therapy and provided weekly saliva samples. The goal was to see if the ho…

This study tested a 16-week sensory-friendly physical activity program for autistic children aged 7-12 in special education schools. The program included predictable routines and calming cool-downs to help with sleep. Researchers measured sleep quality using wrist monitors and pa…

This study tested a light therapy called transcranial photobiomodulation (tPBM) to see if it could safely reduce autistic traits and ADHD symptoms in children and teens. 38 participants aged 9 to 17 with ADHD and at least moderate autism symptoms received the treatment. The goal …

This study looked at whether aquatic (water) training or land exercises better improve motor function in children with autism. Forty children aged 3 to 5 with mild to moderate autism took part. Researchers measured changes in motor skills, autism severity, and quality of life aft…

This study tested an online sleep program for preschool-aged children with autism who have trouble sleeping. 20 children participated to see if the program was easy to use and helped improve sleep. The goal was to make sleep help more accessible for families.

This pilot study tested a 14-week Independent Life Skills Program (ILSP) for adults with autism. The program covers personal management, home skills, and community integration through group sessions led by occupational therapists. Thirty adults aged 18 and older with autism and b…

This completed study tested whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) could improve social awareness and reduce repetitive behaviors in 16 adults with autism spectrum disorder. rTMS uses magnetic pulses to gently…

This study tested whether parents can learn a proven autism therapy called Pivotal Response Treatment (PRT) through secure video calls. 101 children aged 2-5 with autism and language delays took part. Parents received weekly 60-minute training for 12 weeks. The goal was to see if…

This study tested a coaching program for families of young children (ages 1.5 to 4.5 years) with suspected or confirmed developmental delays. The program included regular coaching sessions, online education, and peer support over 18 months. Researchers measured whether this appro…

This study tested a time-limited version of Parent-Child Interaction Therapy (PCIT) delivered via telehealth for young children (ages 2-6) with autism and disruptive behavior problems. 80 families were randomly assigned to receive 10 sessions of Tele-PCIT or continue with their u…

This study tested the drug atomoxetine in 60 children with autism who also had significant hyperactivity, inattention, or impulsivity. Over 8 weeks, researchers measured changes in ADHD symptoms using a standard rating scale. The goal was to see if atomoxetine could safely reduce…

This study tested whether omega-3 and omega-6 supplements could improve behavior and reduce inflammation in 98 children aged 2-6 with autism. Researchers measured changes in autism symptoms and certain blood markers over 90 days. The goal was to see if these natural supplements c…

This study tested special safety kits for children with autism who tend to wander away from safe places. Caregivers of 65 children aged 4 to 11 rated how useful each kit item was and how the kits affected their stress and ability to go out in the community. The goal is to use thi…

This study tested whether therapeutic horseback riding can improve behavior, social skills, and emotional control in 250 autistic youth who also have a mental health condition. Participants were randomly assigned to riding, barn activities without riding, or a hybrid group. Resea…

This study tested whether a biofeedback video game called Mightier can help children aged 8-12 with emotional dysregulation. 183 kids were randomly assigned to play the game at home or receive usual care for 6 months. Researchers tracked symptoms, parent stress, and healthcare co…

This study tested whether a noninvasive technique called repetitive transcranial magnetic stimulation (rTMS) could improve cognitive functions and behavior in 35 children with autism spectrum disorder (ASD), aged 5 to 11. The treatment uses magnetic pulses to gently stimulate bra…

This pilot study tested whether lithium can improve social communication in children with autism spectrum disorder who also have a SHANK3 gene mutation (Phelan-McDermid syndrome). 22 children took either lithium or a placebo for 12 weeks. Researchers measured changes in social re…

This study tested different doses of melatonin to see which one best improves sleep quality in autistic children aged 3 to 12 who have trouble sleeping. Researchers measured things like how long it takes to fall asleep, total sleep time, and number of night awakenings using sleep…

This study tested whether a specialized swim program (Sensory Enhanced Aquatics) helps autistic children aged 5-9 learn swimming and water safety better than standard lessons. Fifty-one children participated in 16 half-hour lessons. Researchers measured swimming skills before and…

This study tested whether a robot program can help children with autism spectrum disorder (ASD) better understand emotions and social cues. Forty children aged 4 to 8 were split into two groups: one used the robot program for 8-14 weeks, the other received no extra help. Research…

This study looked at whether a special type of counseling, called the Tidal Model, could help mothers of children with autism. The mothers attended 8 weekly one-on-one sessions. The goal was to reduce feelings of internalized stigma (blaming themselves) and improve their overall …

This study adapts an existing advocacy program, called ASSIST, for Latinx families of autistic youth aged 12 and older. The program teaches parents how to advocate for adult disability services, aiming to improve access to care. Researchers will test the adapted program with 48 S…

This study looked at how adults with autism spectrum disorder (ASD) form emotional attachments to others. Researchers used questionnaires to measure social responsiveness and attachment styles in 32 adults with ASD. The goal was to better understand the link between autism and at…

This study tested a digital app called CICADAS, designed to improve thinking skills in teenagers with autism. Sixty-eight teens aged 11-18 used the app for up to 40 hours, doing exercises that adapt to their ability. The goal was to see if the app is acceptable and easy to use, n…

This study looked at how adults with autism spectrum disorder (ASD) and bipolar disorder (BD) experience and show emotions. Researchers measured things like heart rate, pupil size, and facial expressions in a lab, and also tracked emotions in daily life for a week. The goal was t…

This completed study looked at how adults with autism spectrum disorder (ASD) process emotions in moral situations, compared to people without autism. Researchers used stories about harm and accidents, then asked participants to quickly identify faces or judge if facial expressio…

This study tested whether a 6-session online class called HEARTS helps autistic adults feel more satisfied with their friendships and dating relationships, compared to a 6-week online discussion group. Ninety-two autistic adults took part over three months, completing surveys abo…

This study tested a family navigator program and a smartphone app to help low-resourced families of young children (ages 3-5) with autism find and access services. 52 families took part. The program aimed to improve parents' knowledge, skills, and confidence in getting support fo…

This study looked at how children with autism (without intellectual disability) form and recall paired memories, like linking a face to a name. Researchers used EEG brain scans and memory tests to compare 74 right-handed children aged 10-18, half with autism and half without. The…

This study explored why some children with autism respond better to parent-led therapies than others. Researchers tested different sequences of parent education and child coaching in 81 toddlers (12-36 months) to see which approach worked best for which families. The goal was to …

This study used brain scans like MEG, EEG, and MRI to learn how the brains of people with autism spectrum disorder process sensory information. 85 people between the ages of 14 and 32 took part. The goal was to better understand the condition, not to test a new treatment.

This study created a database of 40 people, including healthy volunteers and those with autism spectrum disorder, to make it easier to recruit for future research. Participants were between 14 and 32 years old. The goal was to build a pool of willing volunteers for upcoming studi…

This study tested a training program for teachers of preschool children with autism. Forty teachers from mainstream schools in Barcelona took part. The program aimed to give teachers practical tools to support children with autism in the classroom. The main goal was to see if tea…

This study looked at the types of bacteria in the mouth and the levels of a protective antibody in the saliva of children with autism, aged 6 to 18. Researchers collected dental plaque and saliva samples to compare with dental health. The goal was to learn more about oral health …

This study followed 344 infants with a sibling diagnosed with autism from birth to age three. Researchers collected blood, stool, urine, and saliva samples to find early biological markers that might predict autism. The goal is to better understand how autism develops and eventua…

This study looked at 15 people with a rare genetic condition called DDX3X syndrome, which can cause intellectual disability and sometimes autism. Researchers used interviews, play-based assessments, and genetic tests to better understand the condition. The goal was to describe th…

This study looked at whether teenagers with autism spectrum disorder can comfortably wear different types of wearable devices—like wristbands, headbands, patches, or rings—for two weeks. Forty teens and their caregivers participated, answering questions and wearing the device as …

This study looked at whether children with autism spectrum disorder (ASD) can learn new words by overhearing conversations, compared to being directly taught. Researchers tested 342 children aged 18 to 71 months, both with and without ASD, using video sessions. They measured lear…

This completed study looked at how teenagers with autism or schizophrenia understand emotions, metaphors, and social situations compared to healthy teens. Researchers tested 60 participants using facial emotion recognition and other tasks. The goal was to find out if social diffi…

This study looked at whether a program called Movement Matters is practical and acceptable for children aged 7-11 with intellectual disabilities or autism. The program includes teacher training, school activities, family involvement, and role models. Researchers worked with 43 ch…

This study looked at new ways to help children with autism who also have severe destructive behaviors, like aggression or self-harm. The goal was to make communication therapy more flexible and prevent bad behaviors from coming back when therapy is interrupted. Nine children aged…

This study tested a 10-week group education program for parents of autistic preschoolers in Türkiye. The program taught naturalistic teaching strategies to help parents support their child's development. Researchers measured changes in parents' confidence and tracked how many fam…

This study created and tested a program called Families FORWARD to help parents of autistic teens (ages 14-21) plan for their child's future. 27 families in Massachusetts took part. The program focused on improving family readiness for the teen's transition to adulthood. Research…

This study looked at gut bacteria in children with autism and their neurotypical siblings who live together. Researchers collected stool samples from 20 children aged 3 to 10. The goal was to compare the types of bacteria and other substances in the gut. This was an observational…

This completed study looked at 500 children aged 5 to 18 to understand how factors around birth, thinking abilities, and social-emotional skills are linked to learning difficulties and developmental disorders like ADHD or autism. Researchers compared children with and without the…

This study looked at how children with autism and typically developing children perform physical tasks like standing still or walking when they also have to do a thinking task at the same time. Researchers tested 90 children aged 5 to 16 using a balance board and a walking app. T…

This study tested JASPER, a play-based therapy for autism, in 84 toddlers aged 18 months to 5 years. Children were randomly assigned to receive JASPER from a clinician or their parent. The goal was to see if two new measurement tools (BOSCC and ELSA-T) could track changes in soci…

This study looked for early signs of epilepsy in children with autism and tested whether a structured exercise program could influence those signs. Fifty children aged 10-15 with autism, epilepsy, or both took part. Researchers analyzed blood, sleep, brain activity, and thinking …

This study looked at how stress-reduction classes affect brain function in adults with autism. 108 participants were randomly assigned to either an 8-week mindfulness program or a relaxation and social support group. Researchers used brain scans and questionnaires to see if chang…

This study tested a program that uses technology and trained family navigators to help children with autism and their families get connected to mental health services more quickly. The program was used in primary care clinics. Researchers measured how acceptable, feasible, and he…

This study looked for brain markers of catatonia (a condition causing movement and behavior problems) in people with autism. Researchers used MRI scans to target a brain area with magnetic stimulation and measured brain activity and symptoms. The goal was to see if overactive bra…

This study used special PET and MRI scans to look at brain activity in 27 men with autism, Fragile X syndrome, or no condition. The goal was to measure a brain chemical called glutamate, which helps nerve cells communicate. Researchers hope this will reveal how brain signaling di…

This study looked at whether the ability to learn patterns (called statistical learning) can predict how well first-graders with autism and their non-autistic peers improve their language and reading skills over three months. Forty-one children completed language tests and comput…

This study tested two types of early help for infants who may develop autism. About 269 families with a baby at higher risk (because an older sibling has autism) took part. Some parents got a web-based guide to support their baby's social communication, and later, some received e…

This study tested a new parent questionnaire called ORALQUEST to assess feeding and eating disorders in children aged 9 months to 6 years. Researchers included 338 children with chronic conditions like heart defects or autism, as well as those with picky eating. The goal was to s…

This study tested whether an online program called Work Chat could be delivered entirely over the internet to autistic adults. Researchers wanted to see if it was practical and if it helped with social skills like understanding hints and emotions. 234 employed or job-seeking auti…

This completed study at the NIH enrolled 96 children with known or suspected genetic disorders, including autism and Fragile X syndrome. The main goal was to give clinic staff hands-on experience and explore new research ideas. Participants received medical exams, lab tests, and …

This study tested a training program to help autistic adults learn to use rideshare services like Uber or Lyft. 13 autistic adults took part to see if the training was acceptable and helpful. The goal was to give them more freedom to travel independently for work, social events, …

This completed study looked at how people with autism spectrum disorder (ASD) pay attention to emotional cues and changes in their environment, compared to people without ASD. Researchers used brain imaging (fMRI, DTI) and EEG to measure brain activity in 120 children and adults.…

This study tested whether a 6-session psychoeducation program could improve autism knowledge, sibling relationships, well-being, and resilience in 88 adult siblings of people with autism. Participants were all neurotypical adults living in Greece. The program was designed to prov…

This pilot study looked at how routine occupational therapy changes brain activity and behavior in children with autism. Two children received weekly one-hour therapy sessions for 6-8 weeks. Researchers used EEG to measure brain responses and parent questionnaires to track social…

This study explores how parents' own language skills influence the quality of early language interactions with their children, especially those with language delays or autism. Researchers trained 156 parents using a program called Enhanced Milieu Teaching, which teaches responsiv…

This completed study looked at how the body processes certain amino acids in people with autism compared to healthy volunteers. Researchers gave participants a special infusion of stable isotopes to track metabolism, and also tested their thinking and mood. The goal was to find l…

This study tested a set of questions to better identify suicide risk in young people aged 8–17 with autism or other neurodevelopmental disorders. Researchers asked 278 participants and their parents about thoughts of self-harm and understanding of death. The goal was to create a …

This study looked at 40 children with autism and 40 healthy children, ages 5 to 10, to see how posture, hand function, and sensory processing affect nutrition. Researchers measured head posture, balance, hand strength, and feeding behaviors. They found that children with autism h…

This study looked at 29 boys with autism, aged 6 to 8, to see if brain scans could reveal how sensory-based occupational therapy changes the brain. Half received a customized 16-week sensory enrichment program, while the other half served as controls. Researchers used MRI before …

This completed study from Yale University enrolled 565 children aged 6-11, both with and without autism, to confirm whether certain brain wave and eye-tracking measures can serve as reliable biomarkers. The goal is to provide objective tools for future clinical trials to measure …

This completed study tested a device called EarliPoint that uses eye-tracking to monitor changes in children with autism spectrum disorder (ASD) or developmental delays. Researchers followed 325 children aged 15-84 months over 180 days to see if the device could detect improvemen…

This completed study used a non-invasive brain stimulation technique called rTMS to investigate how a specific brain area (the superior temporal sulcus) influences social perception in people with autism and healthy controls. Researchers measured changes in eye-gaze patterns and …