Scientists scan brains of people with autism and fragile x to spot key differences

NCT ID NCT02719951

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study used special PET and MRI scans to look at brain activity in 27 men with autism, Fragile X syndrome, or no condition. The goal was to measure a brain chemical called glutamate, which helps nerve cells communicate. Researchers hope this will reveal how brain signaling differs in these conditions.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
[18F]FPEB (a radioactive tracer for PET scans)
What this could lead to
If successful, this could help researchers better understand brain chemistry differences in autism and Fragile X syndrome.
What could go wrong
This is a small, early-phase imaging study, not a treatment trial. It may not lead to direct benefits for patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Tours

    Tours, 37044, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.