Scientists scan brains of people with autism and fragile x to spot key differences

NCT ID NCT02719951

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study used special PET and MRI scans to look at brain activity in 27 men with autism, Fragile X syndrome, or no condition. The goal was to measure a brain chemical called glutamate, which helps nerve cells communicate. Researchers hope this will reveal how brain signaling differs in these conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

[18F]FPEB (a radioactive tracer for PET scans)

What this could lead to

If successful, this could help researchers better understand brain chemistry differences in autism and Fragile X syndrome.

What could go wrong

This is a small, early-phase imaging study, not a treatment trial. It may not lead to direct benefits for patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autism autism spectrum disorder fragile X syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Tours

    Tours, 37044, France