ANESTHESIA

This study tested two medications, norepinephrine and phenylephrine, to prevent low blood pressure during C-sections with spinal anesthesia. 98 women took part. Norepinephrine was more effective, causing fewer cases of low blood pressure and a steadier heart rate. Both drugs were…

This study tested whether giving each patient a personalized blood flow target during major abdominal surgery could lower the risk of serious complications like kidney injury, heart damage, infections, and death. Over 1,100 high-risk adults (aged 45+) took part. The approach used…

This study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of wound infections after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if this simple, low-cost approach could improve reco…

This study tested whether injecting numbing medicine around (instead of into) the nerve bundle in the neck could lower the chance of severe "rebound pain" after shoulder surgery. Rebound pain is a short but intense pain that can happen as the nerve block wears off. The study invo…

This study tested two ways of giving epidurals for labor pain: the standard method and a newer technique called dural puncture epidural. The goal was to see which one needed fewer extra pain-relief injections from a doctor during early labor. 130 healthy pregnant women took part,…

This study looked at two common ways to calm children before an endoscopy: a calming nose spray (dexmedetomidine) or watching short videos. Researchers measured anxiety levels in 50 children aged 2-12 at different times before the procedure. The goal was to see which method worke…

This study tested whether avoiding morphine during heart surgery could lower the risk of serious complications like breathing trouble, confusion, and gut paralysis. 268 adults having planned heart surgery were randomly assigned to receive either standard morphine-based anesthesia…

This study tested if using a special laser before applying numbing gel (lidocaine) can reduce pain during dental procedures. Twenty adults were split into three groups: laser plus numbing gel, fake laser plus numbing gel, or fake laser plus plain Vaseline. Researchers measured pa…

This study tested a newer sedative drug, remimazolam, against the standard drug propofol for people having a heart ultrasound called a TEE. The goal was to see if remimazolam could keep blood pressure and heart rate more stable during the procedure. 105 adults took part, and rese…

This study compared two types of nerve blocks (PENG and SFIC) to see which provides better pain relief for people undergoing hip replacement surgery. 100 adults aged 40 and older took part. The goal was to find a method that works faster and reduces the need for strong painkiller…

This study looked at whether a sedative called dexmedetomidine, given through a vein, can prevent sudden rises in blood pressure and heart rate when a breathing tube is inserted. It involved 70 adults with controlled high blood pressure who were having planned surgery under gener…

This study looked at whether giving patients their pain medication prescription before surgery (during the anesthesia check-up) leads to less pain at home after day surgery compared to giving the prescription after surgery. About 200 adults having day surgery with general anesthe…

This study tested two different IV drug combinations used to sedate people during wisdom tooth removal. 73 patients received either a mix of nitrous oxide, midazolam, fentanyl, and ketamine, or the same mix with propofol instead of ketamine. Researchers measured how quickly patie…

This study tested a special app called PIRA that teaches children ages 4 to 10 about surgery in a fun, interactive way. Researchers wanted to see if using the app before an operation would lower anxiety in kids and their parents, and help kids wake up more calmly from anesthesia.…

This study tested a new drug called HSK3486 to see if it works well for putting adults to sleep before planned surgery. About 255 people took part, and the drug was compared to a standard anesthesia drug, propofol. The main goal was to see how many people had a smooth and success…

This study tested two pain relief methods after hip replacement surgery: a continuous nerve block near the spine (erector spinae plane block) versus standard epidural pain relief. Researchers measured pain levels, opioid use, muscle strength, walking ability, and quality of recov…

This study tested whether an ultrasound-guided TAP block (a type of nerve block) can reduce pain and improve stability during a heart valve replacement procedure called TAVI. Fifty adults undergoing elective TAVI received either the block or standard care. The goal was to see if …

This study looked at whether a special nerve block (erector spinae plane block) could help people use fewer strong painkillers after breast reduction surgery. 78 adults took part. The goal was to see if adding this block to standard pain care reduces opioid use and side effects l…

This study tested three different liquid sedatives (dexmedetomidine, ketamine, and midazolam) to see which one works best for calming children aged 3 to 7 before inguinal hernia surgery. Sixty children took part, and researchers measured how sleepy they became and their pain afte…

This study tested whether using two types of nerve blocks together (paravertebral and serratus plane blocks) works better than just one for pain control after video-assisted lung surgery. 112 adults aged 18 to 75 took part. The main goal was to see if the double block reduces the…

This study looked at whether adding an extra nerve block (called iPACK) to the usual pain management during ACL knee surgery can lower the need for strong painkillers (opioids) after the operation. About 90 adults having ACL repair were randomly assigned to receive either the sta…

This study looked at whether using a fast-acting opioid called remifentanil during general anesthesia for emergency C-sections is safe for premature babies. It involved 53 mothers and their newborns. The main goal was to see if the babies had healthy Apgar scores (a measure of ne…

This study looked at whether teaching women about pain before a planned hysterectomy could help lower their anxiety, stress, and pain after surgery. 62 women took part. The approach included a special pre-anesthesia checkup and pain education. The goal was to see if this extra pr…

This study compared two ways of giving methadone pain medication to patients having elective heart surgery. Researchers tested whether taking methadone as a pill before surgery works as well as getting it through an IV during anesthesia. The goal was to see which method provides …

This study looked at whether a non-invasive monitor called the Nociception Level (NoL) index can measure pain in children under general anesthesia. Researchers gave 30 children aged 5-12 mild electrical shocks of different strengths before surgery and recorded the NoL index chang…

This study looked at how two different hand muscles recover from muscle relaxants given during surgery. In 57 patients, researchers compared the recovery time of a thumb muscle versus a pinky muscle using standard monitors. The goal was to see if one muscle gives a better sign of…

This study looked at whether a special brain monitor (4-channel EEG) can help doctors give just the right amount of sedation during a procedure called ERCP. 84 adults took part, and the goal was to see if using the monitor led to using less sedative medicine and helped patients w…

This study tested a faster way to give anesthesia medicines before placing a breathing tube. It compared giving two drugs at once versus the usual step-by-step method. The goal was to see which approach allows doctors to place the tube more quickly and safely. The study involved …

This study looked at whether patients can effectively give themselves extra oxygen (preoxygenation) before surgery by holding the mask themselves, instead of having a doctor or nurse do it. The study included 110 adults scheduled for surgery under general anesthesia. Researchers …

This study looked at whether giving spinal anesthesia quickly (15 seconds) or slowly (90 seconds) changes blood pressure and heart function in elderly patients with a broken hip. Eighty-four patients over age 65 took part. Researchers measured blood pressure and other heart measu…

This study tested whether giving a small amount of fluid (3 ml per kg over 2 minutes) can predict if a child under anesthesia will need more fluids. 60 children having scheduled surgery took part. The goal was to avoid giving too much fluid, which can be harmful. The approach was…

This study looked at 72 adults having surgery under general anesthesia to compare two airway devices: a classic glottis mask airway and a tulip-shaped one. The goal was to see which device leads to less stomach acid backing up into the throat during breathing support. Researchers…

This study looked at how a low dose of the anesthetic sevoflurane, combined with short-term pain, affects memory and automatic body responses. Forty-two healthy adults took part in two sessions, including brain scans. The goal was to understand the brain processes involved, not t…

This study looked at how the brain responds to pain and sound while a person is under general anesthesia. Researchers used a special light-based technique called near-infrared spectroscopy to measure blood flow changes in the brain. 44 healthy volunteers aged 12-30 took part. The…

This study looked at 332 people having a procedure to remove a blood clot from the brain after a stroke. Researchers wanted to see if using sedation (keeping the patient sleepy but breathing on their own) or general anesthesia (being fully asleep with a breathing tube) led to bet…

This study looked at 485 patients who had coronary artery bypass surgery to see if a computer method called fuzzy logic could better predict who might die after the operation. Fuzzy logic mimics human reasoning to handle uncertain information, like a doctor's experience. The goal…

This study followed 204 adults who had a kidney removed to find out why some develop chronic pain lasting months or years. Researchers measured pain levels right after surgery, at 3 months, and at 1 year. They also looked at factors like age, smoking, and pain medicine use to ide…

This study compared two methods—CoolStick and ethyl chloride spray—for checking how well the anesthesia is working before a C-section. 64 pregnant women having planned C-sections took part. The goal was to see which tool better measures numbness to light touch and cold. This rese…

This study looked at a new method to set breathing machines for children under anesthesia. Instead of using a fixed breath size, researchers measured the air that actually reaches the lungs (alveolar ventilation) using a special device. The goal was to find a steady target that k…

This study looked at how small air sacs in the lungs (called alveoli) collapse in children aged 1 to 6 during anesthesia for MRI scans. Researchers used a special imaging technique to measure these changes before and after the procedure. The goal was to better understand how anes…

This study tested a new portable device called MARIE that measures carbon dioxide (CO2) in the breath of 40 adults after surgery. The goal was to see if MARIE works as well as standard hospital monitors to detect breathing problems early. Researchers compared MARIE's readings wit…

This study looked at how different types of anesthesia affect eye pressure and the optic nerve during kidney stone surgery. Sixty adults having the surgery were randomly assigned to receive either minimal low-flow or high-flow anesthesia. The goal was to see which method is safer…

This study looked at how doctors prescribe sugammadex, a drug that reverses muscle relaxants after surgery, in everyday hospital practice. Over 6,400 adults having planned surgeries were observed for 24 hours after receiving the drug. The goal was to see how often it was given ag…

This study looked at whether mental training can lower stress in anesthesia residents before they perform epidural pain relief for childbirth. 32 residents in training were randomly assigned to either do mental preparation or not, and their stress levels were measured. The goal w…

This study compared two methods for placing a special breathing tube (double-lumen tube) used in lung surgery. Over 900 adults having thoracic surgery were randomly assigned to get the tube placed using either a traditional laryngoscope or a video laryngoscope. The main goal was …

This study looked at whether checking patients by phone before surgery leads to more cancellations than checking them in person. Researchers reviewed records of 1,176 adults scheduled for non-cardiac surgery at two hospitals. The goal was to see if phone assessments are a safe an…

This study looked at whether a gentle electrical stimulation at specific acupoints (Neiguan and Shenmen) can help prevent delirium—sudden confusion—after abdominal surgery in patients aged 65 and older. The researchers also checked brain wave patterns to understand how it might w…

This study looked at over 3,600 adults having major surgery to find out which of two blood pressure drugs (norepinephrine or phenylephrine) is better at preventing serious problems like kidney injury or death. Patients received one of the drugs during anesthesia, and researchers …

This study created a new monitoring system that combines brain waves, oxygen levels, blood pressure, and heart rate to help doctors give the right amount of anesthesia during surgery. The goal was to avoid giving too much or too little anesthesia, which can be dangerous. The syst…

This study tested two devices that measure pain in children aged 1 to 12 during surgery. The goal was to see how well they detect pain signals. Fifty children took part, and the results help doctors choose better pain monitors for young patients.

This study tested a new way to remove carbon dioxide (CO2) from the air patients breathe during anesthesia, without using chemical filters. Current chemical filters can create harmful compounds, increase costs, and create environmental waste. The trial included 286 low- to medium…

This study tested three different breathing tube devices (GMA-Tulip, i-gel, and LMA-Supreme) in 498 adults having surgery under general anesthesia. Doctors checked how well each device allowed them to see the airway and maintain safe breathing. The goal was to find which device w…

This study looked at whether video calls (teleconsultations) could replace in-person visits for children needing anesthesia during the COVID-19 pandemic. Researchers checked how often these video visits failed and had to switch to a phone call or in-person meeting. The goal was t…

This study looked at 120 children with glaucoma or suspected glaucoma who needed eye exams under anesthesia. The goal was to see if a standard anesthesia protocol helps get consistent and reliable eye pressure measurements. Researchers measured how deep the anesthesia was and com…

This study looked at whether a quick nap (under 30 minutes) can help sleep-deprived anesthesiology residents perform better during stressful situations. 44 doctors-in-training took part in high-fidelity simulations after night shifts. Researchers measured their technical and team…

This study looked at 172 patients in the intensive care unit after surgery who needed insulin. Researchers compared two different methods of giving insulin to see which one caused fewer ups and downs in blood sugar levels. The goal was to find out if using a separate line for ins…

This study used brain imaging to understand how a low dose of the sedative dexmedetomidine reduces pain. Seventeen healthy adults received the drug while researchers measured changes in brain fluid flow. The goal was to learn more about the drug's pain-relieving effects, not to t…

This study tested whether alerts in electronic medical records can help anesthesia providers reduce the amount of fresh gas they use during surgery. Over 300 providers participated, and researchers measured changes in gas flow over 90 days. The goal was to improve efficiency and …

This study looked at whether a video call (telemedicine) is as good as an in-person visit for checking a patient's health before surgery. 172 adults scheduled for surgery at a French hospital took part. Researchers compared how well each method assessed surgical risk, reviewed me…

This study used non-invasive monitors to track heart rate, brain oxygen, and brain waves in 60 patients undergoing carotid surgery or stroke treatment. When surgeons temporarily clamped the carotid artery, the devices recorded the changes. The data will train artificial intellige…

This study looked at 320 adults who had heart surgery to see how well two risk scores (EuroSCORE-II and POSPOM) predict death in the hospital. Researchers used past medical records and did not give any new treatments. The goal is to find out which score is more reliable for plann…

This study looked at how the brain processes visual information while under anesthesia. Researchers also tested if using ultrasound on the brain could help people wake up faster after being sedated. 36 healthy adults took part in this Phase 2 trial at the University of Michigan.

This study looked at 153 people having liver surgery for cancer to see if the type of anesthesia they received affected their immune response and long-term outcomes. Researchers compared different anesthesia methods and measured blood markers related to immune activity. The goal …

This study tested whether a device that delivers warm, moist oxygen through the nose (Optiflow) could replace the traditional face mask during the start of anesthesia. Sixty adults having surgery with general anesthesia took part. The goal was to see if this method could make the…

This study looked at how well BD NRFit spinal needles and syringes work in real medical settings. 161 patients of any age who needed a spinal procedure took part. Researchers measured how often the needle was placed correctly, how well the syringe worked, and if there were any si…

This study tested whether giving 50% or 100% oxygen during breathing tube removal after general anesthesia leads to fewer drops in oxygen levels. 119 adults having various surgeries took part. The goal was to find the safest oxygen amount to prevent complications like low oxygen …

This study examined 348 adults who had open heart surgery with a heart-lung machine. Researchers looked at the ratio of time on the machine to time the heart was stopped to see if it affected complications. The goal was to better understand how these timing factors relate to reco…

This study tested whether a PENG block (a type of nerve block) can reduce inflammation and improve survival in 60 older adults (over 65) having hip fracture surgery. Researchers measured blood markers of inflammation and tracked deaths within 30 days. The goal was to see if this …