ANESTHESIA

This completed Phase 3 study tested whether a new drug called HSK3486 works as well as the standard drug propofol for putting adults to sleep before planned surgery. Researchers compared how effectively each drug induced anesthesia and monitored side effects like injection pain. …

This study aimed to find out which of two common medications is better for maintaining a patient's blood pressure during major surgery. Researchers compared norepinephrine and phenylephrine in over 3,600 adults undergoing long operations to see which drug led to fewer serious com…

This study tested a new device called memsorb that filters carbon dioxide from the breathing circuit during anesthesia, instead of using chemical granules. The goal was to see if it works as well as current methods while potentially being safer and better for the environment. It …

This study compared two techniques for placing a special double-lumen breathing tube in patients undergoing lung surgery. Researchers tested whether using a video laryngoscope (which shows the airway on a screen) was more successful on the first try than the traditional direct la…

This large international trial tested whether customizing a patient's blood flow target during major abdominal surgery reduces serious complications afterward. It involved over 1,100 high-risk patients aged 45 and older. The goal was to see if aiming for a patient's own pre-surge…

This large international study tested whether tranexamic acid (TxA), a drug commonly used to reduce bleeding during surgery, could also help prevent wound infections and other complications after major gastrointestinal operations. It involved 3,300 adult patients at higher risk f…

This study looked at whether the type of anesthesia used during liver cancer surgery influences a patient's recovery and long-term health. Researchers compared four different anesthesia methods in 153 patients to see if they affected inflammation, pain medication needs, and cance…

This study aimed to create a standard anesthesia method for children who need eye exams for glaucoma. Young children often can't stay still for these important pressure checks, so they must be put to sleep. Researchers tested if using a specific, safe anesthesia plan would lead t…

This study compared two tools doctors use to check if a patient is numb enough before a planned C-section. Researchers tested a reusable metal CoolStick against the standard ethyl chloride spray on 64 patients. The goal was to see if the CoolStick works just as well for checking …

This study tested a new portable device called MARIE that monitors a patient's breathing after surgery. Researchers compared it to standard hospital equipment to see if it accurately measures carbon dioxide levels and breathing rate. The goal is to see if this smaller, simpler de…

This study tested a new monitoring system designed to help anesthesiologists better track how deeply a patient is asleep during surgery. It combined measurements of brain waves, oxygen levels, heart rate, and blood pressure using computer algorithms. The goal was to create a tool…

This study tested a new method to help anesthesiologists decide how much fluid to give children during surgery. Researchers checked if a very small, quick fluid dose (3 ml/kg) could accurately predict how a child's heart would respond to the standard, larger fluid dose (15 ml/kg)…

This study compared two sedation drugs (remimazolam and propofol) used during a heart ultrasound test called a TEE. Researchers wanted to see if the newer drug, remimazolam, worked as well as the standard drug but caused fewer drops in blood pressure. The study involved 105 adult…

This study compared three different oral sedative medicines given to children before hernia surgery. The goal was to see which drug helped kids feel calmer before the procedure and which led to less pain and distress afterwards. The study involved 60 children aged 3 to 7 years.

This study looked at whether it's better to give patients their pain medication prescription before or after outpatient surgery. It involved 200 adults having day surgery under general anesthesia. The goal was to see which timing leads to less pain at home after the operation.

This study tested whether short 'power naps' could help tired anesthesiology residents perform better during simulated medical emergencies. Researchers recruited 44 residents who worked night shifts and got little sleep. They compared the performance of residents who took a short…

This study tested whether providing education about pain and a pre-surgery check-up could help reduce anxiety, stress, and pain for women undergoing a planned hysterectomy. Researchers worked with 62 women having this surgery at a hospital in Mexico. They compared outcomes betwee…

This study tested if a targeted nerve block in the abdomen could better control pain for patients undergoing a minimally invasive heart valve replacement (TAVI). The goal was to keep patients more comfortable and still during the procedure, which may improve safety and satisfacti…

This study tested a new way to give anesthesia drugs to help place a breathing tube more easily at the start of surgery. Researchers compared this new method to the standard approach in 154 patients who were overweight or had potentially difficult airways. They measured how quick…

This study tested if a gentle electrical stimulation on specific wrist and ear acupoints could reduce confusion (delirium) in older adults after major abdominal surgery. Researchers enrolled 226 patients to see if this non-drug method could lower delirium rates and improve recove…

This study tested if a specific way of giving a numbing nerve block could reduce severe 'rebound pain' that sometimes hits patients after shoulder surgery wears off. Researchers compared two injection techniques in 85 adults having arthroscopic shoulder surgery. The goal was to s…

This study tested whether using a special brain monitor (a 4-channel EEG) could help doctors better manage sedation during a complex digestive procedure called ERCP. The goal was to give patients the right amount of anesthesia to keep them safe and comfortable, potentially leadin…

This study tested if adding a specific back nerve block to standard pain control methods could reduce the need for opioid painkillers after breast reduction surgery. Researchers compared patients who received the nerve block with those who did not, measuring pain levels and opioi…

This study compared two common medications used to prevent a dangerous drop in blood pressure during spinal anesthesia for planned cesarean sections. In 98 women, a continuous infusion of norepinephrine was significantly more effective than phenylephrine at maintaining stable blo…

This study compared two different nerve block methods for managing pain during and after hip replacement surgery. Researchers tested whether a newer technique called the PENG block works as well as a more established method called the SFIC block. The goal was to find which approa…

This study looked at two common ways to help children feel less anxious before a stomach or colon exam (endoscopy). Researchers compared letting kids watch short videos to giving them a calming nasal spray. They measured how anxious the kids were, how much sedation medicine they …

This study tested whether a special interactive video chat tool could help reduce anxiety for children and their parents before surgery. Researchers compared the tool to the standard educational materials hospitals usually provide. They measured anxiety levels in the waiting room…

This small, early study tested if a special dental laser could make numbing gel work better. Researchers wanted to see if using the laser before the gel would reduce pain and keep patients calmer during a simulated dental procedure. They compared the laser plus gel against a fake…

This study tested whether adding a specific nerve block (called iPACK) to standard pain control improves recovery after ACL knee surgery. Researchers compared two groups of 90 adults having surgery: one received the combined nerve blocks, while the other received the standard blo…

This study looked at whether a specific nerve block, given before hip fracture surgery to patients over 65, could help control the body's inflammatory response and improve recovery. Researchers compared two groups: one received the nerve block, and the other received standard pai…

This study compared whether taking methadone as a pill before surgery works as well as getting it through an IV drip during surgery for managing pain after heart operations. It involved 41 patients having scheduled heart surgery. Researchers measured pain levels and how much addi…

This study aimed to teach a computer program how to recognize when the brain isn't getting enough blood. Researchers monitored 60 patients during planned surgeries where blood flow to the brain was briefly reduced. They used non-invasive devices to track heart rate, brain oxygen …

This study looked at whether giving spinal anesthesia slowly (over 90 seconds) causes less of a drop in blood pressure compared to giving it quickly (over 15 seconds) in elderly patients having hip fracture surgery. Researchers monitored 84 patients' heart and blood pressure func…

This study compared how two different hand muscles recover from anesthesia drugs used during surgery. Researchers monitored 57 patients to see if the muscle at the base of the thumb recovers differently from the muscle at the base of the little finger. The goal was to gather info…

This study compared two different shapes of airway masks used to help patients breathe during surgery under general anesthesia. Researchers wanted to see if a newer 'tulip-shaped' mask was better than the standard design at preventing stomach acid from leaking up into the throat,…

This study tested whether a mental preparation session could help reduce stress for anesthesia residents before they perform a common but high-pressure procedure: placing an epidural for a woman in labor. Thirty-two residents were randomly assigned to either receive the mental tr…

This study looked at whether doctors could successfully plan for children's anesthesia using video calls instead of in-person visits during the COVID-19 pandemic. Researchers wanted to see if this remote method was practical and worked well for families and medical teams. The goa…

This study looked at whether using a specific, short-acting pain medication (remifentanil) for mothers during emergency C-sections for premature births is safe for the baby's first critical minutes. Researchers compared babies whose mothers received this medication to those whose…

This study aimed to understand how a low dose of the sedative drug dexmedetomidine relieves pain by looking at brain activity. Researchers gave the drug to 17 healthy volunteers and used MRI brain scans while applying a controlled pain stimulus. The goal was to map how the drug c…

This study compared two anesthesia methods during kidney stone removal surgery to see how they affect eye pressure and blood flow. Researchers studied 60 patients having kidney stone surgery to determine whether low-flow or high-flow anesthesia better protects eye health during t…

This study looked back at past patient records to compare two different risk calculators. Researchers wanted to see which tool—EuroSCORE-II or POSPOM—was better at predicting the chance of a patient dying in the hospital after major heart surgery. The study involved 320 adults wh…

This study aimed to understand why some people develop long-lasting pain after kidney removal surgery. Researchers followed 204 patients for a year, tracking their pain levels and many personal and surgical details. The goal was to identify which factors increase the risk of chro…

This study compared three different types of breathing tubes used to help patients breathe during surgery under general anesthesia. Researchers looked at how well each tube worked and recorded side effects like sore throat or hoarseness. The goal was to gather information to help…

This study observed whether it is effective and helpful for patients to hold their own oxygen mask before receiving general anesthesia for surgery. Researchers enrolled 110 healthy or mildly ill patients to see if this 'self-preoxygenation' successfully prepared their bodies with…

This study aimed to understand how the brain responds to pain while a patient is under general anesthesia. Researchers used a special light-based scanner on the heads of 44 young patients undergoing heart procedures to measure blood flow changes in the brain during painful moment…

This study observed over 6,400 surgery patients to see how doctors use a drug called sugammadex, which helps reverse muscle paralysis from anesthesia. Researchers tracked how often the drug was given, how well it worked to restore muscle strength, and what side effects occurred. …

This study tested a new way to set breathing machines for children during surgery and intensive care. Researchers measured the actual air reaching children's lungs to see if this gives better guidance than current methods. The goal was to gather information to help doctors use sa…

This study aimed to understand how the brain processes information at the edge of consciousness during anesthesia. Researchers used brain scans (fMRI) on 36 healthy volunteers while they were given the anesthetic drug propofol. They tested whether a form of ultrasound brain stimu…

This study observed how well a new type of spinal needle and syringe system works during real-world anesthesia procedures. Researchers followed 161 patients for about 10 days after their spinal injections to see how successfully the needles were placed and to check for side effec…

This study tested whether a video call consultation with an anesthesiologist before scheduled surgery is as effective as a traditional in-person visit. Researchers compared the two methods for 172 patients to see if they collected the same quality of information about patient hea…

This study aimed to understand if a specific ratio of two key surgical times could predict complications after open heart surgery. Researchers observed 348 patients undergoing planned, on-pump heart surgery. They measured the time the heart-lung machine was used versus the time t…

This study aimed to test and compare two devices designed to measure pain in children during surgery while they are under general anesthesia. Researchers observed 50 children aged 1 to 12 years old to see how well the devices detected painful events and responded to pain medicati…

This study aimed to create a better tool for predicting which patients are at highest risk during and after heart bypass surgery. Researchers analyzed the medical records of 485 patients who had the surgery. They used a special computer method called 'fuzzy logic' to build a risk…

This study aimed to understand how a low dose of the anesthetic gas sevoflurane affects how the brain processes pain and forms memories. Researchers used MRI brain scans on 42 healthy volunteers while they performed memory tasks and experienced mild pain, both with and without th…

This study tested if a special monitor, which measures a 'nociception level' (NoL), works the same way in children as it does in adults. Researchers used small, controlled electrical stimulations on 30 children aged 5-12 who were under general anesthesia for elective surgery. The…