Which drug combo works best for Pain-Free tooth pulls?
NCT ID NCT06867068
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed pilot study tested two different IV drug combinations used to sedate people during wisdom tooth removal. One combo used ketamine, the other used propofol instead. Researchers measured how quickly patients recovered, whether they remembered the procedure, and how satisfied both patients and surgeons were. The goal was to gather early data to design a larger, more definitive trial.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Midazolam, fentanyl, ketamine, propofol, and nitrous oxide
What this could lead to
If this pilot shows one combo is better, it could lead to a larger trial that helps doctors choose the best sedation for wisdom tooth removal.
What could go wrong
This is a small, early-phase pilot study (73 people) meant only to gather preliminary data. It cannot yet prove which combo is safer or more effective.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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NYCHHC - Jacobi Medical Center and North Central Bronx Hospital
The Bronx, New York, 10461, United States