Which drug combo works best for Pain-Free tooth pulls?

NCT ID NCT06867068

Completed Symptom relief Sponsor: Albert Einstein College of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed pilot study tested two different IV drug combinations used to sedate people during wisdom tooth removal. One combo used ketamine, the other used propofol instead. Researchers measured how quickly patients recovered, whether they remembered the procedure, and how satisfied both patients and surgeons were. The goal was to gather early data to design a larger, more definitive trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Midazolam, fentanyl, ketamine, propofol, and nitrous oxide
What this could lead to: If this pilot shows one combo is better, it could lead to a larger trial that helps doctors choose the best sedation for wisdom tooth removal.
What could go wrong: This is a small, early-phase pilot study (73 people) meant only to gather preliminary data. It cannot yet prove which combo is safer or more effective.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA TOOTH EXTRACTION

Contacts and locations

Locations

NYCHHC - Jacobi Medical Center and North Central Bronx Hospital

The Bronx, New York, 10461, United States

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