Can a natural compound help preserve jawbone after tooth loss?

NCT ID NCT07765745

First seen Aug 14, 2026 ยท Last updated Aug 14, 2026

Summary

This trial tests whether a gel made from thymoquinone, a compound found in black seed oil, can help preserve bone density and width in the jaw after a tooth is removed. Adults aged 18 to 50 who need an upper back tooth extracted may participate. Participants will receive either a standard gel foam, a thymoquinone gel, or a nano-formulated thymoquinone gel placed in the socket, and bone changes will be tracked with 3D imaging.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
0.2% thymoquinone gel (including a nano-formulated version), applied to the tooth socket after extraction
What this could lead to
If it works, this could point toward a simple, natural way to preserve jawbone shape and density after tooth removal, potentially improving healing and future dental implant success.
What could go wrong
This is a small, early-stage trial, so results may not be conclusive or widely applicable. The gel is experimental and its effectiveness and safety are not yet established.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Kafrelsheikh University

    RECRUITING

    Kafr ash Shaykh, Kafrelsheikh, 33516, Egypt

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