Can a tiny dose of ketamine make anesthesia more stable?
NCT ID NCT06986109
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether adding a small amount of ketamine to standard propofol anesthesia helps keep patients at a consistent depth of sedation during laparoscopic surgery. 106 adults were randomly assigned to receive either ketamine or a placebo (salt water) alongside propofol delivered by an automated system. The goal was to see if the ketamine group spent more time within the target sedation range.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ketamine
What this could lead to
If it works, this could lead to more stable anesthesia during surgery, potentially reducing risks from fluctuating sedation levels.
What could go wrong
This is a small, completed study with 106 participants. Earlier research using a different monitoring system found no benefit, so results may not change practice.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Sir Ganga Ram Hospital
New Delhi, National Capital Territory of Delhi, 110060, India