Can a tiny dose of ketamine make anesthesia more stable?
NCT ID NCT06986109
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether adding a small amount of ketamine to standard propofol anesthesia helps keep patients at a consistent depth of sedation during laparoscopic surgery. 106 adults were randomly assigned to receive either ketamine or a placebo (salt water) alongside propofol delivered by an automated system. The goal was to see if the ketamine group spent more time within the target sedation range.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ketamine
- What this could lead to
- If it works, this could lead to more stable anesthesia during surgery, potentially reducing risks from fluctuating sedation levels.
- What could go wrong
- This is a small, completed study with 106 participants. Earlier research using a different monitoring system found no benefit, so results may not change practice.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sir Ganga Ram Hospital
New Delhi, National Capital Territory of Delhi, 110060, India
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