ANESTHESIA

This study tests whether applying mild electrical stimulation to specific acupoints (Neiguan and Jian Shi) for 30 minutes before anesthesia can help prevent low blood pressure in adults over 65 undergoing surgery. Researchers will compare high-frequency versus low-frequency stimu…

This study tests whether a newer anesthesia drug, remimazolam, combined with alfentanil, is safer than the standard propofol combination for chest surgery. The goal is to see if it lowers the chance of low oxygen levels and low blood pressure during the procedure. About 50 adults…

This study compares a special 'multimodal' anesthesia method to standard anesthesia for people having robotic kidney cancer surgery. The goal is to see if the new approach helps patients leave the hospital earlier and feel less pain after surgery. About 80 adults who are candidat…

This study tests whether a numbing injection (retrolaminar block) given before lumbar spine fusion surgery can lower the amount of strong painkillers (opioids) needed afterward. About 44 adults will be randomly assigned to receive either the real block or a fake one. The main goa…

This study tests a new device called SafeLM™, a video-guided breathing mask, in 60 children having surgery. The goal is to see how easy it is to place, how well it seals the airway, and if it causes any problems. The results will help doctors choose better tools for managing chil…

This study tests whether a new combination of sedative and painkiller drugs can make deep sedation safer for elderly patients (ages 60-90) undergoing a procedure called ERCP, which treats bile duct problems. The goal is to reduce breathing complications and speed up recovery comp…

This study compares three different drug combinations used to sedate people during an upper GI endoscopy (a camera down the throat). The goal is to see which combination helps patients fall asleep fastest and wake up quickest afterward. 75 adults aged 18 to 65 who are scheduled f…

This study looks at whether drawing different colors and shapes can help lower anxiety in adults waiting for surgery. About 175 people scheduled for elective surgery will be asked to draw while they wait. Researchers will measure their anxiety levels using simple questionnaires a…

This early study tests whether a medicine called dexmedetomidine, given as a drink, can safely and effectively sedate children aged 3-6 for MRI scans. The goal is to find a dose that avoids serious side effects and produces clear images. If successful, it could offer a gentler al…

This study tests whether gentle electrical stimulation on acupoints can reduce stomach acid backing up into the throat during anesthesia with an i-gel breathing tube. About 116 adults having surgery will be randomly assigned to get the stimulation or not. The goal is to see if th…

This study aims to see which of two common spinal anesthesia drugs helps patients recover faster after outpatient knee replacement surgery. Researchers will compare chloroprocaine and mepivacaine to see which allows patients to move their legs and be discharged from the hospital …

This study looks at how two different ways of giving anesthesia gas (low-flow vs normal-flow) affect the heart's electrical signals in 128 adults having gallbladder surgery. The goal is to see if one method is safer for heart rhythm. Participants will have their heart activity mo…

This study will ask 1000 adults in Danish public hospitals what matters to them before they receive anesthesia for surgery. Participants will fill out a survey on the day of their operation, and some will be interviewed afterward. The goal is to understand current practices and h…

This study looks at whether a video call (teleconsultation) works as well as an in-person visit for checking pregnant women before they receive anesthesia during delivery. About 250 first-time mothers will take part. The goal is to see if the quality of the check-up is similar an…

This study looks back at medical records of 300 adults who had a minor leg amputation (at or below the ankle) to see if the type of anesthesia they received affected their recovery. The goal is to compare general anesthesia (being fully asleep) with regional nerve blocks (numbing…

This study tests whether using a special device (bioelectrical impedance analysis) to guide fluid management can lower the risk of death within 28 days for patients in the intensive care unit after major surgery. About 80 adults will be randomly assigned to either the new fluid g…

This study surveys 200 healthcare professionals (doctors, nurses, and students) to find out which techniques they use when removing a breathing tube after a patient has been on a ventilator. The goal is to describe current practices, since there is no clear agreement on the best …

This study watches brain activity (EEG) in 330 people during routine anesthesia or sedation to see how it relates to drug levels and patient responses. It includes children (some with autism), adults over 70, and adults having sedation for endoscopy. No treatments are changed—the…

This study watches brain activity in 300 adults during high-risk surgeries like heart or spine operations. Researchers use special monitors to track brain waves and pressure, linking them to patient outcomes. The goal is to understand why some people develop confusion or brain in…

This study looks at how lidocaine, a common numbing medicine, affects the electrical signals used to monitor nerves during spine surgery. 44 adults having spine surgery will get either lidocaine or a placebo through an IV. The goal is to see if lidocaine changes the threshold nee…

This study looks at 70 men having robot-assisted prostate cancer surgery. It compares two low gas flow settings (1 liter vs 0.5 liter per minute) for the anesthesia drug sevoflurane. The goal is to see which flow keeps breathing and blood gases more stable during the operation. R…

This study looks at whether adding visual aids to the standard written consent form helps patients better understand anesthesia information. About 236 adults scheduled for elective surgery will either get the usual consent form or one with pictures. Thirty minutes later, their un…

This study tests whether an artificial intelligence (AI) app can improve follow-up for patients who receive continuous pain relief after surgery. About 166 adults will use either the AI app or a standard automated messaging app. The goal is to see if the AI app reduces the number…

This study looks at why some older adults experience confusion or memory problems after major surgery. Researchers will test memory and collect blood samples from 40 patients aged 70 and older before and after colorectal or urological surgery. The goal is to see if these research…

This study will measure certain brain chemicals and thinking abilities in 160 adults having gallbladder surgery. Half have never had general anesthesia before, and half have had it at least once. Researchers want to see if multiple anesthesia exposures are linked to changes in br…

This study will observe 15,000 adults having heart surgery at hospitals worldwide. Researchers will track different anesthesia, heart-lung machine, and surgical methods to see which lead to better recovery and fewer complications. The goal is to gather real-world data to help cre…

This study will test a new device called SaCo VLMA that helps people breathe during laparoscopic surgery under general anesthesia. Researchers will compare it to other airway methods in 20 adults having short elective surgeries. The goal is to see how easy it is to place, how wel…

This study looks at how two different types of anesthesia affect inflammation after inguinal hernia repair. Forty adults having hernia surgery will be randomly assigned to receive either total intravenous anesthesia (TIVA) or inhaled anesthesia. Researchers will measure inflammat…

This study tests a computer program that uses artificial intelligence to predict how patients will respond to anesthesia during surgery. The goal is to help doctors monitor patients more accurately and prevent complications. About 115 adults having planned surgery will take part,…

This study is about translating and testing a questionnaire called QoR-15 for Romanian-speaking patients. The questionnaire measures how well patients recover after surgery and anesthesia. Researchers will ask 250 adults to fill it out to make sure it works correctly in Romanian.…

This study looks at two ways of giving fluids during liver surgery: one that limits fluids and one that gives more. The goal is to see which approach leads to fewer serious problems after surgery, especially kidney injury. About 90 adults having planned liver surgery will take pa…