Which drug keeps the nose Blood-Free during surgery? a Head-to-Head trial

NCT ID NCT07660562

Not yet recruiting Disease control Sponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial compares two medications—remifentanil and nicardipine—given during nasal surgery to lower blood pressure and reduce bleeding. Both are already used in practice, but it is unclear which provides a better surgical view and fewer side effects. The study includes adults undergoing elective nasal surgery and measures surgical field quality, blood loss, and recovery time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: remifentanil and nicardipine
What this could lead to: If one drug works better, it could become the preferred method for controlling bleeding during nasal surgeries, leading to safer procedures and better outcomes.
What could go wrong: This is a small, early-stage trial with only 44 participants, so results may not apply to all patients. Both drugs have known side effects like low blood pressure or slow heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA CONTROLLED HYPOTENSION FOR NASAL SURGERIES NASAL SURGERY

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