New nerve block could replace morphine for C-Section pain

NCT ID NCT07712783

Not yet recruiting Symptom relief Sponsor: Ondokuz Mayıs University Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This trial tests whether a nerve block called a lateral quadratus lumborum block (QLB) can control pain after a C-section as well as the standard treatment, spinal morphine, but with fewer side effects. The study includes women having an elective C-section under spinal anesthesia. Half receive the nerve block and half receive spinal morphine, and their pain and opioid use are compared for 48 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lateral quadratus lumborum block (QLB) with 0.25% bupivacaine
What this could lead to: If effective, this nerve block could offer a non-opioid option for pain relief after C-section, reducing side effects like nausea and itching.
What could go wrong: This is a small, early-stage trial, so results may not apply to all patients. The nerve block may not be as effective as morphine for severe pain.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA POSTOPERATIVE PAIN REGIONAL ANESTHESIA

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Ondokuz Mayis University

Samsun, Turkey (Türkiye)

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