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Small study aims to uncover how surgery affects the aging brain

NCT ID NCT07470216

Not yet recruiting Knowledge-focused Sponsor: University of Edinburgh Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why some older people experience confusion or memory problems after major surgery. Researchers will test 40 patients aged 70 and older before and after colorectal or urological surgery. They will use memory tests and blood samples to see if they can link changes in thinking to details of the anaesthetic. The goal is to see if these research methods work well enough to use in a much larger future study.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could pave the way for larger studies aimed at making surgery safer for the brain in older people.
What could go wrong
This is a very small feasibility study with only 40 participants, so it cannot prove any treatment works. It is designed to test research methods, not to find a cure or treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA ANESTHESIA BRAIN MONITORING ANESTHESIA DEPTH MONITORING COGNITIVE IMPAIRMENT COGNITIVE IMPAIRMENT, MILD COGNITIVE IMPAIRMENT, PROGRESSIVE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Western General Hospital

    Edinburgh, Midlothian, EH4 2XU, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.