Could a drug combo make surgery safer? new trial tests blood pressure control
NCT ID NCT07659496
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial compares two ways to lower blood pressure on purpose during ear, nose, and throat surgery. One uses only remifentanil, a fast-acting opioid; the other adds nicardipine, a drug that widens blood vessels. The goal is to see which approach gives surgeons a clearer view and reduces bleeding, while keeping the heart and organs safe. About 60 adults having routine surgery will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
remifentanil and nicardipine
What this could lead to
If one regimen proves better, it could lead to safer and more effective blood pressure control during surgery, improving outcomes for patients.
What could go wrong
This is a small, single-center study, so results may not apply to all patients. Both drugs have side effects like low blood pressure or slow heart rate.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dicle University
Diyarbakır, Eyalet/Yerleşke, 21070, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••