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Could a safer anesthetic help premature babies born by C-Section?

NCT ID NCT02029898

Completed Knowledge-focused Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether using remifentanil, a fast-acting opioid, during general anesthesia for emergency C-sections affects how well premature babies adapt after birth. Researchers compared two groups of mothers and their premature babies: one group received remifentanil, the other a placebo. The main goal was to check Apgar scores (a measure of newborn health) at 5 minutes after birth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
remifentanil
What this could lead to
If successful, this could help doctors choose safer anesthesia for emergency C-sections in premature births, potentially improving newborn outcomes.
What could go wrong
This is an early-phase, single-center study with only 53 participants, so results may not apply broadly. The primary focus is safety, not a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA CESAREAN SECTION

Contacts and locations

Locations

  • CHU de Rouen

    Rouen, 76031, France

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