Simple betadine wash before C-Section may slash infection risk
NCT ID NCT07715409
First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time
Summary
This trial tests whether cleaning the vagina with a betadine solution for 30 seconds just before a cesarean section can lower the chance of wound infections, fever, and uterine infection after surgery. About 600 women having either planned or emergency C-sections will take part. The study compares those who receive the betadine wash plus standard antibiotics to those who receive antibiotics alone.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- povidone-iodine 5% solution applied vaginally before cesarean section
- What this could lead to
- If effective, this simple, low-cost step could become standard practice to reduce infections after C-sections, benefiting millions of women worldwide.
- What could go wrong
- This is a single-center trial, and results may not apply to all hospitals or populations. The benefit may be small or absent in women already receiving antibiotics.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 600 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2027
An estimate. Start dates often move.
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- Women undergoing elective or emergency cesarean section. Received prophylactic antibiotics before surgery Exclusion Criteria: * Active infection No prophylactic antibiotics Chorioamnionitis Placenta previa with antepartum hemorrhage
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Al-Azhar University Hospital, Damietta
Damietta, Damietta Governorate, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Effectiveness of health educational program for primigravida women in reducing the rate of unnecessary cesarean section
- Can a simple ointment make surgical scars heal better?
- Two common drugs face off to shield mothers from a dangerous drop in blood pressure
- Can simple recovery checklists after cesarean boost patient well-being?
- Can we predict severe pain after C-Section?
- Can a slower oxytocin infusion prevent dangerous blood pressure drops in C-Sections?