C-Section drug showdown: norepinephrine beats phenylephrine for stable blood pressure

NCT ID NCT07327320

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two medications, norepinephrine and phenylephrine, given continuously during C-sections to prevent dangerously low blood pressure. 98 women participated. Norepinephrine was more effective, causing low blood pressure in only 14.9% of cases compared to 42.6% with phenylephrine, and also led to steadier heart rates. Both drugs were safe for the babies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

norepinephrine and phenylephrine

What this could lead to

If confirmed, this could lead to a preferred drug for preventing low blood pressure during C-sections, improving safety and comfort for mothers.

What could go wrong

This is a single, small Phase 4 trial. Results may not apply to all hospitals or patients, and long-term effects were not studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypotensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tam Anh TP. Ho Chi Minh General Hospital

    Ho Chi Minh City, Ho Chi Minh, 700000, Vietnam