POSTOPERATIVE PAIN

This study tests a dental procedure for people with a narrow jawbone who need dental implants. Surgeons will split the bone, place the implant, and cover it with a special membrane made from the patient's own blood to help healing. The study will measure pain, gum thickness, and …

This study compares two types of nerve blocks (SAP and SPSIP) to see which provides better pain relief after breast surgery (mammoplasty). Sixty women aged 18-85 will be randomly assigned to receive one of the blocks. Researchers will measure pain levels, opioid use, and patient …

This study looks at how a new pain medicine called Anrikefon works in people aged 65 and older after laparoscopic abdominal surgery. Thirty participants will receive the injection three times and have their pain levels and blood drug concentrations measured. The goal is to see if…

This study tests a new pain-blocking injection called the External Oblique Intercostal Plane Block for people having major upper abdominal surgery (like stomach, liver, or pancreas surgery). The goal is to see if it reduces the need for strong painkillers (opioids) and improves r…

This study will compare two types of nerve blocks (iPACK and BiFeS) to see which provides better pain relief after total knee replacement surgery. About 100 adults aged 18-75 will be randomly assigned to receive one of the blocks. The goal is to improve pain control, reduce the n…

This study looks at 50 adults having knee replacement surgery to compare different anesthesia techniques—like general or spinal anesthesia with nerve blocks—for controlling pain afterward. Researchers will measure pain levels, painkiller use, side effects, and patient satisfactio…

This study compares two types of nerve blocks (M-TAPA and ESPB) to see which provides better pain relief after laparoscopic gallbladder removal. About 124 adults having elective surgery will receive one of the two blocks, and researchers will measure pain scores, opioid use, and …

This study tests whether a special nerve block (external oblique intercostal block) can reduce pain and the need for strong painkillers after gallbladder removal surgery. About 56 adults having planned laparoscopic gallbladder removal will either get the block or not. The main go…

This study tests an experimental pain medicine called CPL-01 in 112 adults who are having bunion surgery. Half will get the drug, half a placebo. Researchers will measure how much pain people feel and how much extra pain medicine they need after the operation.

This study compares two ways of giving acetaminophen (Tylenol) after lumbar spine fusion surgery: by mouth or through an IV. 180 adults will be randomly assigned to one of the two groups. The goal is to see which method provides better pain relief and helps patients recover faste…

This study tests two methods to control pain after keyhole stomach cancer surgery. One method uses a standard ultrasound-guided nerve block, while the other applies a special temperature-sensitive gel mixed with a numbing medicine directly to the surgical site. The goal is to see…

This study tests whether a magnesium drip given after a C-section can lower pain and help new mothers recover faster. About 150 women having planned or non-urgent C-sections will receive either magnesium or a saltwater placebo, and neither they nor their doctors will know which. …

This study looks at whether using a special pillow placed behind the shoulder can help reduce pain and improve sleep quality for people recovering from rotator cuff repair surgery. About 126 adults aged 40 to 70 will take part. Researchers will compare those who use the pillow wi…

This study looks at two ways to manage pain after hip replacement surgery. One group gets a standard nerve block, and the other gets that plus an extra block targeting the back of the hip. The goal is to see if the extra block provides better pain relief. About 40 adults having h…

This study tests whether a special nerve block (ESP block) can reduce pain and the need for strong painkillers after spinal fusion surgery. About 75 adults having back or neck fusion will be randomly assigned to receive either a standard numbing medicine or a longer-acting versio…

This study tests a new type of nerve block (SPSIPB) to see if it can better control pain after heart surgery. 120 adults having elective heart surgery will either get the nerve block plus standard painkillers or standard care alone. The goal is to reduce the amount of strong pain…

This study tests whether rinsing with hydrogen water can reduce pain, mouth sores, and inflammation in 36 adults recovering from oral cancer surgery with free flap reconstruction. Participants will use hydrogen water mouth care for 7 days after surgery, and researchers will measu…

This study compares two ultrasound-guided pain-blocking techniques for adults having open-heart surgery. The goal is to see which method better reduces the need for strong painkillers (opioids) in the first 24 hours after surgery. 80 participants will be randomly assigned to rece…

This study looks at whether two types of breathing exercises—pranayama and pursed-lip breathing—can help reduce pain and anxiety after breast surgery. About 126 adults having their first mastectomy will be split into three groups: one doing pranayama, one doing pursed-lip breathi…

This study tests whether adding a special nerve block (M-TAPA) to standard pain relief can reduce pain and the need for strong opioids after open-heart surgery. About 80 adults having elective open-heart surgery will receive either the block plus standard care or standard care al…

This study compares two ultrasound-guided nerve blocks (transversalis fascia plane block and erector spinae plane block) for pain relief after cesarean section. Researchers will enroll 60 women aged 18-50 to see which block better reduces pain and the need for opioid painkillers.…

This study tests if using a cold anti-inflammatory liquid (ketorolac) inside the tooth after root canal can lower pain better than the same liquid at room temperature. Sixty adults with infected teeth will be treated and asked to rate their pain. The goal is to find a simple way …

This study compares three ways to manage pain after gallbladder removal surgery: two types of nerve blocks and standard pain medication. The goal is to see which method reduces the need for strong painkillers (opioids) and improves recovery. About 147 adults having planned gallbl…

This study looks at whether a device called TENS, which uses mild electrical pulses, can help reduce pain and improve sleep in adults after inguinal hernia surgery. About 80 participants will either receive TENS or standard care after their operation. Researchers will measure pai…

This study tests a non-invasive device that gently stimulates a nerve in the ear to see if it can reduce pain and the need for strong painkillers after complex spine surgery. About 98 adults having spinal surgery will be randomly assigned to receive either the real stimulation or…

This study looks at whether adding a steroid (dexamethasone) to a standard pain medicine (dexmedetomidine) can improve pain control after shoulder surgery. About 70 adults having shoulder arthroscopy will get a nerve block and either the steroid or a placebo. The goal is to see h…

This study compares two ways to manage pain after lung surgery: a nerve block (injection near the ribs) and spinal morphine. Sixty adults having lung surgery will be randomly assigned to one method. The goal is to see which approach reduces the need for opioids and improves recov…

This study compares two common nerve block techniques used to reduce pain and nausea after laparoscopic gallbladder removal. About 76 adults having elective surgery will receive one of the two blocks while under anesthesia. The goal is to see which method leads to a better qualit…

This study tests two different nerve blocks to see which one works better for pain after breast cancer surgery that also removes lymph nodes from the armpit. About 50 women will take part, and researchers will measure their pain levels, how much extra pain medicine they need, and…

This study compares two types of nerve blocks (SPSIP and ESP) to see which one works better for pain after surgery to fix broken ribs. About 50 adults will take part, and researchers will measure pain levels, how much pain medicine is needed, and any side effects. The goal is to …

This study compares two types of nerve blocks (QIPB and SIFICB) to see which one works better for pain after hip surgery. Sixty adults having hip surgery will be randomly assigned to receive one of the two blocks. The main goal is to measure pain levels using a 0-10 scale and tra…

This study compares two types of nerve blocks to see which one better controls pain after open ventral hernia repair. Fifty adults will receive either an erector spinae plane block or an external oblique-intercostal plane block before surgery. The main goal is to measure how much…

This study compares two types of nerve blocks to control pain after video-assisted lung surgery. Sixty adults will receive one of the two blocks, and researchers will measure pain levels, opioid use, and side effects over 24 hours. The goal is to find which block provides better …

This study will observe 250 children aged 2 to 8 who are having urogenital surgery. Researchers want to see if the length of time they fast before surgery affects their pain and agitation after the procedure. The goal is to find the best fasting time to improve recovery.