Which pain block works best for sleeve gastrectomy?
NCT ID NCT07654556
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will compare two types of nerve blocks (M-TAPA and ESP block) to see which provides better pain relief after laparoscopic sleeve gastrectomy. Sixty-four patients will receive an injection of the numbing medicine bupivacaine in one of the two block techniques. Pain scores will be measured for 48 hours after surgery to determine which approach is more effective.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If one block proves better, it could improve pain control and reduce opioid use after weight-loss surgery.
- What could go wrong
- This is a small, early-stage study with only 64 participants, so results may not apply to all patients. Both blocks are already used, so no major breakthrough is expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 64 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients from both sexes. * 18 to 60 years old. * ASA physical status II-III scheduled for laparoscopic sleeve gastrectomy. * Patients with BMI (40-50) kg/ m2 Exclusion Criteria: * Patient Refusal * Lack of patient cooperation. * Patients with any contraindication to regional nerve blocks as coagulopathy or infection at site of injection * Patients with anatomical abnormalities at site of injection * Patients with known hypersensitivity to bupivacaine, or any of the used drugs. * Patients with pre-existing neurological disorder * Patients with chronic pain syndromes including fibromyalgia, complex regional pain syndrome (CRPS), or chronic pain requiring long-term opioid or neuropathic pain medications. * Patients with history of long-acting opioids, steroids, anticonvulsants perioperatively.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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