New wound gel could replace opioids after hand surgery
NCT ID NCT07644923
First seen Jun 19, 2026 · Last updated Jun 19, 2026
Summary
This study tests whether applying a mix of numbing drugs and clotting agents directly to surgical wounds can reduce pain and the need for opioid pills after hand surgery. Forty adults having elective hand surgery will be randomly assigned to one of four combinations of these drugs. The goal is to find a safer, non-addictive way to manage post-surgery pain.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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NYU Langone Health
New York, New York, 10016, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
a mixture of local anesthetics (bupivacaine, lidocaine) and clotting drugs (thrombin, tranexamic acid, aminocaproic acid) applied to the surgical wound
What this could lead to
If it works, this could offer a way to manage pain after hand surgery without relying on opioid pills.
What could go wrong
This is a small, early-phase trial with only 40 participants, so results may not apply to everyone. The drug mixture is experimental and may not provide better pain relief than standard care.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.