POSTOPERATIVE PAIN

This study compares two methods to manage pain after hip surgery: a fascia iliaca block (an injection near the hip nerves) and intrathecal nalbuphine (a painkiller given with spinal anesthesia). The goal is to see which approach keeps patients comfortable longer after surgery. Th…

This study compares two types of nerve blocks—sacral erector spinae plane block and pericapsular nerve group block—for pain relief after hip replacement surgery in 80 adults aged 50 to 90. The goal is to see which block provides better pain control while preserving leg muscle str…

This study tests whether asking patients to keep a pain diary after gallbladder surgery helps them report pain more accurately than standard methods. About 142 adults having their first laparoscopic gallbladder removal will either use a diary or receive usual care. The goal is to…

This study tests two different ultrasound-guided nerve blocks to see which one works better for pain after mastectomy. About 66 women having mastectomy will get one of the two blocks before surgery. The goal is to find a method that reduces pain, delays the need for painkillers, …

This study compares two types of nerve blocks (DIPB and SIFIB) to see which provides better pain relief after hip replacement surgery. 70 adults having hip surgery will receive one of the two blocks, and researchers will measure their pain, need for extra pain medicine, and leg w…

This study tests two types of nerve blocks to see which one works better for pain after breast cancer surgery. About 50 women having a mastectomy will get either a newer or a standard block. The goal is to find a way to reduce the need for strong painkillers like morphine and hel…

This study compares 4mg and 8mg of dexamethasone (a steroid) given at the surgical site to reduce pain after dental implant surgery. 138 adults will be randomly assigned to receive one of the two doses or a placebo. Pain will be measured for 6 days after surgery, and the number o…

This study tests whether adding an ultrasound-guided nerve block to standard pain medicine can reduce the need for strong painkillers after lower back surgery. About 50 adults having elective lumbar spine surgery will be randomly assigned to receive either the nerve block plus us…

This study looks at whether a new type of nerve block, called Quadro-Iliac plane block, can help control pain after lower back surgery. The block is done using ultrasound to guide the injection. Researchers will measure how much pain medicine patients need and how well they recov…

This study looks at whether using lidocaine as a spray inside the belly plus through an IV can lower moderate-to-severe pain after keyhole surgery to remove uterine fibroids. About 100 adults aged 18-65 having this surgery will take part. The main goal is to see how many people h…

This study tests whether a special nerve block called the Quadro-Iliac plane block can improve recovery after laparoscopic inguinal hernia surgery. About 70 adults having elective surgery will be randomly assigned to receive either the nerve block or a placebo, and their recovery…

This study tests if a numbing injection (TAP block) given during laparoscopic hernia repair can lower pain after surgery and help patients recover faster. About 100 adults having planned hernia surgery will be randomly assigned to get the injection or not. Researchers will measur…

This study tests three different agents (sodium hypochlorite, chlorhexidine, and cold saline) to stop bleeding during a partial pulpotomy, a dental procedure that removes only the top part of the tooth's pulp. Researchers will measure pain levels and how well the pulp survives ov…

This study is testing whether a low dose of ketamine can help reduce the amount of strong painkillers (opioids) needed and lower pain levels in people recovering from a type of aortic repair surgery called TEVAR. About 30 adults scheduled for this surgery will receive either keta…

This study tests if a numbing injection near the breastbone, given before heart surgery, can lower the amount of strong pain medicine (opioids) needed during the operation. About 80 adults having planned heart surgery will be randomly assigned to get either the injection plus sta…

This study is testing a painkiller called EXPAREL in children under 6 years old who are having heart surgery. The goal is to see how the drug moves through the body and if it is safe compared to a standard painkiller. About 48 children will take part, and the medicine is given as…

This study tests whether a nose spray containing two medicines (dexmedetomidine and esketamine) can reduce pain in children aged 3-7 after tonsil and adenoid surgery. About 160 children will receive either the spray or a placebo, and their pain will be tracked for 48 hours. The g…

This study tests whether giving oxytocin through an IV during surgery can lower pain and the need for opioid painkillers after a minimally invasive hysterectomy. About 152 adults having this surgery will be randomly assigned to receive either oxytocin or a placebo. The goal is to…

This study looks at whether giving a nerve block before or after gallbladder surgery helps with pain. 96 adults having laparoscopic gallbladder removal will be randomly assigned to get the block either before the surgeon starts or after the surgery ends. The goal is to find the b…

This study tests whether adding a low dose of morphine to the standard spinal anesthesia can reduce pain after a planned C-section without increasing serious risks for mothers or babies. About 1,300 women having planned C-sections will receive either morphine or a placebo (salt w…

This study looks at whether a simple, non-invasive device called TENS can help people recover from gallbladder removal surgery. TENS uses mild electrical pulses through the skin to calm nerves. Researchers want to see if it reduces anxiety before surgery, lessens pain afterward, …

This study is testing whether a 15-20 minute hypnosis session right before abdominal surgery can lower patients' anxiety and pain. About 48 adults having abdominal surgery will be randomly assigned to receive either hypnosis or standard psychological preparation. The main goal is…

This study compares two types of nerve blocks (paravertebral block and erector spinae plane block) to see which one better controls pain and reduces opioid use during thoracotomy (chest surgery). About 60 adults having elective chest surgery will take part. The goal is to find a …

This study compares two ways to manage pain after a gum graft procedure: a new oral wound dressing called Ora-Aid versus a standard plastic stent. Twenty adults having gum graft surgery will be randomly assigned to one of the two treatments. The main goal is to see which method r…

This study tests whether combining two ultrasound-guided pain-block techniques (M-TAPA and EXOP) works better than M-TAPA alone for controlling pain after laparoscopic gynecologic surgery. About 86 adults having this surgery will be enrolled. Researchers will measure pain scores,…

This study tests whether a numbing injection (paracervical block) given during prolapse surgery can lower pain right after the procedure. About 58 women having surgery for pelvic organ prolapse will be randomly assigned to get either the numbing medicine or a placebo. Researchers…

This study tests two different techniques to reduce bleeding and pain during lower back fusion surgery. One method injects a numbing and blood vessel-constricting medicine around the spine, while the other uses a targeted nerve block. The goal is to see which approach works bette…

This study tests whether injecting the painkiller bupivacaine into surgical sites can reduce pain after laparoscopic hysterectomy (removal of the uterus through small cuts). About 120 women having this surgery for non-cancer reasons will be randomly assigned to receive the inject…

This study tests whether a rectus sheath block—a type of nerve block—can reduce pain and the need for strong painkillers after heart surgery. About 75 adults having heart surgery with chest tubes will be randomly assigned to receive the block or not. Researchers will measure pain…

This study compares two types of nerve blocks to control pain after heart surgery through the breastbone. Fifty adults having planned heart surgery will receive either a combination of two blocks or a single block, along with standard pain medicines. The goal is to see which meth…

This study tests whether giving ketamine before laparoscopic sleeve gastrectomy (a type of weight-loss surgery) can reduce pain after the operation. Researchers will compare how long it takes for patients to need extra pain medicine. The study includes 90 adults with a BMI betwee…

This study compares tea tree oil mouthwash to the standard chlorhexidine mouthwash for people recovering from impacted wisdom tooth removal. About 54 adults will use one of the two mouthwashes for 7 days after surgery. Researchers will measure pain, swelling, and gum healing to s…

This study tests whether a newer nerve block (EXORA) works as well as or better than a standard one (ESP) for controlling pain after laparoscopic gallbladder removal. About 114 adults having elective surgery will receive one of the two blocks. The goal is to reduce pain and the n…

This study watches 254 adults after elective surgery to see what factors affect how much pain medicine they need in the recovery room. No new treatments are given—just routine care. The goal is to find patterns that help doctors personalize pain management and improve recovery.

This study tests a non-invasive device that measures pain in children and teens by tracking pupil changes after gentle electrical stimulation. It includes 100 participants aged 6 to 21 who are having surgery or bone marrow transplant. The device does not guide treatment—it only c…

This study aims to understand why some people feel more pain after surgery than others. Researchers will analyze genetic and non-genetic factors in 5,000 adults undergoing elective surgery. The goal is to improve pain management by identifying factors that influence pain and reco…

This study looks at whether parents who feel more confident in supporting their child's independence can help reduce their child's pain after minor surgery. About 150 children aged 3 to 18 and their parents will take part at one hospital in Turkey. Parents will fill out questionn…

This study looks at whether a person's genes affect how well the painkiller nalbuphine works after abdominal surgery. Researchers will take blood samples from 263 adults before and after surgery to find genetic links to pain relief and side effects. The goal is to make pain manag…

This study looks at whether the quality of sleep before breast cancer surgery affects pain and inflammation after the operation. Researchers will track 150 women, measuring their sleep quality, blood markers of inflammation, and pain levels. The goal is to see if poor sleepers ha…

This study looks at how patients experience pain monitoring after planned general surgery. Researchers want to know if patients find these checks helpful or stressful, and how that affects their trust in nurses and willingness to report pain. About 300 adults will fill out survey…