New pain block could cut opioid use after gallbladder surgery
NCT ID NCT07187310
First seen Jun 27, 2026 · Last updated Sep 03, 2026 · Updated 2 times
Summary
This study tests two types of nerve blocks (EXORA and ESP) to see which one works better for pain after gallbladder removal. About 114 adults having laparoscopic gallbladder surgery will receive one of the blocks before surgery. The goal is to find which block reduces the need for strong painkillers (opioids) and helps patients recover faster with fewer side effects.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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114 people
The number who actually took part.
- Started
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Dec 2025
- Finished
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Aug 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Elective laparoscopic cholecystectomy * ASA physical status I-III Exclusion Criteria: * Known allergy to local anesthetics * Chronic pain or regular opioid use * Coagulopathy or anticoagulant therapy * Local infection at the block site * BMI more than 35 kg/m2 * Neurological or psychiatric disorders * Refusal to participate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fayoum University hospital
El Fayoum Qesm, Faiyum Governorate, 63514, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a common anesthetic stop Post-Surgery delirium in the elderly?
- Can a single drug dose curb opioid side effects after kidney stone surgery?
- Can a new Non-Opioid pill cut painkiller needs after throat surgery?
- Can zapping three acupoints rewire the brain to ease surgical pain?
- Can a triage checklist ease pain months after emergency surgery?
- Can a nerve block quiet the brain during gallbladder surgery?