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New painkiller may offer longer relief after gallbladder surgery

NCT ID NCT07577934

Symptom relief Sponsor: Tianjin First Central Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a long-acting painkiller (liposomal bupivacaine) works better than a standard one (ropivacaine) for pain after gallbladder removal. About 86 adults having laparoscopic cholecystectomy will receive one of the two drugs via a nerve block during surgery. Researchers will measure pain levels, recovery quality, and side effects over three months to see which option provides better pain control and faster recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
liposomal bupivacaine
What this could lead to
If liposomal bupivacaine works better, it could provide longer-lasting pain relief after gallbladder surgery, helping patients recover faster and possibly reducing the risk of long-term pain.
What could go wrong
This is a small, early-stage trial with only 86 people. The results may not apply to everyone, and there is no guarantee that liposomal bupivacaine will be more effective than the standard drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 86 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-65 years, either gender. * Patients scheduled for elective laparoscopic cholecystectomy. * ASA physical status I-III. * Able to provide written informed consent and complete the 3-month follow-up. Exclusion Criteria: * History of allergy to local anesthetics. * History of dementia, psychosis, or other central nervous system diseases. * History of chronic pain or long-term use of opioids or other analgesics. * Contraindications to nerve block: infection at puncture site, severe coagulopathy. * Severe hepatic or renal dysfunction, pregnancy, or lactation.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Liposomal bupivacaine Postoperative pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Tianjin First Central Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300384, China

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