Could a simple painkiller wash replace opioids after gallbladder surgery?
NCT ID NCT07650760
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares using bupivacaine (a numbing medicine) versus salt water (placebo) to wash the inside of the abdomen after laparoscopic gallbladder removal. The goal is to see if bupivacaine provides better pain relief. 106 adults aged 18–60 having elective surgery are being enrolled.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If it works, this could offer a simple, non-opioid way to manage pain after gallbladder surgery.
- What could go wrong
- This is a small, single-center trial. Previous studies suggest benefit, but results may not apply to all patients or surgeries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 106 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Adult consented patients of any gender aged 18 to 60 years Fit to undergo elective laparoscopic cholecystectomy Exclusion Criteria: * • Patients who had developed choledocholithiasis or pancreatitis pre-operatively * Where conversion to open cholecystectomy is needed intraoperatively * Pregnant or lactating * Inability to express pain appropriately, like in psychiatric disorders * With any contraindication to the use of bupivacaine or normal saline, e.g., hypersensitivity
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Wah Medical College, POF Hospital Wah cantt Wāh
RECRUITINGWāh, Punjab Province, 47040, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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