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New nerve block could cut opioid use for kidney donors

NCT ID NCT07396753

First seen Feb 22, 2026 · Last updated Jun 23, 2026 · Updated 22 times

Summary

This study tests whether a nerve block called the transversalis fascia plane block can reduce pain and opioid use after hand-assisted laparoscopic donor nephrectomy. Fifty living kidney donors will be randomly assigned to receive either standard anesthesia alone or standard anesthesia plus the nerve block. The main goal is to see if the block lowers opioid consumption in the first 24 hours after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Koç University Hospital

    RECRUITING

    Istanbul, Zeytinburnu, 34010, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bupivacaine

What this could lead to

If it works, this could provide a better way to manage pain after kidney donation, reducing the need for opioids and their side effects.

What could go wrong

This is a small, early-stage study with only 50 participants. The nerve block may not significantly reduce pain or opioid use, and results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

agnosia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.