New nerve block could cut opioid use for kidney donors

NCT ID NCT07396753

Recruiting now Symptom relief Sponsor: Koç University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a nerve block called the transversalis fascia plane block can reduce pain and opioid use after hand-assisted laparoscopic donor nephrectomy. Fifty living kidney donors will be randomly assigned to receive either standard anesthesia alone or standard anesthesia plus the nerve block. The main goal is to see if the block lowers opioid consumption in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bupivacaine
What this could lead to: If it works, this could provide a better way to manage pain after kidney donation, reducing the need for opioids and their side effects.
What could go wrong: This is a small, early-stage study with only 50 participants. The nerve block may not significantly reduce pain or opioid use, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agnosia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANALGESICS, OPIOID ANESTHESIA, REGIONAL LIVING DONORS NEPHRECTOMY,KIDNEY DONATION PAIN MANAGEMENT POSTOPERATIVE PAIN

Contacts and locations

Locations

Koç University Hospital
RECRUITING

Istanbul, Zeytinburnu, 34010, Turkey (Türkiye)

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