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Which opioid is kinder to your gut after gallbladder surgery?

NCT ID NCT07182097

Knowledge-focused Sponsor: Konya City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study compares two common opioid pain medicines, fentanyl and remifentanil, given during laparoscopic gallbladder removal. The goal is to see which one allows the bowels to start working again sooner after surgery. About 106 adults having elective gallbladder surgery will be randomly assigned to receive one of the two drugs, and researchers will measure when they first pass gas, have a bowel movement, and how much pain they feel.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
fentanyl and remifentanil
What this could lead to
If this trial shows one opioid is better, it could guide anesthesiologists to choose the drug that helps patients recover bowel function faster after gallbladder surgery.
What could go wrong
This is a small, early-stage study (106 patients) comparing two common drugs, so the results may not apply to all surgeries or patients. The difference between the two drugs may be small or not clinically meaningful.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 106 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-65 years * American Society of Anesthesiologists (ASA) physical status I or II * Scheduled for elective laparoscopic cholecystectomy * Provided written informed consent Exclusion Criteria: * Opioid use preoperatively * Previous abdominal surgery * History of ileus or gastrointestinal disease * Preoperative electrolyte imbalance * Liver or renal failure * Neuromuscular or psychiatric disorders * Known allergy to study medications * Emergency surgery * Surgical duration exceeding 90 minutes

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative bowel function Postoperative pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Konya City Hospital

    RECRUITING

    Karatay, Konya, 42050, Turkey (Türkiye)

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