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Nerve block combo may ease pain after breast surgery

NCT ID NCT07401602

Symptom relief Sponsor: Istinye University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at three ways to manage pain after mastectomy: standard pain medication, a nerve block called rhomboid intercostal block (RIB), or a combination of RIB with another nerve block. Researchers will review medical records of 66 women to see which method provides the best pain relief in the first 24 hours. The goal is to find a more effective way to control pain and reduce the need for opioids.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nerve block (rhomboid intercostal block and deep parasternal intercostal plane block)
What this could lead to
If successful, this could show that a specific nerve block combination provides better pain relief after mastectomy, potentially reducing the need for strong painkillers.
What could go wrong
This is a small, retrospective study (66 people) that only looks back at medical records, so it cannot prove cause and effect. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 66 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult female patients aged 18-70 years who underwent elective mastectomy at a single tertiary care center between October 2024 and October 2025 and had complete postoperative pain and analgesia records available for retrospective analysis.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female patients aged 18-70 years * Elective mastectomy performed between October 2024 and October 2025 * ASA physical status I-III * Complete postoperative pain and analgesia records for the first 24 hours * Clearly documented analgesic technique (systemic analgesia, RIB, or RIB + DPIPB) Exclusion Criteria: * Incomplete or missing medical records * Emergency mastectomy or emergency surgery * Reoperation within the first 24 hours postoperatively * Major intraoperative complications preventing standard analgesia * Neurological or psychiatric conditions interfering with pain assessment

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Istinye Üniversity

    Istanbul, Merkez Mahallesi, 34250, Turkey (Türkiye)

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