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Could hydrogen water soothe mouth pain after cancer surgery?

NCT ID NCT07306546

First seen Jan 04, 2026 · Last updated Jun 23, 2026 · Updated 30 times

Summary

This study tests whether rinsing with hydrogen water can reduce inflammation, mouth sores, and pain in people recovering from oral cancer surgery with free flap reconstruction. Thirty-six participants will use either hydrogen water or regular water for oral care over 7 days. Researchers will measure changes in saliva markers of inflammation and oral health scores.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hydrogen water

What this could lead to

If it works, this could offer a simple, low-cost way to ease pain and speed healing after oral cancer surgery.

What could go wrong

This is a very small early trial with only 36 people, so results may not apply widely. Hydrogen water is generally safe, but its effectiveness for this use is unproven.

Conditions

The condition(s) this trial relates to.

lip and oral cavity carcinoma Mouth Neoplasms oral cavity squamous cell carcinoma Pain, Postoperative Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.