Could hydrogen water soothe mouth pain after oral cancer surgery?

NCT ID NCT07306546

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether rinsing with hydrogen water can reduce mouth inflammation and pain in people recovering from oral cancer surgery that used a free flap reconstruction. Thirty-six participants will use hydrogen water or plain water for oral care over 7 days. Researchers will measure changes in saliva markers of inflammation and mouth soreness scores.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
hydrogen water
What this could lead to
If it works, this could point toward a simple, low-cost way to ease mouth inflammation and pain after oral cancer surgery.
What could go wrong
This is a very small, early-stage trial with only 36 participants. The effect may be small or not noticeable, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for FREE FLAP RECONSTRUCTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

lip and oral cavity carcinoma Mouth Neoplasms oral cavity squamous cell carcinoma Pain, Postoperative Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.