New study aims to cut opioid use after spinal fusion
NCT ID NCT07228039
First seen Nov 15, 2025 · Last updated Jun 21, 2026 · Updated 28 times
Summary
This study tests whether a specific type of nerve block (ESP block) can reduce pain and the need for strong painkillers after spinal fusion surgery. 75 adults will be randomly assigned to receive either a standard painkiller (bupivacaine) or a longer-acting version mixed with liposomal bupivacaine. Researchers will measure pain scores, opioid use, and how quickly patients can get out of bed and go home.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for POSTOPERATIVE PAIN are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
-
Duke University
Durham, North Carolina, 27710, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine with or without liposomal bupivacaine
What this could lead to
If it works, this could point toward a better way to manage pain after spinal surgery, reducing the need for strong painkillers.
What could go wrong
This is a small, early-phase study (75 people) testing a well-known painkiller in a new way. It may not show a meaningful difference between the two approaches.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.