Tylenol showdown: pill or IV after back surgery?
NCT ID NCT07203079
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 30 times
Summary
This study will test whether taking acetaminophen (Tylenol) by mouth works as well as getting it through an IV for pain after lumbar spine fusion surgery. About 180 adults will be randomly assigned to receive either oral or IV acetaminophen for 48 hours after their operation. The goal is to see if the simpler oral route can provide similar pain relief and help people recover faster.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Stanford University
Stanford, California, 94305, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
acetaminophen (Tylenol)
What this could lead to
If oral acetaminophen works as well as IV, patients could avoid an IV line for pain relief after spine surgery, simplifying recovery.
What could go wrong
This is a small, early-phase trial (180 people) comparing two forms of a common drug. The results may not apply to other surgeries or pain types.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.