One shot before wisdom tooth pull may cut pain and lockjaw
NCT ID NCT07554963
First seen May 05, 2026 · Last updated Jun 23, 2026 · Updated 9 times
Summary
This study tests whether a single 4 mg dose of dexamethasone, given as a shot under the gum before surgery, can reduce pain and difficulty opening the mouth after impacted lower wisdom tooth removal. 268 adults aged 18 to 55 will be randomly assigned to receive the steroid or standard care alone. Pain and mouth opening will be measured on days 2 and 7 after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexamethasone
What this could lead to
If it works, this could provide a simple, low-cost way to reduce pain and jaw stiffness after wisdom tooth removal.
What could go wrong
This is a small, early-phase trial. The benefit may be small or not apply to everyone. Dexamethasone can have side effects like delayed healing or infection risk.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.