One shot before wisdom tooth pull may cut pain and lockjaw
NCT ID NCT07554963
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a single 4 mg dose of dexamethasone, given as a shot under the gum before surgery, can reduce pain and difficulty opening the mouth after impacted lower wisdom tooth removal. 268 adults aged 18 to 55 will be randomly assigned to receive the steroid or standard care alone. Pain and mouth opening will be measured on days 2 and 7 after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dexamethasone
- What this could lead to
- If it works, this could provide a simple, low-cost way to reduce pain and jaw stiffness after wisdom tooth removal.
- What could go wrong
- This is a small, early-phase trial. The benefit may be small or not apply to everyone. Dexamethasone can have side effects like delayed healing or infection risk.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for IMPACTED MANDIBULAR THIRD MOLAR are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can patients safely dispense their own pain medicine after surgery?
- Can a VR headset calm nerves before surgery?
- Can a less invasive nerve block match the gold standard for chest surgery pain?
- Could a Pre-Surgery nerve block speed up recovery after hip fracture?
- One injection or many? a test to ease breast surgery pain
- One injection vs. two: a new approach to shoulder surgery pain?