Opioid-Free anesthesia for kidney stone surgery shows promise in new trial
NCT ID NCT07636070
First seen Jun 13, 2026 · Last updated Jun 22, 2026 · Updated 2 times
Summary
This study tests whether a combination of two drugs, dexmedetomidine and ketamine, can replace opioids for pain control during kidney stone surgery. Sixty adults undergoing the procedure will receive either the opioid-free combo or standard fentanyl-based anesthesia. Researchers will measure pain levels and how much extra pain medication is needed after surgery, aiming to find a safer alternative to opioids.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mus State Hospital
Muş, Muş, 49100, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexmedetomidine and ketamine combination
What this could lead to
If successful, this could offer a safer, opioid-free pain management option for kidney stone surgery, reducing reliance on opioids and their side effects.
What could go wrong
This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. The new approach might not control pain as well as standard opioids.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.