ALZHEIMER DISEASE

This early-stage study tested an experimental vaccine called AV-1959R in 16 healthy adults aged 40 to 60. The goal was to see if the vaccine is safe and can trigger an immune response against a protein linked to Alzheimer's disease. Participants received three shots over 14 weeks…

This early-phase study tested a new drug called NH280105 in 32 healthy adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo, and researchers monitored for side effects and changes in lab results. This is a first step toward…

This study tested a fixed-dose combination pill (polypill) in 121 adults aged 50-85 with mild to severe Alzheimer's disease. Over 180 days of treatment, researchers measured changes in memory, thinking, daily function, and overall dementia severity compared to a placebo. The goal…

This study tested a device that uses focused ultrasound to temporarily open the blood-brain barrier in 35 people with Alzheimer's disease. The goal was to see if this procedure is safe and could help treatments reach the brain more effectively. Participants were aged 50-85 and ha…

This study tested different doses of nicotinamide riboside (a form of vitamin B3) in 80 people with early Alzheimer's disease. The goal was to find the dose that best boosts brain energy levels without causing side effects. Participants took pills daily for 12 weeks and had brain…

This study tested whether the antiviral drug valacyclovir (Valtrex) can slow memory and thinking decline in people with mild Alzheimer's disease who also carry the herpes simplex virus. About 120 participants received either the drug or a placebo for 18 months. The goal was to se…

This early-stage study tested a gene therapy called LX1001 in 15 people with a specific genetic form of Alzheimer's (APOE4 homozygotes). The main goal was to check safety and side effects over 52 weeks. Participants had mild cognitive impairment or mild to moderate dementia due t…

This early-phase study tested whether choline, a dietary supplement, is safe and can improve fat metabolism in people with a genetic risk for Alzheimer's disease (APOE4 carriers). Fifteen participants took choline to see if it changes certain fats in their spinal fluid. The goal …

This study tested a drug called donanemab (LY3002813) in 272 people with early Alzheimer's disease. The goal was to see if it is safe and can slow down memory and thinking problems. Participants received either the drug or a placebo, and researchers measured changes in their cogn…

This study tested the drug baricitinib, currently used for arthritis, in 17 people with Alzheimer's disease, ALS, or early memory problems. The goal was to see if the drug could reach the brain and reduce inflammation linked to these diseases. Participants took the drug for 24 we…

This study tested an experimental drug called XPro1595 in 208 people with early Alzheimer's who also had signs of brain inflammation. The goal was to see if the drug could improve thinking, memory, and daily function compared to a placebo. Researchers also checked for safety and …

This small pilot study tested whether a short course of low-dose radiation to the brain can reduce amyloid plaques, a hallmark of Alzheimer's disease. Twenty people with early Alzheimer's and positive amyloid scans participated. The main goals were to check safety and see if radi…

This study tested a drug called TRx0237 in 598 people with Alzheimer's disease. Participants received either a low or high dose of the drug or a placebo for 12 months, followed by another 12 months where everyone could get the drug. The goal was to see if the drug could slow down…

This study tested a one-year virtual program for people with dementia and their caregivers. Care coordinators provided monthly video or phone visits to address symptoms, caregiver stress, medications, and care planning. The goal was to reduce emergency room visits and improve qua…

This study tested a special high-fat, low-carb diet called the ketogenic diet (named JT821) in 32 people with mild to moderate Alzheimer's disease. The goal was to see if the diet could improve memory and thinking skills over 26 weeks compared to a placebo. The diet is thought to…

This study tested an experimental drug called AL002 in 356 people with early Alzheimer's disease. The goal was to see if it could slow down memory and thinking problems compared to a placebo. Participants received either the drug or a dummy treatment for 96 weeks, and researchers…

This study tested whether a nasal insulin spray combined with the diabetes drug empagliflozin can safely improve memory and thinking in people with early Alzheimer's or mild cognitive impairment. 47 adults aged 55-85 with signs of Alzheimer's in their brain took part. The goal wa…

This study tested a vaccine called ABvac40 in 134 people with very mild Alzheimer's or mild cognitive impairment. The vaccine aims to train the immune system to attack a specific protein (Aβ40) linked to Alzheimer's. The main goal was to check safety and immune response over 24 m…

This pilot study tested daratumumab, a cancer drug, in 16 people with mild to moderate Alzheimer's disease. The goal was to see if it could improve thinking and memory. The study was small and open-label, meaning everyone knew they were getting the drug, so results are very early…

This study tested a tool called eRADAR that uses information already in a patient's electronic health records to identify people who might have undiagnosed dementia. Over 1,200 adults without a prior dementia diagnosis took part. The goal was to see if this low-cost method could …

This study looked at whether measuring a substance called amyloid beta 1-40 in spinal fluid can help doctors diagnose Alzheimer's disease more reliably. Current tests sometimes give unclear results. The researchers tested 204 people with memory problems to see if adding this new …

This study tested whether a finger prick blood sample can accurately measure Alzheimer's disease biomarkers, specifically pTau-217, compared to standard blood draws from a vein. Researchers enrolled 49 adults already participating in an Alzheimer's study. The goal was to see if t…

This completed study looked at whether a quick online memory test followed by a blood test can help detect Alzheimer's disease earlier in people aged 65 and older. Over 1,400 volunteers took part. The goal is to make diagnosis faster and easier, so treatment can start sooner and …

This study tested whether an artificial intelligence system could detect mild cognitive impairment and Alzheimer's disease by analyzing people's self-figure drawings. Over 3,400 older adults participated, drawing themselves on paper. The goal was to create a simple, non-invasive …

This study tested a smartphone app that analyzes voice recordings to see if it can accurately diagnose mild cognitive impairment (MCI) and Alzheimer's disease. Researchers compared the app's diagnosis to a doctor's clinical diagnosis in 150 adults aged 50 and older. The goal was …

This study tested a new blood test to see if it can help diagnose Alzheimer's disease. Researchers measured two specific markers in the blood of 200 people, including those with Alzheimer's and healthy volunteers, over 24 months. The goal was to see if these markers can reliably …

This study looked at whether a blood test can accurately diagnose Alzheimer's disease, instead of the usual spinal fluid test. Researchers tested 342 adults visiting memory clinics. They measured certain proteins in the blood and compared results to standard diagnostic methods. T…

This study tested whether a combination of physical exercise, mental challenges, a healthy diet, and social activities can protect memory and thinking in older adults at risk for Alzheimer's. Researchers enrolled 2,000 sedentary Americans with low diet scores but no current memor…

This study tested whether a lifestyle program—including diet, exercise, and brain training—could reduce the risk of dementia in older adults aged 60 to 77 across 12 Latin American countries. Over 1,000 participants at risk for Alzheimer's took part. The goal was to see if such a …

This study tested a 4-week program called Zinde Zihin ("Fit Mind") in 62 older adults living in nursing homes. The program included brain games, exercise, nutrition advice, and stress management. Researchers measured changes in Alzheimer's risk scores and found that the program m…

This study tested a combination of transcranial magnetic stimulation (TMS) — a non-invasive brain stimulation technique — and a specific language therapy in 23 people with mild-to-moderate Alzheimer's disease. The goal was to see if this approach could improve their ability to sp…

This study tested a program called MEMORI Corps, where trained volunteers aged 55+ spend time with people who have dementia, doing fun and meaningful activities together. The goal was to see if this companionship could reduce loneliness and improve quality of life for people with…

This study tested whether a smartwatch and weekly health coaching could help people caring for a loved one with dementia improve their sleep, activity, and mood. Twenty-one caregivers wore an Apple Watch to track their sleep and activity, received personalized feedback through a …

This study tested a website designed to help family members caring for someone with Alzheimer's disease. The program provided information about the illness, relaxation techniques, and a forum to talk with other caregivers. 49 caregivers took part to see if the program could lower…

This study tested a non-invasive brain stimulation method called tACS in 17 people with early to moderate Alzheimer's. The goal was to see if daily sessions over 2-4 weeks could safely reduce amyloid and tau buildup in the brain and improve memory and thinking. Participants recei…

This study tested whether a special light treatment could help people with mild cognitive impairment or early Alzheimer's disease. 25 participants who also had sleep problems and lived at home took part. The goal was to see if the light could improve thinking, sleep, and how the …

This study tested whether a gentle, non-invasive brain stimulation device used at home could help people with mild to moderate Alzheimer's disease. One hundred older adults used the device for 30 minutes a day, five days a week, for six months. The goal was to see if it improved …

This study tested a training program for people with mild to moderate Alzheimer's disease. The training used personal photos and videos to recreate familiar situations, aiming to improve orientation to time, place, and person. 126 participants were assigned to either the training…

This study tested a technology-based coaching and support program designed for Asian American midlife women (ages 40-65) who care for a family member with Alzheimer's disease. The program aimed to reduce caregiver stress and improve health. Fifty-four participants from Chinese or…

This study tested whether adding game-like features to a visual mapping app helps people with mild-to-moderate Alzheimer's or related dementias stay engaged and improves their quality of life. Sixty participants (each with a primary caregiver) used either the gamified app or the …

This study tested an 8-week telehealth program for people with Alzheimer's or related dementias living at home with a caregiver. The program used Zoom to teach caregivers how to adjust the home environment and daily routines to reduce challenging behaviors and improve the person'…

This study tested a sleep improvement program designed for both Alzheimer's patients and the people who care for them. 60 pairs (patient and caregiver) joined the study. The goal was to see if a tailored program could help both get better sleep and reduce related health problems.

This study tested a new, drug-free approach to help older adults with mild cognitive impairment or early Alzheimer's disease. The treatment combined a gentle electrical current applied to the head (tDCS) with cognitive training and a special light shined up the nose (near infrare…

This study tested new swallowing exercises for people with Alzheimer's disease or other dementias who have trouble swallowing. The goal was to reduce the amount of food or liquid left in the throat after swallowing, which can lead to pneumonia. 76 patients and their caregivers to…

This study tested a home-based device called Care4AD to help caregivers of people with Alzheimer's or dementia. The goal was to see if it could reduce caregiver stress and burden over three months. The study involved 33 caregivers and older adults with mild to moderate dementia.

This study tested whether doing paper-based cognitive training (like memory and attention exercises) could improve thinking and daily living skills in 70 Vietnamese patients with early Alzheimer's disease. Participants were aged 60-80 with mild symptoms. The goal was to see if th…

This study tested an experimental drug called AXS-05 to see if it can safely reduce agitation in people with Alzheimer's disease. About 408 participants took either the drug or a placebo for several weeks. The goal was to measure changes in agitation using a standard rating scale…

This study tested whether a special type of lighting could help people with Alzheimer's disease and type 2 diabetes sleep better and improve their health. 61 participants living in assisted living or nursing homes received either the special lighting or a regular light for 8 week…

This study tested a new in-home technology designed to help Spanish-speaking caregivers of people with dementia, Alzheimer's, or mild cognitive impairment. Six caregivers used the system for six months to see if it could lower their stress, anxiety, and loneliness. The goal was t…

This study tested a website called WeCareAdvisor that helps people caring for a loved one with dementia. The tool gives tips and strategies to manage challenging behaviors like aggression or wandering. Researchers wanted to see if it could lower caregiver stress and boost their c…

This study looked at the long-term safety and effectiveness of a drug called AXS-05 for treating agitation in people with Alzheimer's disease. 456 participants who had already been in earlier studies took the drug, and some later switched to a placebo to see if agitation symptoms…

This study tested whether wearable devices like Apple Watches could help reduce anxiety, burden, and loneliness in people caring for a family member with dementia or mild cognitive impairment. 63 caregivers in the U.S. used the technology at home for 6 months. The goal was to see…

This study tested a robot designed to engage older adults with mild cognitive impairment or Alzheimer's living in nursing homes. 142 participants were split into two groups: one continued usual activities, the other also spent time with the robot. Researchers measured changes in …

This study tested a new training program called SEMAT that teaches people with early-stage Alzheimer's or mild cognitive impairment how to use memory aids like calendars and lists. The goal was to help them stay independent in daily life. 68 older adults took part, and researcher…

This study looked at whether two special diets—the ketogenic diet and the Therapeutic Lifestyles Changes diet—could help improve thinking and memory in people with Alzheimer's disease. Researchers measured changes in cognitive performance over three months in 84 adults aged 50 to…

This study tested a special palliative care program for people with late-stage Alzheimer's or related dementias and their family caregivers. The program started during a hospital stay and included caregiver education and support after discharge. Researchers wanted to see if it co…

This study tested whether a long-term exercise program could help people with dementia living in nursing homes maintain their ability to do daily tasks like bathing and dressing. 140 participants were split into an exercise group and a social activity group. The goal was to see i…

This study tested a new drug called SAGE-718 in 26 people with mild memory or thinking problems due to Alzheimer's disease. The main goal was to see if the drug is safe and tolerable, and to check if it helps with cognitive and mood symptoms. Participants took the drug and were m…

This study looked at whether combining exercise with a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) can help improve memory in people with mild cognitive impairment or Alzheimer's disease. Researchers tested 60 adults aged 50 and older …

This study looked at whether spironolactone, a blood pressure medication, is safe for older African Americans with mild memory loss or early dementia. Twenty-five participants took either the drug or a placebo for one year. Researchers tracked side effects and measured thinking s…

This small study tested whether a dietary supplement called citicoline could improve sleep and thinking in people with Alzheimer's disease. Twenty participants took the supplement, and researchers measured sleep quality and daytime sleepiness using questionnaires. The goal was to…

This study looked at whether listening to emotionally meaningful music can improve mood and alertness in people with moderate to severe Alzheimer's disease. Ten participants were exposed to special music and a control condition. Researchers measured changes in overall well-being …

This study tested whether a melt-in-mouth version of the Alzheimer's drug memantine is more satisfying for caregivers than the standard tablet. About 105 patients with moderate to severe Alzheimer's took one form for two months, and their primary caregivers filled out a satisfact…

This study tested whether levetiracetam, a medication used for epilepsy, can reduce abnormal brain overactivity and improve memory and thinking in people with early Alzheimer's disease. Fifty-eight participants received the drug or a placebo to see if it calms brain signals and b…

This study tested a web-based app called Gotcha! that helps people with mild-to-moderate dementia practice remembering names of people they know. 48 participants used the app at home for about 30 minutes each day over 6 weeks. The goal was to see if the app could improve name rec…

This study tested whether a dietary supplement called citicoline could improve sleep and thinking in 100 older adults with mild cognitive impairment (MCI), a condition that can lead to Alzheimer's disease. Participants took citicoline or a placebo for several months. Researchers …

This study tested a video-based program called Tele-STELLA that helps family caregivers of people with Alzheimer's or related dementias. The program connects caregivers with a guide to find ways to reduce upsetting behaviors in their loved ones. The goal was to lower caregiver st…

This small study tested whether a home-use brain stimulation device called tDCS is safe and acceptable for people with Alzheimer's who have behavioral symptoms like agitation or apathy. Only 3 participants took part, each with a caregiver. The goal was to see if families could us…

This study tested whether hearing aids could improve thinking, behavior, and quality of life in people with mild to moderate Alzheimer's disease who also have hearing loss. 51 participants were split into two groups: one got active hearing aids right away, the other started with …

This study tested a program designed to help veterans with Alzheimer's disease or traumatic brain injury and the family or friends who care for them. The goal was to see if the program could improve quality of life and reduce caregiver burden. About 236 veterans and their caregiv…

This study tested a program called UPLIFT-AD that brings palliative care—a type of care focused on comfort and quality of life—into nursing homes for people with Alzheimer's disease. Over 1,300 residents, their families, and nursing home staff took part. The program trained staff…

This study tested a new website tool called WeCareToFeedDysphagia to see if it helps reduce stress for people caring for a loved one with dementia and trouble swallowing. 80 caregivers took part, with some getting access to the tool and others getting standard support. The goal w…

This study looked at whether dual-task training—exercises that mix physical movement with thinking tasks—can improve balance, reduce fear of falling, boost thinking skills, and enhance quality of life in people with mild to moderate Alzheimer's disease. 34 participants completed …

This study examined whether gum disease and Alzheimer's disease are connected through blood markers. Researchers measured gum health and blood counts in 100 adults over 50 who did not smoke or drink alcohol. The goal was to understand the relationship, not to test a treatment.

This study involved 100 adults aged 50-80 with normal cognition or mild impairment. Researchers took 10 weekly blood samples from each person to see how a key Alzheimer's biomarker, pTau-217, changes over time. The goal was to understand normal fluctuations and identify unexpecte…

This study tested whether specially designed tablet games, called VibrantMinds, can measure and improve cognitive skills in older adults with mild cognitive impairment or dementia. 26 participants aged 65 and older played the games, and researchers tracked changes in thinking, mo…

This study examined 186 people with different types of dementia (Alzheimer's, Lewy body, frontotemporal, and corticobasal) plus healthy volunteers to see if subtle brain signs, called neurological soft signs, differ between groups. Participants took simple movement and coordinati…

This study looked at whether specially trained senior volunteers can help families caring for someone with Alzheimer's or dementia. The goal was to connect families with community services and improve their interactions with doctors. 44 people with dementia and their caregivers t…

This study tested an online program called "Safety in Dementia" for caregivers of people with dementia who have access to firearms. The goal was to see if the program helps caregivers feel more prepared and confident in making safety decisions. 500 caregivers from across the US t…

This study tested whether an online platform can effectively share Alzheimer's gene and biomarker test results with participants, compared to a video call with a healthcare provider. 681 adults took part, and researchers measured their anxiety, distress, and understanding of the …

This study looked at how older adults with and without Alzheimer's disease move in time to music. Researchers wanted to understand if this ability to synchronize movements with a beat is linked to emotional state and nonverbal communication. The study involved 240 participants an…

This study tested a new way to stimulate the brain using two gentle techniques (tACS and iTBS) to improve working memory in 30 healthy adults. The goal was to see if these methods could strengthen brain waves linked to memory, which are often weak in Alzheimer's disease. While no…

This study tested whether a gentle electrical current applied to the scalp (called tACS) at a specific frequency (40 Hz) could strengthen brain waves linked to memory in 30 healthy older adults aged 50-80. The goal was to see which brain areas to stimulate for the best effect, wh…

This study looked at how older adults make decisions about where to live and how to get care if they develop memory loss or Alzheimer's disease. Researchers followed 293 participants over time to see if they had made plans for staying at home or moving to a care facility. The goa…

This study looked at how menopause affects brain chemistry and Alzheimer's risk in 120 postmenopausal women aged 50-70. Researchers used brain scans and memory tests to see how the brain's cholinergic system responds to hormone changes. The goal is to understand why some women ha…

This study looked at whether shining a special light on the head (called transcranial photobiomodulation) can improve blood flow in the brain and help with thinking skills. Researchers tested 24 adults aged 18 to 80. The goal was to understand how the light affects brain health, …

This study looked at whether thinning of the retina (the back part of the eye) can be a sign of Alzheimer's disease. Researchers compared eye scans from 55 people with Alzheimer's, Lewy body disease, and healthy individuals. The goal was to see if measuring retinal layers could h…

This study looked at whether certain variations in the ABCB1 gene make it harder for the brain to clear a protein called amyloid beta, which is linked to Alzheimer's disease. Researchers compared 510 people with and without Alzheimer's to see if these gene changes are more common…

This study looked at whether daily breathing exercises could improve memory and reduce Alzheimer's risk in healthy adults aged 50-70. Participants did brain training and either relaxing or alertness-boosting breathing exercises for 10 weeks. Researchers measured changes in blood …

This study looked for chemical markers in blood and urine that could help detect Alzheimer's disease early. Researchers compared samples from 95 people with normal aging, mild cognitive impairment, or Alzheimer's. The goal is to develop a simple test that catches the disease befo…

This study looked at whether a specific gene variation (CR1) that affects a blood protein makes people more likely to develop Alzheimer's disease. Researchers compared 200 people—some with Alzheimer's and some without—to see if the gene difference was more common in those with th…

This study looked at how a week of daily meditation affects blood markers linked to Alzheimer's disease in healthy adults aged 18-35. Participants meditated at home and gave blood samples before and after. The goal was to see if meditation could change these markers, not to treat…

This study aimed to find very early signs of Alzheimer's disease in the brain before memory problems start. Researchers used brain scans to measure changes in areas like the hippocampus in 304 retired farmers aged 65 and older who had no reported thinking difficulties. The goal w…

This study tested a program to help nursing home staff better discuss and record care preferences for people with Alzheimer's or related dementias. The goal was to reduce unwanted hospital visits by making sure patients' wishes are known and followed. Over 47,000 residents in nur…

This study looked at how Latino adults in New York City react to learning their genetic risk for Alzheimer's disease. 374 participants either received risk info based on family history alone or also got their APOE gene test results. Researchers measured distress, memory, and beha…

This study looked at how well a new type of brain scan (PET) can tell apart different memory and thinking disorders, including Alzheimer's disease, frontotemporal degeneration, Lewy body dementia, and some psychiatric conditions. Researchers compared the new scan to a standard on…

This study followed 544 older adults in committed relationships for three years to understand how their relationship affects their mental health when one partner has Alzheimer's disease. Both partners answered questionnaires about their emotional health, caregiving roles, and qua…

This study looked at 30 healthy older adults (ages 55-75) to see if early brain changes in a region called the locus coeruleus can be detected before Alzheimer's symptoms appear. Researchers used brain scans, sleep tests, and spinal fluid analysis to measure how these changes aff…

This study looks at how sleep is disturbed in people with Alzheimer's disease. Researchers want to learn how changes in daily sleep-wake cycles affect daytime alertness. The study involves 70 participants, including those with memory problems and healthy volunteers. They will kee…

This study explored whether a medication used for sleep can boost the brain's natural waste-clearing system, called the glymphatic system, in healthy older adults. The goal was to see if this approach could help remove harmful proteins linked to Alzheimer's disease. 31 participan…

This study looked at 46 older adults with Alzheimer's disease to see if age-related hearing loss is connected to difficulty finding words. Participants completed a computer test for word-finding and a hearing questionnaire. The goal was to better understand how hearing and langua…

This study tested a digital tool that scans electronic health records to find older adults who may have undetected memory problems or early Alzheimer's disease. Over 3,400 patients aged 65 and older from primary care clinics took part. The goal was to see if the tool could help i…

This study tested a new version of the drug NPT 2042 to see how well it is absorbed compared to the original version. Eight healthy adults took both forms, and researchers measured drug levels in their blood. The goal was to gather information, not to treat any disease.

This study looked at how dementia with Lewy bodies (DLB) changes a person's sense of self, including memory and self-concept. Researchers compared 61 older adults with DLB, Alzheimer's disease, and healthy aging using interviews and brain scans. The goal was to understand which b…

This study collected blood samples from 26 people with early-onset Alzheimer's disease and their close family members. Researchers analyzed DNA and RNA to find biological markers that could help doctors diagnose and treat the disease earlier. The goal was to better understand how…

This study looked at how deep sleep and race might influence Alzheimer's risk. Researchers monitored sleep in 210 healthy older adults (ages 60-75) of African-American and white backgrounds. They measured brain amyloid levels, a marker for Alzheimer's, to see if poor sleep qualit…

This study tested two ways of training long-term care workers in Minnesota to provide better care for LGBTQ+ residents with Alzheimer's or dementia. Over 760 staff members took part in either in-person or online training. The goal was to see if the training improved staff knowled…

This study looked at how a person's genes (APOE type) and compounds from plants affect gut bacteria. 49 healthy adults donated saliva and stool samples. Researchers analyzed the bacteria's response to plant extracts in a lab model. The goal was to understand links between diet, g…

This study looked at how the brain and body communicate in 30 people, including healthy volunteers and those with conditions like autism, ADHD, Asperger's, Alzheimer's, Parkinson's, and Fragile X. Participants did natural movements like walking and pointing, and breathed slowly w…

This study collected brain wave (EEG) data from 29 people at different stages of Alzheimer's disease, from those with no symptoms to severe dementia. Researchers also included people with a related condition called dementia with Lewy bodies. The goal was to see if EEG patterns co…

This study aimed to create a communication tool to help people with Alzheimer's or dementia and their caregivers discuss and plan for future medical care. Researchers worked with 38 participants to see if the tool improved their readiness to make advance care plans. The goal was …

This study looked at how well older adults with early-stage Alzheimer's can drive in real traffic. Researchers compared 60 drivers aged 70+ (half with Alzheimer's, half healthy) to find common mistakes and suggest ways to keep them driving safely. No treatment or cure was tested;…

This study tested a simple idea: sending gentle reminders (nudges) to doctors and caregivers to help reduce or stop certain high-risk medications in people with dementia. Researchers worked with 250 patients aged 65 and older to see if this approach was practical and could be mea…

This study tested whether sending educational materials to caregivers of people with Alzheimer's disease could reduce the use of risky medications like sedatives and antipsychotics. Over 11,000 older adults with Alzheimer's took part. The goal was to see if simple mailings could …

This study looked at how people with Alzheimer's disease or a type of frontotemporal dementia recall personal memories. Researchers analyzed whether memories were specific events or more general. The goal was to better understand memory loss patterns, not to test a treatment. 39 …

This study looked at whether obstructive sleep apnea (OSA) might help cause Alzheimer's disease. Researchers studied 182 older adults aged 65-85, some with and some without sleep apnea, using brain scans and breathing tests. The goal was to understand how sleep disruptions from a…

This study looked at whether certain brain measurements can predict how well people with Alzheimer's disease respond to the drug memantine. Fifty-three participants took memantine for 24 weeks, and researchers tracked changes in thinking and behavior. The goal was to find biomark…

This study tested a new computer system that uses artificial intelligence to help doctors better diagnose and treat complex brain disorders like dementia, epilepsy, and sleep problems. Researchers collected information from 635 people, including healthy volunteers, to see if the …