Can a website replace your doctor for Alzheimer's risk news?
NCT ID NCT06459583
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether an online platform can effectively share Alzheimer's gene and biomarker test results with 681 participants, compared to a video call with a healthcare provider. The goal was to see if the self-guided method causes similar levels of anxiety, distress, and understanding. This research helps improve how risk information is delivered without overwhelming patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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681 people
The number who actually took part.
- Started
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Oct 2024
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Access to the internet and an internet-enabled device. * Participant is able to provide informed consent as shown by correctly answering questions administered by the study coordinator during the electronic consenting process that assess understanding of consent form content. * Participant is willing and has the ability to fully comply with study procedures defined in this protocol. * Written and spoken fluency in the English. * Participant agrees to undergo a blood draw for collection of a blood sample for future testing and repository storage. Exclusion Criteria: * Participant reports prior knowledge of APOE genotype. * Lack of psychological readiness to receive AD gene and biomarker information as indicated by: 1. obtaining a score of 10 or greater on the Patient Health Questionnaire - 9 (PHQ-9) AND/OR 2. responding yes on any of the suicidal ideation questions extracted from the abbreviated Columbia Suicide Severity Scale (C-SSRS) or AD Specific Suicidality Questions. * Presence of current major psychiatric illness, e.g., psychosis, bipolar disorder, PTSD * Communication difficulties such as: 1. Uncorrected or uncompensated hearing and/or vision impairment. 2. Uncorrected or uncompensated speech defects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Accellacare Clinical Research Site 01
Bristol, Tennessee, 37620, United States
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Accellacare Clinical Research Site 02
Mt. Pleasant, South Carolina, 29464, United States
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Other studies related to the condition(s) this trial covers.
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