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Can a website replace your doctor for Alzheimer's risk news?

NCT ID NCT06459583

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether an online platform can effectively share Alzheimer's gene and biomarker test results with 681 participants, compared to a video call with a healthcare provider. The goal was to see if the self-guided method causes similar levels of anxiety, distress, and understanding. This research helps improve how risk information is delivered without overwhelming patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

681 people

The number who actually took part.

Started

Oct 2024

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Access to the internet and an internet-enabled device. * Participant is able to provide informed consent as shown by correctly answering questions administered by the study coordinator during the electronic consenting process that assess understanding of consent form content. * Participant is willing and has the ability to fully comply with study procedures defined in this protocol. * Written and spoken fluency in the English. * Participant agrees to undergo a blood draw for collection of a blood sample for future testing and repository storage. Exclusion Criteria: * Participant reports prior knowledge of APOE genotype. * Lack of psychological readiness to receive AD gene and biomarker information as indicated by: 1. obtaining a score of 10 or greater on the Patient Health Questionnaire - 9 (PHQ-9) AND/OR 2. responding yes on any of the suicidal ideation questions extracted from the abbreviated Columbia Suicide Severity Scale (C-SSRS) or AD Specific Suicidality Questions. * Presence of current major psychiatric illness, e.g., psychosis, bipolar disorder, PTSD * Communication difficulties such as: 1. Uncorrected or uncompensated hearing and/or vision impairment. 2. Uncorrected or uncompensated speech defects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Accellacare Clinical Research Site 01

    Bristol, Tennessee, 37620, United States

  • Accellacare Clinical Research Site 02

    Mt. Pleasant, South Carolina, 29464, United States

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