Alzheimer's caregivers get help to cut dangerous pills
NCT ID NCT06368115
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether mailing educational materials to caregivers of people with Alzheimer's could reduce the use of risky medications like sedatives and antipsychotics. Over 11,000 older adults with Alzheimer's took part. The goal was to see if this simple approach could make medication safer without changing doctor visits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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11,375 people
The number who actually took part.
- Started
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Jul 2024
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Patient Inclusion Criteria: 1. Diagnosis of AD/ADRD based on a combination of AD/ADRD codes or treatment with a pharmacologic therapy used for AD (e.g., donepezil, rivastigmine, galantamine, and memantine) in the 365 days prior to or on cohort entry date. 2. Evidence of potentially inappropriate prescribing with antipsychotics, sedative-hypnotics, and strong anticholinergics within the past 3 months 3. Age ≥50 years of age as of cohort entry date 4. Continuous medical and pharmacy insurance coverage for at least the prior year Patient Exclusion Criteria: 1. Evidence of residing in a nursing home or skilled nursing facility or receiving palliative care. 2. Incomplete/missing prescriber ID or incomplete contact information for either patient or prescribing provider. 3. On "do not contact" list Provider Inclusion Criteria: 1\. Prescribing provider associated with most recent prescribing of target drug.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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UMass Chan Medical School
Worcester, Massachusetts, 01605, United States
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Other studies related to the condition(s) this trial covers.
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