Lifestyle overhaul may shield aging brains from memory loss

NCT ID NCT03688126

Completed Prevention Sponsor: Wake Forest University Health Sciences Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 29 times

Summary

This study tested whether a combination of physical exercise, mental challenges, a healthy diet, and social activities can protect memory and thinking in older adults at risk for Alzheimer's. Researchers enrolled 2,000 sedentary Americans with low diet scores but no current memory problems. The goal was to see if these lifestyle changes could slow or prevent cognitive decline.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Chicagoland--Advocate Aurora Health

Downers Grove, Illinois, 60068, United States
Chicagoland--Rush

Chicago, Illinois, 60304, United States
Houston

Houston, Texas, 77030, United States
New England--Rhode Island

Providence, Rhode Island, 02906, United States
North Carolina

Winston-Salem, North Carolina, 27157, United States
Northern California

Sacramento, California, 95616, United States

Conditions

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ALZHEIMER DISEASE