Karolinska Institutet

This study looks at 350 women under 39 with advanced endometriosis (stage III-IV) who want to get pregnant. It compares two approaches: having surgery to remove endometriosis tissue before starting IVF, or going straight to IVF without surgery. The goal is to see which method lea…

This study tests a new digital tool called Evira that helps families track a child's weight at home and message their clinic easily. About 680 children aged 4 to 17 with obesity will use the app alongside their usual lifestyle treatment. The goal is to see if the app helps kids l…

This study explores whether group-based metacognitive therapy (MCT) is practical and well-liked by adults with PTSD in regular psychiatric care. About 30 participants will attend group sessions, and researchers will track how many complete the treatment, report side effects, and …

This study tests whether an online cognitive behavioral therapy (CBT) program can help children aged 8-17 with asthma who also feel anxious or worried about their condition. The therapy is designed to improve quality of life, reduce anxiety, and help control asthma symptoms. Abou…

This study tests if an online therapy program (CBT) can help people who had a heart attack feel less anxious about their heart and improve their quality of life. About 176 adults who had a heart attack at least 6 months ago and still have significant heart-related fear will parti…

This study is testing a stepped care approach to help children aged 8-16 who have trouble controlling anger or show defiant or aggressive behavior. The program starts with a brief online parenting support course. If more help is needed, families can try a virtual reality (VR)-ass…

This study tests an internet-based therapy called IERITA for teenagers aged 13-17 who have hurt themselves on purpose (nonsuicidal self-injury). The therapy helps teens learn to manage their emotions. The goal is to see if this online approach is practical and helpful, so it can …

This study compares two groups of women having robotic hysterectomy: one group goes home the same day, the other stays overnight. Researchers want to see if same-day discharge leads to faster recovery and similar safety. About 300 women with benign conditions or endometrial cance…

This study compares two ways of giving surfactant, a medicine that helps premature babies' lungs work better. The standard method uses a breathing tube placed into the windpipe, which can be uncomfortable and risky. The newer method uses a soft mask placed in the throat. The goal…

This study looks at how the bacteria and natural chemicals in couples' bodies might influence the success of IVF treatment. Researchers will collect samples from 1,000 couples and track outcomes like pregnancy, miscarriage, and live birth. The goal is to find patterns that could …

This study looks at how red blood cells (RBCs) influence heart health, especially in people with type 2 diabetes. Researchers will collect RBCs from 500 participants (those with diabetes, heart attack survivors, and healthy volunteers) and test them in the lab to understand how t…

This study looks at 100 children with tracheostomies to see if symptoms noticed by parents or pediatricians can predict serious airway complications. Researchers compare these reports with findings from routine camera exams (endoscopy) done under anesthesia. The goal is to unders…

This study follows up with people who had jaw joint surgery about 10 years ago to see if the benefits seen at 6 months still last. Researchers will measure jaw opening, pain, and disability, and take a special X-ray to check for joint wear. The goal is to understand how well surg…