Second look inside the kidney: could repeat biopsies save lupus Patients' kidneys?
NCT ID NCT04449991
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looks at whether doing a repeat kidney biopsy one year after starting treatment for lupus nephritis can help doctors decide if more treatment is needed. Half of the 206 participants will get the repeat biopsy, and the other half will follow standard care. The goal is to see if the biopsy group has better kidney function and fewer relapses over two to five years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could show that repeat biopsies help doctors tailor treatment to reduce kidney damage in lupus nephritis patients.
- What could go wrong
- This is an observational/procedural study, not testing a new drug. The benefit of repeat biopsy is uncertain, and biopsies carry small risks like bleeding or infection.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Karolinska University Hospital
RECRUITINGStockholm, 17676, Sweden
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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