Surgery before IVF may boost baby chances for endometriosis patients

NCT ID NCT07240363

Recruiting now Disease control Sponsor: Karolinska Institutet Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two approaches for women under 39 with advanced endometriosis who want to get pregnant: having surgery to remove endometriosis lesions before IVF, or going straight to IVF. The goal is to see which leads to more live births within three years. The trial will enroll 350 women across Sweden and track pregnancy rates, complications, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Endometriosis surgery (laparoscopic excision) followed by IVF
What this could lead to: If surgery before IVF works better, it could become the standard approach to help women with advanced endometriosis have a baby.
What could go wrong: This is the first large trial on this question, so results are uncertain. Surgery carries risks like infection or organ damage, and may not improve pregnancy chances.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endometriosis infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIOSIS INFERTILITY ASSISTED REPRODUCTIVE TECHNOLOGY

Contacts and locations

Locations

Sahlgrenska University Hospital
NOT_YET_RECRUITING

Gothenburg, Västra Götaland County, Sweden
Skåne university hospital, Malmö
NOT_YET_RECRUITING

Malmö, Sweden
Sodersjukhuset
RECRUITING

Stockholm, Stockholm County, 11883, Sweden
Uppsala University Hospital, Uppsala
NOT_YET_RECRUITING

Uppsala, Sweden

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