Could a blast of cold air save your brain after a heart attack?
NCT ID NCT06025123
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether cooling the brain quickly after a cardiac arrest (using a special nasal device) and then keeping the body cool for 24 hours helps more people survive with full brain function. About 1,000 adults aged 18-79 who have a shockable heart rhythm will be randomly assigned to either rapid cooling or standard care. The main goal is to see if more people in the cooling group are alive and neurologically healthy 90 days later.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU Saint-Pierre
RECRUITINGBrussels, Belgium
Contact Email: •••••@•••••
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Department of Anesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
NOT_YET_RECRUITINGMilan, Italy
Contact Email: •••••@•••••
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Erasme University Hospital
RECRUITINGBrussels, Belgium
Contact Email: •••••@•••••
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Europe Hospitals St Elizabeth
RECRUITINGBrussels, Belgium
Contact Email: •••••@•••••
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Hospital Universitario La Paz
RECRUITINGMadrid, Spain
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Karolinska University Hospital
RECRUITINGStockholm, Sweden
Contact Email: •••••@•••••
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Ljubljana University Medical Centre
RECRUITINGLjubljana, Slovenia
Contact Email: •••••@•••••
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San Carlos Clinical Hospital
RECRUITINGMadrid, Spain
Contact
Contact
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Södersjukhuset
RECRUITINGStockholm, Sweden
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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University Hospital Freiburg
RECRUITINGFreiburg im Breisgau, Germany
Contact Email: •••••@•••••
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University Hospital Vienna
NOT_YET_RECRUITINGVienna, Austria
Contact Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Heart device data may unlock secrets of rare heart muscle disease
- Chilled saline infused directly into brain during stroke treatment may limit damage
- Could a Heart-Lung machine at the scene of a cardiac arrest double survival?
- Dispatcher training could boost cardiac arrest survival