Exercise may boost Chemo's power against breast cancer

NCT ID NCT05184582

Recruiting now Disease control Sponsor: Karolinska Institutet Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This trial tests whether supervised exercise during chemotherapy can help eliminate breast cancer more effectively. 712 participants will be randomly assigned to either a structured exercise program or usual care. The main goal is to see if exercise increases the rate of complete cancer disappearance at surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: supervised high-intensity interval and resistance training
What this could lead to: If it works, this could show that adding exercise to chemotherapy helps eliminate more breast cancer before surgery.
What could go wrong: This is an early-stage study testing a behavioral intervention, not a drug. Results may not show a clear benefit, and exercise may not be feasible for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

Cabrini Health
NOT_YET_RECRUITING

Melbourne, Australia
Capio St Görans Hospital
RECRUITING

Stockholm, Sweden
Edinburgh Napier University
NOT_YET_RECRUITING

Edinburgh, Scotland, United Kingdom
Helsinki University Hospital
RECRUITING

Helsinki, Finland
Karolinska University Hospital
RECRUITING

Stockholm, Stockholm County, 17176, Sweden
Royal Marsden
NOT_YET_RECRUITING

London, United Kingdom
Sahlgrenska University Hospital
RECRUITING

Gothenburg, Sweden
Skaraborgs sjukhus
RECRUITING

Lidköping, Sweden
Southern General Hospital
RECRUITING

Stockholm, Sweden
Sundsvall Hospital
RECRUITING

Sundsvall, Sweden
Turku University Hospital
NOT_YET_RECRUITING

Turku, Finland
Umeå University Hospital
RECRUITING

Umeå, Sweden
Västmanlands Hospital
RECRUITING

Västerås, Sweden

More trials for these conditions

Other studies related to the condition(s) this trial covers.