SLEEP

This study tests a 24-week program called Black Impact for Black men with below-ideal heart health. Participants will take part in weekly physical activity, health education, and work with a coach and trainer. The goal is to see if the program improves heart health and reduces st…

This study is testing whether wearable devices like a headband, a movement tracker, and a smartphone app can accurately measure sleep stages (like deep sleep and REM) compared to the standard sleep lab test called polysomnography. The researchers will first test the devices on 48…

This study checks if wearable devices like movement sensors, headbands, and pulse oximeters can accurately track sleep stages in children and teens aged 3 to 18. Results will be compared with standard sleep lab tests to see if these gadgets can help diagnose sleep problems more e…

This study tests whether a common sleep medication, suvorexant, can slow the buildup of a protein in the brain linked to Alzheimer's disease. Researchers will enroll 200 healthy adults aged 65 and older who do not have memory problems. Participants will take either the sleep aid …

This pilot study tests a specially designed sleep program for family caregivers who have trouble sleeping. The program combines cognitive behavioral therapy, mindfulness, and caregiving tips. Researchers want to see if it improves sleep regularity, timing, efficiency, and daytime…

This study tests whether a magnesium supplement called Magnesium-L-Threonate (MgT) can improve sleep quality and reduce pain in people recovering from total knee or hip replacement. Researchers will enroll 64 adults having surgery at the University of Miami Hospital. Participants…

This study is testing whether a special probiotic called ExoBDNF can help improve thinking skills, sleep, and mood in adults aged 18 and older. About 50 volunteers will take the supplement daily for 8 weeks. Researchers will measure changes in memory, concentration, and overall m…

This study tests whether giving prebiotics (a type of fiber) every day for several weeks can improve mood, sleep, and thinking in healthy 3-5 year olds who don't eat enough fiber. About 106 children will take either a prebiotic or a placebo powder mixed into food. Parents will re…

This study tests whether adding bright light therapy, methylphenidate, or melatonin to cognitive behavior therapy (CBT) can improve sleep, fatigue, anxiety, and depression in 188 adults with advanced cancer. Participants will receive CBT plus one of the add-on treatments or a pla…

This study is testing whether taking a collagen supplement for 8 days can improve quality of life, appetite, mood, and blood sugar control in overweight or obese adults aged 18-65. Participants will take the supplement or a placebo, fill out questionnaires, and wear a continuous …

This study tests whether taking ETAS® daily for 12 weeks can improve memory, mood, and brain function in healthy adults aged 60 to 80 who have mild memory complaints. Participants will be randomly assigned to receive either ETAS® or a placebo, and will undergo memory tests, brain…

This study looks at whether a supplement called MyVitalC (ESS60 in extra virgin olive oil) can improve sleep and reduce headaches. About 100 adults will track their sleep and headaches for 4 weeks without the supplement, then take it daily for 6 weeks and report any changes. The …

This study is testing whether a special bed cooling system (the Chilipad Dock Pro) can improve sleep quality and overall well-being. About 100 adults who can read English and live in the US will use the system at home and report their sleep and health through surveys. People with…

This pilot study is testing a sleep health program designed for couples. The goal is to see if it can improve sleep and lower blood pressure in partners. 50 couples will participate in an 8-week program that includes sleep coaching, goal-setting, and monitoring. The study will al…

This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) can improve sleep quality in healthy adults aged 40 to 60. Participants will take either the supplement or a placebo for 8 weeks, and their sleep will be measured with brain wave monitoring.…

This study tests whether a daily nutritional supplement can improve sleep quality in adults aged 35-65 who have mild sleep problems. About 140 participants will take either the supplement or a placebo for several weeks, and sleep will be tracked using a special ring and questionn…

This study tests whether daridorexant, a sleep aid, can safely improve total sleep time in 62 adults aged 60-85 with mild cognitive impairment or mild-to-moderate Alzheimer's disease who also have chronic insomnia. Participants will have their sleep measured in a lab. The goal is…

This 30-day study tests SleepWhale Natural Sleep Drops (Extra Strength) in 100 adults to see if they improve sleep quality, reduce daytime sleepiness, and boost resilience. Participants will complete surveys about their sleep, fatigue, and well-being. The study is for US resident…

This study tests whether hemp-derived CBD (with or without THC) can reduce harm from cannabis use in adults aged 60 and older who have sleep, anxiety, depression, or pain issues. Participants will be randomly assigned to take CBD+THC, CBD alone, or a placebo for 8 weeks. The goal…

This study tests a sleep-focused program (TranS-C) plus bright light therapy in 90 teens aged 12-18 with depression and sleep problems. Participants either get the full program or just sleep feedback. The goal is to see if the approach is acceptable and helps ease depression and …

This study tests whether a special type of lighting that changes throughout the day can improve sleep, daily rhythms, and well-being in frail older adults (65+) staying in the hospital. Researchers will measure changes in melatonin levels and sleep patterns. The goal is to help p…

This study tests whether taking 1 ml of reishi mushroom extract daily before bed can improve sleep quality and reduce stress. About 100 adults who can read English and live in the US will participate. The study measures sleep, fatigue, and stress using questionnaires. It is not a…

This study tests two school-based programs to improve sleep in teens aged 12-18 who have sleep problems like insomnia or poor sleep quality. Researchers will compare a standard sleep education class with a more personalized step-by-step program. The goal is to see which approach …

This study tests whether immersive virtual reality exercise can reduce pain, improve shoulder function, sleep, and thinking skills in people with mild to moderate frozen shoulder (grade 1-2). About 36 adults aged 18-64 who are new to physical therapy will use VR headsets to do ga…

This study tests a comfort program for children aged 5-10 in the pediatric intensive care unit (PICU). The program includes listening to their mother's voice, dimming lights, and using a weighted blanket, along with regular nursing care. Researchers want to see if this helps chil…

This study tests a brief sleep program for depressed adolescents aged 12-18 who get too little sleep or have irregular sleep patterns. The program uses two counseling sessions and a smartphone app to teach healthy sleep habits. Researchers will see if the program is practical and…

This study tests whether a sleep bundle—including a sleep mask, ear plugs, and a noise machine—can help adults sleep better after heart surgery. Twenty participants will either receive the sleep bundle or standard care. The main goal is to see if the study is practical for a larg…

This study looks at whether a gentle exercise program called Body Awareness Therapy (BAT) can improve balance, sleep, and mental health in young adults (ages 20-30) who feel very stressed. About 62 people will either do BAT in a group twice a week for 8 weeks or be in a control g…

This study is testing whether cognitive behavioral therapy for insomnia (CBT-I) can improve sleep, reduce brain injury symptoms, and help people with mild traumatic brain injury (mTBI) get back to their daily activities. Researchers will enroll 15 adults with mTBI and sleep probl…

This study is testing whether taking a daily saffron extract supplement (30 mg) for six weeks can improve sleep quality in middle-aged adults who have mild-to-moderate sleep problems. Researchers will measure sleep using a wrist-worn device and track other factors like mood and s…

This study compares two types of talk therapy—cognitive behavioral therapy and mindfulness—to see which works better for insomnia in people who have had a mild to moderate traumatic brain injury and also have post-traumatic stress symptoms. 360 participants will receive 6 therapy…

This study tests whether a custom mouthpiece that gently moves the lower jaw forward during sleep can improve sleep quality, heart rate patterns, and blood oxygen levels. Twenty-four healthy adults aged 40-65 will wear both the active device and a placebo device for several weeks…

This study looks at whether extending the nightly fasting period (not eating for a longer stretch each night) can improve sleep, thinking, and quality of life in breast cancer survivors. Researchers will compare this approach to health education alone. The study involves 60 femal…

This study tests whether morning bright light therapy can improve sleep and brain function in 105 adults recovering from opioid use disorder. Participants on stable medication will receive either bright or dim light for 30 minutes daily over two weeks. Researchers will measure sl…

This study is testing whether a daily supplement called AGZ can help adults aged 25-59 who have trouble sleeping feel more relaxed in the evening, sleep better, and wake up feeling refreshed. About 300 people will take AGZ or a placebo for 30 days and answer questionnaires about …

This study is testing whether a low dose of clonidine, a drug usually used for high blood pressure, can improve sleep and reduce PTSD symptoms in military veterans. About 32 veterans with PTSD will take the drug and be monitored for 6 weeks. The goal is to see if this safe, affor…

This study tests whether a sleep health program can help U.S. Marines sleep better and feel mentally healthier. About 860 Marines will be randomly assigned to one of five groups to receive different versions of the program. Researchers will use surveys and wearable sleep trackers…

This study is testing whether a daily snack rich in plant chemicals and fiber can improve common perimenopause symptoms like hot flashes, mood changes, and sleep problems. Researchers will also check if the snack changes gut bacteria, which might be linked to symptom relief. The …

This study looks at whether doing gentle, adapted physical activity every day can improve sleep in children aged 5 to 16 who are being treated for blood cancer. About 30 children will take part, and their sleep quality will be tracked by parents and a wearable device. The goal is…

This study looks at how sensory sensitivities affect sleep and emotions in autistic children ages 6-10. Researchers will test a special bedtime routine designed to lower arousal levels in children who are overly sensitive to sensory input. The goal is to see if this routine impro…

This study tests two different behavioral approaches to see which works better for improving mood, sleep, and reducing suicide risk in adults aged 55 and older who have depression. About 420 participants will wear a sleep tracker and complete surveys over 8 weeks. The goal is to …

This study brings together 1000 teenagers (ages 12-18) from disadvantaged areas in Denmark, the Netherlands, Nigeria, and South Africa with researchers and local leaders. Together, they will design and test changes to their neighborhoods—like parks and school spaces—to help teens…

This study looks at how things like air quality, noise, and light in hospital wards affect patients' sleep. Researchers will measure these factors and track the sleep of 120 adult patients who stay at least two nights. The goal is to understand the hospital environment better and…

This early-stage study at Stanford tests whether giving magnetic brain stimulation during sleep is safe and practical for people with major depression. Fifteen adults who have not gotten better with at least one antidepressant will receive both real and fake stimulation in separa…

This study looks at whether researchers can successfully measure sleep in adult video game players who do not have a gaming disorder. It will compare regular gamers to non-gamers and test tools like sleep trackers and urine samples. The goal is to see if a larger study on gaming …

This study looks at how pregnant women sleep, focusing on the positions they spend the most time in and how often they snore. About 500 women who are at least 28 weeks pregnant will use a sleep monitor at home. The goal is to learn more about sleep patterns during pregnancy and s…

This study aims to understand how lifestyle factors like diet, exercise, stress, and sleep relate to heart health. Researchers will collect data from 100 adults and children using questionnaires and simple health measurements like blood pressure and weight. No treatments or inter…

This study looks at why many people have trouble sleeping after planned surgery. Researchers will ask 1,000 adults about their sleep quality and drowsiness the night after their operation. The goal is to find out what factors—like pain, fear, or hospital routines—affect sleep, so…

This study looks at how cannabis use and stopping it affect sleep, daily body rhythms, and sensitivity to light in healthy young adults aged 18-25. Researchers will compare regular cannabis users with non-users using sleep monitors, light tests, and pupil measurements. The goal i…

This study looks at whether improving deep sleep can help protect against Alzheimer's disease. Researchers will ask 116 older adults (ages 65-85) with mild sleep issues to spend less time in bed to naturally deepen their sleep. They will then measure changes in memory, brain acti…

This study looks at how using a tablet in the evening affects children's sleep, mood, and thinking skills. Researchers want to separate the effects of the screen's light from the effects of exciting content. About 220 children ages 8 to 11 will take part, wearing a watch to track…

This study looks at how different diets—a typical Western diet versus a healthier, fiber-rich one—impact sleep quality, heart rate, and metabolism. Researchers will monitor 24 healthy adults aged 18-32 using wearable devices and sleep tests. The goal is to understand how food cho…

This study looks at how difficult childhood experiences and sleep problems might harm blood vessels in young adults aged 18-29. Researchers will measure sleep quality and blood vessel function, and test whether a 6-week sleep therapy program can improve vessel health. The goal is…

This study looks at how different light patterns and meal timing affect your body's ability to process food when you're not sleeping enough. Researchers will track 120 healthy adults aged 18-35 over 4-6 months with overnight stays and tests. The goal is to understand how these li…

This study looks at how sleep helps clean the brain. Researchers will use special MRI scans to see the brain's waste-clearing system in 16 healthy young adults. They will also test a headband that tracks brain waves and uses mild electrical pulses to improve sleep and brain funct…

This study looks at how a full day without sleep changes certain proteins in the blood that are linked to Alzheimer's disease. Researchers want to see if these changes differ based on a person's APOE gene type, which is known to affect Alzheimer's risk. The study involves 60 heal…

This study looks at how sleep and body clocks affect the brains of teenagers and their risk for using substances like alcohol or drugs. Researchers will monitor the sleep patterns and brain activity of 200 healthy teens aged 13-18. The goal is to understand how changes in sleep a…

This study tests a new computer program that reads brain activity to tell if a person is conscious or not. Thirty healthy adults will have their brains stimulated with magnetic pulses while they are awake and asleep. The goal is to see if the program can accurately detect conscio…

This study tests whether morning bright light therapy can improve sleep in 300 veterans with traumatic brain injury. Researchers will measure changes in inflammation, energy production in cells, and brain cleaning systems. The goal is to understand how better sleep might support …

This study looks at how sleep, physical activity, and daily rhythms are linked to ADHD symptoms in children. Researchers will use a wristband to track activity and sleep for two weeks, and also do brain scans and thinking tests. The goal is to better understand ADHD, not to test …

This study looks at how severe sleep deprivation in the first 48 hours after childbirth affects a mother's motivation to breastfeed and how successful breastfeeding is. Researchers will follow 167 new mothers, including those who had C-sections, and measure their sleep quality, b…

This study looks at how not getting enough sleep or having insomnia changes the way people handle their emotions. Researchers will compare three groups: people who sleep only 4 hours for three nights, people with insomnia, and healthy sleepers. Participants will do emotion tasks …

This study looks at how sleep problems impact thinking skills and quality of life in people treated for breast cancer. Researchers will track sleep patterns and mental function in 75 patients aged 39 to 69. The goal is to better understand these links and find ways to improve sle…

This study is adapting a sleep screening questionnaire for Turkish children and teens with complex chronic conditions (like multiple health problems). Researchers will test if the tool is accurate and reliable, and will also look at how common sleep issues are in these children. …

This study follows 50 people over age 50 who had arthroscopic rotator cuff repair. Researchers will measure shoulder disability, pain levels, and sleep quality during recovery. The goal is to better understand typical recovery patterns and help create clearer rehab guidelines.

This study tests a new program called Bedtime Stories that sends personalized sleep tips to caregivers' phones. Researchers want to see if it helps improve sleep habits in children from low-income families. About 75 caregivers of kids aged 5-11 will take part. The goal is to see …

This study looks at how sleep changes affect the bacteria in your gut. Researchers will ask people who sleep too little to sleep more, and people who sleep enough to sleep less, for 14 days. They want to see if these sleep changes alter the types and amounts of gut bacteria. The …

This study aims to learn more about psychiatric, behavioral, and developmental disorders that begin in childhood. Researchers will observe up to 1,000 people of any age who have these conditions, along with their family members. The goal is to better understand how these disorder…

This study looks at how the COVID-19 pandemic may have changed people's physical activity, sleep, blood pressure, and mental stress. Researchers at Indiana University will track 100 adults aged 18-75 using wearable devices, fitness tests, and blood samples. The goal is to underst…

This study looks at whether experiencing a one-hour time delay every day can shift your body's internal clock. Researchers will measure melatonin levels and reaction times in 40 healthy couples who live together. The goal is to understand how our daily routines affect sleep and c…

This study looks at whether giving sleep tips to expecting parents can help their babies sleep longer and have fewer sleep problems. About 391 families will take part, with some getting regular sleep advice by email and others not. Researchers will track the babies' sleep for up …

This study looks at how a commercially available ketone drink (Ketone-IQ) affects sleep and breathing in 20 healthy adults aged 18-50. Participants take two different doses at home on separate nights and measure their ketone levels and sleep quality using a headband device. The g…

This study looks at whether aerobic exercise (stationary biking) and daytime naps can boost motor skill learning and brain function in 20 adults with relapsing-remitting multiple sclerosis. Participants will do hand coordination tests while their brain and muscle activity are mea…

This study looks at how daily light patterns relate to migraine headaches and sleep quality in adults. Over 8 weeks, 20 participants will track their migraines, light exposure, and sleep using diaries and devices. The goal is to understand these connections, not to test a new tre…

This study looks at how sleep and the body's internal clock influence blood pressure in people with high blood pressure. Researchers will monitor 32 adults aged 25-64 to understand why some have a 'non-dipping' pattern where blood pressure stays high at night. The goal is to unco…

This study looks at how getting less sleep than usual affects blood pressure in healthy adults. Researchers will compare people of normal weight and those with obesity, aged 18 to 45. Participants will have their sleep shortened and their blood pressure measured to see if there i…

This study looks at whether giving nutrition during the day instead of at night can help heart surgery patients in the ICU sleep better and keep their body clocks on track. Researchers will monitor sleep patterns and body rhythms in 30 adults. The goal is to find simple ways to i…

This study follows 1000 Canadian adults who are authorized to use medical cannabis for pain, sleep issues, anxiety, depression, or epilepsy. Researchers will track changes in symptoms using standard questionnaires over 24 weeks. The goal is to gather real-world evidence on how we…

This study aims to improve how sleep is measured for nightshift workers, whose inverted schedules make standard sleep trackers inaccurate. Researchers will use an Apple Watch along with machine learning to better detect daytime sleep. About 100 nightshift workers will participate…

This study looks at how sleep and physical activity change for blood cancer patients and their caregivers after a stem cell transplant. Researchers will ask 66 patient-caregiver pairs to fill out questionnaires about sleep, mood, fatigue, and quality of life. The goal is to under…

This study tests whether a home-based mobile app can help 3-4 year olds who currently meet few or no daily movement, sleep, and screen-time guidelines. About 80 children will wear activity trackers, and parents will use the app for weekly lessons and goals. The goal is to see if …

This study looks at sleep patterns in 20 teenagers aged 15-17 who have had pain for more than 3 months. Researchers will test a simple relaxation technique before bed to see if it helps improve sleep quality and how the brain processes emotional memories. Participants sleep at ho…

This study looks at how quickly losing water weight affects combat athletes' sleep, thinking skills, and muscle strength. Researchers will monitor 12 athletes before and after rapid weight loss using sleep trackers, strength tests, and thinking quizzes. The goal is to understand …