Centre Hospitalier Universitaire De Nīmes
Clinical trials sponsored by Centre Hospitalier Universitaire De Nīmes, explained in plain language.
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Vitamin d boost may help obese Teens' arteries
Disease control CompletedThis study looked at whether adding vitamin D supplements to a healthy diet and exercise program could improve blood vessel function in obese teenagers. 49 teens participated over 3 months. The main goal was to see if the vitamin helped the arteries relax and work better, which i…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 26, 2026 04:00 UTC
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Dialysis breakthrough: safer blood thinner found for Bleeding-Risk patients
Disease control CompletedThis study tested two ways to prevent blood clots during dialysis in 60 patients at high risk of bleeding. One method uses a special filter (citrate) that only works in the dialysis machine, while the other uses a low dose of a standard blood thinner (heparin) throughout the body…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 26, 2026 03:56 UTC
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Home pharmacy Check-Ins may cut COPD attacks
Disease control CompletedThis study looked at whether having a pharmacist talk with patients at home after a hospital stay could reduce flare-ups of chronic obstructive pulmonary disease (COPD). 174 adults with moderate to severe COPD took part. The main goal was to count how many times patients had wors…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 26, 2026 03:54 UTC
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Could a Low-Dose immune booster tame ALS?
Disease control CompletedThis study tested whether a low dose of interleukin-2 (IL-2), a protein that helps regulate the immune system, is safe and can increase regulatory T cells in people with amyotrophic lateral sclerosis (ALS). 36 adults with ALS received either IL-2 or a placebo for five days. The m…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 26, 2026 03:53 UTC
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Smart software aims to perfect antibiotic dosing in septic shock
Disease control CompletedThis study tested whether a computer program (BestDose) could help doctors give the right amount of the antibiotic amikacin to patients with septic shock. The goal was to see if more patients would reach the ideal drug level in their blood after the second dose. 180 critically il…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 26, 2026 03:53 UTC
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Could a tiny embolization keep prostate cancer in check?
Disease control CompletedThis small pilot study tested whether blocking the blood supply to one side of the prostate (prostatic arterial embolization) can control low-risk prostate cancer in men who are already on active surveillance. Ten men with unilateral, low-volume tumors participated. The main goal…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 26, 2026 03:51 UTC
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New hope for endometriosis patients: fertility preservation without compromise
Disease control CompletedThis study looked at 130 women with endometriosis who had their eggs frozen to preserve fertility. It compared a newer method using the drug dienogest against standard treatments to see if it could collect a similar number of mature eggs. The goal is to offer a safe and effective…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 26, 2026 03:51 UTC
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Mesh surgery for prolapse: does it hold up?
Disease control CompletedThis study tested a special mesh (Uphold LITE) to repair uterine prolapse, a condition where the uterus drops into the vagina. 121 women received the mesh and were followed for 12 months. The goal was to see if the mesh corrected the prolapse, relieved symptoms like bulging, and …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 22, 2026 14:05 UTC
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Mesh vs. no mesh: which bladder prolapse surgery holds up better over time?
Disease control CompletedThis study looked at 75 women who had surgery for bladder prolapse (a condition where the bladder bulges into the vagina). It compared two techniques: one using a special mesh (UGYTEX®) and one without mesh. The goal was to see which approach worked better over 5 to 8 years after…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 22, 2026 14:05 UTC
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Longer ad pause after gambling Self-Ban may cut relapse
Disease control CompletedThis study looked at whether extending the time gambling websites stop sending ads after a person voluntarily bans themselves helps reduce gambling. Over 2,500 adults who self-excluded from online sports betting, poker, or horse racing were randomly assigned to either the usual p…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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Does a hormone shot improve pregnancy success with frozen embryos?
Disease control CompletedThis study looked at whether letting women ovulate naturally or using a hormone shot (HCG) leads to more pregnancies when transferring frozen embryos. 103 women aged 18-40 with regular cycles took part. The goal was to see if one method gives a better chance of getting pregnant.
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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Could a tiny dose of IL-2 slow ALS? new trial results are in
Disease control CompletedThis study tested a low-dose immune treatment (IL-2) in 304 people newly diagnosed with ALS, a serious nerve disease. The goal was to see if boosting certain immune cells could slow the disease and help people live longer. Participants received either the drug or a placebo for 18…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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Seaweed mineral combo tested for aging arteries
Disease control CompletedThis study tested whether taking a spirulina-silicon supplement could improve artery health in healthy older adults. Researchers measured how well blood vessels relaxed and how stiff the arteries were. The goal was to see if this supplement could help control age-related changes …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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Daily ultrasound could keep heart failure patients out of the hospital
Disease control CompletedThis study tested whether doing a simple ultrasound at the bedside every day helps doctors better manage fluid levels in patients hospitalized for acute heart failure. The goal was to see if this approach leads to fewer patients being readmitted to the hospital within 30 days. Th…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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Which filter cleans blood better? study tests two dialysis methods for ICU patients
Disease control CompletedThis study looked at 163 intensive care patients with sudden kidney failure to compare two blood-filtering techniques: hemodiafiltration and hemofiltration. The main goal was to see which method better reduces waste products like urea in the blood after 12 hours. Results help doc…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New french test could spot delirium in seniors faster
Diagnosis CompletedThis study tested a French version of the Confusion Assessment Method (CAM), a tool to quickly diagnose sudden confusion (delirium) in elderly patients. Researchers compared the CAM results with a psychiatrist's diagnosis using standard criteria. The goal was to see how accurate …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 26, 2026 03:58 UTC
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Grinding up samples could improve infection detection in bones and joints
Diagnosis CompletedThis study tested whether grinding up tissue samples (using a device called Ultra Turrax) helps doctors find bacteria in bone and joint infections better than the usual lab method. Researchers looked at samples from 122 people suspected of having an infection around implants like…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 26, 2026 03:57 UTC
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PET scan breakthrough: better brain lesion diagnosis?
Diagnosis CompletedThis study looked at whether a type of PET scan (18F-DOPA-PET) can help doctors tell the difference between brain tumors and non-cancerous brain lesions. Researchers analyzed scans from 74 patients with suspected brain tumors. The goal was to find the best way to use this scan to…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 26, 2026 03:56 UTC
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Which test spots brain fog better? study pits MoCA vs BEARNI
Diagnosis CompletedThis study looked at two simple tests (MoCA and BEARNI) to see which one is better at finding thinking and memory problems in people with alcohol use disorder. Researchers tested 90 patients and compared the results to a full set of detailed brain tests. The goal was to find out …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 26, 2026 03:56 UTC
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Simple blood test after thyroid surgery may spare patients unnecessary worry
Diagnosis CompletedThis study looked at 300 patients who had their thyroid gland removed. Doctors wanted to see if measuring parathyroid hormone (PTH) right after surgery could reliably rule out hypoparathyroidism, a condition where calcium levels drop too low. The goal was to find a PTH cutoff val…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 26, 2026 03:54 UTC
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Blood test may predict kidney danger in muscle injury patients
Diagnosis CompletedThis study looked at 197 emergency room patients with rhabdomyolysis (severe muscle breakdown) to see if a blood test for a protein called NGAL could predict who would develop acute kidney failure within 48 hours. The goal is to help doctors identify high-risk patients earlier an…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 20, 2026 11:53 UTC
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New scanner sees fractures with far less radiation
Diagnosis CompletedThis study compared a new ultra low-dose CT scanner to standard X-rays for finding broken bones in the back, pelvis, arms, and legs. 554 emergency room patients with suspected fractures were scanned with both methods. The goal was to see if the low-dose scanner could detect fract…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 18, 2026 12:07 UTC
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Ultrasound shows promise for spotting rare nerve disease
Diagnosis CompletedThis study looked at whether a simple, painless ultrasound can help doctors diagnose CANVAS, a rare genetic disorder that causes balance problems, nerve damage, and dizziness. Researchers measured the size of nerves in 35 adults with CANVAS and compared them to healthy people. Th…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 18, 2026 12:01 UTC
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Blood test may spot dangerous headaches in the ER
Diagnosis CompletedThis study looked at whether measuring a protein called S100B in the blood can help emergency doctors tell the difference between common headaches (like migraines) and headaches caused by a more serious problem (like bleeding or infection). 81 adults with bad headaches but no rec…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated May 14, 2026 12:05 UTC
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Mesh may stop hernias after colostomy surgery
Prevention CompletedThis study tested whether placing a special mesh during colostomy surgery can prevent hernias from forming around the stoma. 200 adults having their first colostomy took part. Half got the mesh, half did not, and doctors checked for hernias every 3 months for 2 years.
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Prevention
Last updated May 26, 2026 04:00 UTC
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Cranberry capsules tested to stop catheter infections after surgery
Prevention CompletedThis study tested whether cranberry gel capsules can prevent E. coli infections in patients who have a urinary catheter placed during pelvic surgery. About 270 adults took part. The idea is that cranberry compounds may stop bacteria from sticking to the catheter, reducing infecti…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Prevention
Last updated May 26, 2026 03:59 UTC
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Pharmacist check boosts lifesaving vaccine rates in hospital patients
Prevention CompletedThis study tested whether a pharmacist reviewing medications at hospital admission could increase pneumococcal vaccination in patients at high risk for serious infections. Over 600 adults with chronic illnesses or weakened immune systems took part. The goal was to raise vaccinati…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Prevention
Last updated May 26, 2026 03:50 UTC
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Teamwork stops drug errors before surgery
Prevention CompletedThis study tested whether having a pharmacist and anesthesiologist work together during the pre-surgery checkup can prevent mistakes with patients' regular medications. 378 adults scheduled for surgery took part. The goal was to see if this teamwork reduces errors and improves sa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Prevention
Last updated May 20, 2026 11:54 UTC
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Heart rate shield: new drug combo may protect fragile patients during emergency intubation
Symptom relief CompletedThis study looked at whether giving remifentanil, a fast-acting painkiller, during emergency breathing tube placement can prevent a dangerously fast heart rate. 75 fragile patients who needed rapid intubation were given one of two doses of remifentanil. The goal was to see if it …
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 04:04 UTC
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New anesthesia combo may ease pain after hand surgery
Symptom relief CompletedThis study tested two ways to numb the hand, wrist, or elbow for surgery. One used lidocaine alone, the other added a longer-lasting drug called ropivacaine. The goal was to see if the combination reduces pain and improves the patient's experience after going home. 91 adults took…
Phase: PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 04:03 UTC
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New device helps stroke patients regain hand grasp
Symptom relief CompletedThis study tested a hand grasp neuroprosthesis that uses electrical stimulation to help stroke survivors open their hand and grasp objects. Eleven people with chronic stroke-related hand paralysis participated. The device improved their ability to pick up and move a glass or spoo…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 04:03 UTC
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Nerve block injection slashes Post-Surgery painkiller use
Symptom relief CompletedThis study tested whether a nerve block injection (erector spinae block) can reduce pain and the need for morphine after lumbar spine surgery. Fifty adults having lower back surgery received either the nerve block or a placebo. The goal was to see if the block provides better pai…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 04:03 UTC
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Heart attack recovery gets a buddy system: patient partners boost exercise
Symptom relief CompletedThis study tested whether having a 'patient partner' (a fellow heart attack survivor) alongside a healthcare professional helps people stay physically active after cardiac rehab. 84 adults who had a heart attack and completed phase 2 rehab were split into two groups. One group go…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 03:59 UTC
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Which breathing tube causes the least sore throat? study compares three devices
Symptom relief CompletedThis study tested three different breathing devices used during short surgeries to see which one causes the least sore throat afterward. Over 500 adults took part, and researchers measured pain, how easy the device was to place, and how many tries it took. The goal was to find a …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 03:57 UTC
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Could a simple drug combo cut morphine use after colon surgery?
Symptom relief CompletedThis study looked at whether adding the drug nefopam to standard pain relief (morphine and paracetamol) can reduce the amount of morphine needed after major colon surgery. 80 adults having planned surgery for colon cancer or diverticulosis took part. The main goal was to measure …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 03:57 UTC
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Robot or not? new study compares surgery methods for pelvic organ prolapse
Symptom relief CompletedThis study looked at 365 women with pelvic organ prolapse to compare two types of minimally invasive surgery: robot-assisted and standard laparoscopic. The main goal was to see which method had fewer complications within 30 days after surgery. Researchers also checked recovery ti…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 03:56 UTC
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Virtual reality mirror trick may ease chronic arm pain
Symptom relief CompletedThis study tested a new treatment called augmented reality mirror therapy for people with complex regional pain syndrome (CRPS) in the arm or hand. Seven participants used a virtual reality system that showed a mirror image of their healthy arm, making their brain think the painf…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 03:56 UTC
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One-Side or both? new study tests best way to free men from catheters
Symptom relief CompletedThis study looked at 50 elderly men (over 70) with an enlarged prostate who needed a long-term urinary catheter because surgery wasn't an option. Doctors compared blocking the blood supply to one side of the prostate versus both sides, hoping to remove the catheter. The goal was …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 03:55 UTC
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Hypnosis or laughing gas? study tests pain relief for kids getting stitches
Symptom relief CompletedThis study tested two ways to manage pain in children getting stitches in the emergency room. One group received a gas mixture called MEOPA, and the other group received hypnosis with the option of MEOPA if needed. The goal was to see which approach better controlled pain during …
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 03:55 UTC
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Mind games boost heart rehab workouts
Symptom relief CompletedThis study tested whether a simple mental exercise called evaluative conditioning could help people who had a heart attack exercise more intensely during cardiac rehab. Twenty-four patients were split into two groups: one received exercise-friendly conditioning, the other diet-re…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 03:51 UTC
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Could HIV drugs clear psoriasis? tiny trial hints at new approach
Symptom relief CompletedThis study tested whether drugs that block reverse transcriptase (an enzyme) could help treat psoriasis. The idea was that these drugs might reduce inflammation caused by extra DNA inside skin cells. Only 8 people with plaque psoriasis took part, and the main goal was to see chan…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 03:51 UTC
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Laughing gas eases frozen shoulder therapy pain, study finds
Symptom relief CompletedThis study tested whether breathing a mix of oxygen and nitrous oxide (laughing gas) during physical therapy helps people with frozen shoulder move better and feel less pain. 75 adults with frozen shoulder took part. The goal was to see if the gas improves shoulder function and r…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 03:51 UTC
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Wisdom tooth pain relief: new study tests ropivacaine
Symptom relief CompletedThis study looked at whether a numbing medicine called ropivacaine can reduce pain in the first 24 hours after having all four wisdom teeth removed under general anesthesia. 100 adults participated, and their pain was measured at several time points. The goal was to see if ropiva…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 03:51 UTC
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Nerve zap showdown: one side or two for bladder relief?
Symptom relief CompletedThis study tested whether stimulating nerves on one or both sides of the body works better for people with overactive bladder that hasn't improved with standard treatments. 55 adults took part, and the main goal was to see if one method led to at least a 50% improvement in sympto…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 26, 2026 03:50 UTC
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New injection technique may offer better knee pain relief
Symptom relief CompletedThis study tested a new way to inject medicine into the knee for people with degenerative meniscus tears (a common cause of knee pain). The researchers compared injecting directly into the meniscus wall versus the standard injection into the joint space. 70 adults with knee osteo…
Phase: PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 20, 2026 11:55 UTC
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Wheelchair that adapts to spasms could improve comfort for patients
Symptom relief CompletedThis study tested a special wheelchair (NETTI) that can move with a person's involuntary muscle spasms, comparing it to a regular locked mode. Four people who have frequent spasms and use a wheelchair took part. Researchers measured how much they slipped forward and the force on …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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New light probe offers hope for menopausal vaginal discomfort
Symptom relief CompletedThis study tested a new vaginal probe that uses special lights (photobiomodulation) to help postmenopausal women with vaginal atrophy that hasn't improved with other treatments. The probe aims to reduce pain and discomfort by stimulating natural tissue repair. The study included …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 19, 2026 11:59 UTC
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New study finds best pain cocktail for shoulder surgery recovery
Symptom relief CompletedThis study looked at whether adding tramadol, nefopam, or an opioid to standard painkillers (paracetamol and ketoprofene) helps adults recover better after shoulder surgery. 92 adults who had shoulder surgery under general anesthesia with a nerve block took part. The goal was to …
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 19, 2026 11:46 UTC
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Ketamine shows promise for rapid relief of suicidal ideation
Symptom relief CompletedThis study tested whether ketamine, given as two infusions, can quickly reduce suicidal thoughts in 156 patients hospitalized for suicide risk. The main goal was to see if suicidal ideas resolved within 24 hours after the second dose. The approach aims to provide fast, short-term…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 18, 2026 12:08 UTC
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Can a simple injection ease menopause pain? new study says maybe
Symptom relief CompletedThis small study tested whether injecting a gel-like substance (hyaluronic acid) into the vaginal area could help menopausal women with pain during sex. Twenty women received the injections and were followed for 8 weeks. The main goal was to see if the vaginal lining thickened, w…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 13, 2026 16:01 UTC
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New painkiller may cut side effects after hip surgery
Symptom relief CompletedThis study tested if a painkiller called oxycodone causes fewer side effects than morphine after hip replacement surgery. 246 adults were given one of the two drugs to control pain right after their operation. The goal was to see if oxycodone could reduce problems like nausea, vo…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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Can your first week of pain after surgery predict chronic pain?
Knowledge-focused CompletedThis study followed 392 adults who had planned surgeries to map their pain levels over the first 7 days after the operation. Researchers wanted to see if different pain patterns could help predict who might develop long-term chronic pain 3 months later. The goal is to better unde…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:05 UTC
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Can rehab rewire the drive to move? new study explores motivation in chronic back pain
Knowledge-focused CompletedThis study looked at 89 adults with chronic low back pain who joined a rehabilitation program. Researchers measured changes in physical activity and sitting time, and also explored what motivates patients to be active. The goal was to understand how rehab affects both behavior an…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:04 UTC
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New therapies for Women's pelvic pain under the microscope
Knowledge-focused CompletedThis study observed 173 women with pelvic or perineal issues (like pain, incontinence, or scarring) who didn't get enough help from standard treatments. Researchers tracked the use of newer therapies such as LED light, radiofrequency, laser, and hyaluronic acid injections to unde…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:04 UTC
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Blood markers may forecast pregnancy risks in autoimmune disorder
Knowledge-focused CompletedThis study looked at 513 women with antiphospholipid syndrome (APS) starting a new pregnancy. Researchers measured two blood markers (PGF and sFlt1) before and after the first dose of a standard blood thinner. The goal was to see if changes in these markers could predict serious …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:04 UTC
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Throat bone may play role in stroke risk, new study suggests
Knowledge-focused CompletedThis study examined CT scans from 206 patients who had carotid artery surgery to see if the hyoid bone (a small bone in the neck) is positioned differently in people with narrowed arteries. Researchers measured the distance and angle between the hyoid bone and carotid artery, and…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:04 UTC
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Anesthesia training study aims to cut surgery risks
Knowledge-focused CompletedThis study looked at whether training healthcare teams to use special monitoring tools during general anesthesia can reduce serious problems like heart attacks, strokes, or death within 28 days after surgery. Over 1,000 adults having intermediate- or major-risk non-cardiac surger…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:03 UTC
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Smart angel device tested to keep surgery patients safe at home
Knowledge-focused CompletedThis study tested whether a device called SMART ANGEL, which monitors heart rate, blood pressure, oxygen levels, and symptoms like pain and nausea, could help people recover better at home after major or intermediate outpatient surgery. Over 1,200 adults took part. The goal was t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:03 UTC
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Major study reveals gaps in care for rare diabetic foot condition
Knowledge-focused CompletedThis study examined how doctors in France and Belgium diagnose and treat Charcot foot, a rare but serious complication of diabetes that can lead to foot ulcers and amputation. Researchers collected information from over 1,100 patients to understand current practices and identify …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:03 UTC
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Nerve block study reveals metabolic disease impact on recovery
Knowledge-focused CompletedThis study looked at 120 people having hand or wrist surgery to see if kidney failure or diabetes affects how long a nerve block lasts. Researchers measured the time it took for feeling to return after the block. The goal was to understand how these metabolic conditions change th…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:03 UTC
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Healthy lung ultrasound study aims to set new standards
Knowledge-focused CompletedThis study involved 30 healthy volunteers aged 18-50 to measure normal lung ultrasound values, called pleural strain. Researchers used a technique called speckle tracking to see how the lungs move during breathing and with a breathing mask. The goal was to establish baseline numb…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:02 UTC
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Mind over matter: picturing success improves IV skills in med students
Knowledge-focused CompletedThis study looked at whether a mental imagery session—picturing the steps in your mind—could help 5th-year medical students place a peripheral IV catheter on a training mannequin. 96 students took part. The goal was to see if this technique improves first-attempt success and redu…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:02 UTC
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New device helps doctors hit the vein on first try
Knowledge-focused CompletedThis study tested a new needle-steering device to help doctors place central lines (large IVs) in the chest. Researchers compared the device to standard ultrasound guidance using a mannequin. The device helped doctors succeed on the first try more often and with fewer needle stic…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:02 UTC
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Can a machine match doctors in measuring heart function during emergencies?
Knowledge-focused CompletedThis study looked at 70 ICU patients with acute circulatory failure (dangerously low blood pressure) to see if an automatic ultrasound measurement of heart blood flow works as well as the traditional manual method. The goal was to check how closely the two methods agree. This is …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:01 UTC
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Gut leak study in septic shock: no treatment, just facts
Knowledge-focused CompletedThis study looked at 60 adults with septic shock in the ICU to see how often bacteria leak from the gut into the blood. Researchers measured specific markers in blood samples taken over the first week. The goal was to understand this process better, not to test a new treatment.
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:01 UTC
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Scientists track bacteria shifts after Women's surgery
Knowledge-focused CompletedThis study looked at how the bacteria in the vagina, urine, and gut change before and after vaginal surgery in 60 menopausal women. Researchers took swabs before surgery and at 6 weeks and 12 months after to see if different bacteria types are linked to symptoms. The goal was to …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 04:01 UTC
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Hidden danger: abuse may raise blood clot risk for women on the pill
Knowledge-focused CompletedThis study looked at whether intimate partner violence (IPV) is a risk factor for venous thromboembolism (VTE) in women taking combined oral contraceptives. Researchers compared 997 women who had a first blood clot with matched women who did not, using a questionnaire to measure …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:59 UTC
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MRI reveals brain differences in violent suicide attempts
Knowledge-focused CompletedThis study used MRI scans and computer tasks to compare decision-making and brain activity in 40 people who had attempted suicide (some using violent methods) against those who had not. Researchers looked for differences in brain structure, function, and how people learn from rew…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:59 UTC
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Vitamin D's hidden power: new study reveals immune cell changes in healthy adults
Knowledge-focused CompletedThis study looked at how taking high doses of vitamin D for 3 months changes immune cells in healthy adults. Researchers measured different types of immune cells in the blood to see if vitamin D has an effect. The goal was to better understand how vitamin D might help with diseas…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:59 UTC
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Smartphone checkups could cut chemo waste, study finds
Knowledge-focused CompletedThis study tested whether asking patients with digestive cancer to report their symptoms online could give doctors enough information to decide if chemotherapy should be prepared, instead of requiring an in-person exam. 138 patients participated. The goal was to reduce the number…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:59 UTC
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MRI study sheds light on mysterious brain iron deposits
Knowledge-focused CompletedThis study looked at 111 people with cerebral amyloid angiopathy (CAA), a condition where proteins build up in brain blood vessels. Researchers used MRI scans to see if iron deposits in the cerebellum are caused by local bleeding or spread from other areas. The goal was to better…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:58 UTC
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ER ultrasound may predict ventilator need in breathing emergencies
Knowledge-focused CompletedThis study looked at 104 adults in the emergency room with severe breathing problems. Doctors used an ultrasound to measure how far the diaphragm (the main breathing muscle) moved. The goal was to see if this measurement could predict which patients would need a breathing machine…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:58 UTC
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Surgery for vaginal laxity: new look at sexual outcomes
Knowledge-focused CompletedThis study looked back at 55 women who had surgery to tighten the vaginal opening (perineal repair) to treat vaginal laxity. The goal was to see how the surgery affected their sexual health and any discomfort. Researchers used a special questionnaire to measure results. This was …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:58 UTC
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Antibiotic levels tracked in lung fluid of sickest pneumonia patients
Knowledge-focused CompletedThis study looked at how the antibiotic ceftobiprole spreads in the blood and lungs of 12 adults with severe pneumonia who needed a breathing machine. Researchers gave a high dose continuously for 24 hours and took blood and lung fluid samples to measure drug levels. The goal was…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:58 UTC
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Tiny brain lesions may reveal hidden heart risk in young stroke survivors
Knowledge-focused CompletedThis study looked at 50 young adults (under 60) who had a stroke with no clear cause. Researchers compared those with a small heart defect called PFO to those without it. They found that small strokes in the outer part of the cerebellum were more common in patients with PFO. This…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:57 UTC
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Breathing tube removal method may affect oxygen levels after surgery
Knowledge-focused CompletedThis study looked at 68 adults undergoing arm or leg surgery with general anesthesia. Researchers compared two ways of removing the breathing tube: one using positive pressure and one using suction. The goal was to see which method helped patients breathe on their own longer with…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:57 UTC
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Thirst-Guided hydration may prevent salt imbalance in extreme runners
Knowledge-focused CompletedThis study followed 198 runners in the 2015 Ultra-Trail Mont-Blanc to see if drinking only when thirsty (versus following a set schedule) helps maintain healthy sodium levels in the blood. Researchers measured sodium before and after the race, along with weight changes and runnin…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:57 UTC
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Heart map may predict AFib return after ablation
Knowledge-focused CompletedThis study tested whether a special heart map (isochron map) can predict if atrial fibrillation will return after a standard treatment called radiofrequency ablation. Researchers followed 175 adults for 18 months to see who had a relapse. The goal was to find better ways to forec…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:56 UTC
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ER imaging guidelines put to the test: do they cut unnecessary scans?
Knowledge-focused CompletedThis study looked at whether giving emergency room doctors guidelines for ordering imaging tests (like X-rays or CT scans) helps them choose more relevant exams. Over 8,500 patients were included, and researchers compared how often the initial suspected diagnosis was confirmed by…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:56 UTC
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17-Year study links pregnancy loss condition to cancer risk
Knowledge-focused CompletedThis study followed 1,592 women who had pregnancy losses (three early miscarriages or one fetal death) to see if those with antiphospholipid syndrome (APS) develop cancer more often. Researchers compared women with APS, those with other clotting disorders, and those without any c…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:56 UTC
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Scientists probe colon Cancer's toughest cells
Knowledge-focused CompletedThis study aimed to identify and understand special cells in colon cancer that may help the cancer spread and resist chemotherapy. Researchers collected samples from 60 patients' tumors, blood, and metastases to study these cells in the lab. The goal was to learn more about how t…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:55 UTC
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Scientists hunt for biological clues in mysterious movement disorder
Knowledge-focused CompletedThis study looked at 20 adults having their first episode of conversion disorder, a condition where psychological stress causes physical symptoms like paralysis or abnormal movements. Researchers measured inflammation markers in the blood and compared them to brain scans to find …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:55 UTC
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Spinal fluid clues may reveal who will develop MS
Knowledge-focused CompletedThis study looked at 100 people who have brain scan abnormalities but no MS symptoms (radiologically isolated syndrome). Researchers measured four substances in their spinal fluid and blood to see if any could predict who later develops multiple sclerosis. The goal was to find be…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:55 UTC
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Ultrasound-Guided catheter study aims to improve safety and success
Knowledge-focused CompletedThis study tested two different spots (lower neck vs. collarbone area) for placing a central line using ultrasound guidance. 210 adults who needed a central line were randomly assigned to one of the two methods. The goal was to see which technique works better and to plan a large…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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Video chat with anesthesiologist just as safe as In-Person visit?
Knowledge-focused CompletedThis study looked at whether a video call with an anesthesiologist before surgery works as well as an in-person visit. 172 adults scheduled for surgery at a French hospital took part. Researchers checked if both methods were equally good at gathering medical info, assessing surgi…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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ICU antibiotic study: are patients getting enough?
Knowledge-focused CompletedThis study looked at 98 critically ill patients in intensive care to check if the antibiotics they received reached high enough levels in their blood to kill bacteria effectively. Researchers measured specific antibiotics (beta-lactams and glycopeptides) and compared them to targ…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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Blood clues: could a simple test spot cancer spread from polyps?
Knowledge-focused CompletedThis study explored whether people with intestinal polyps have cancer cells or specific proteins in their blood that could signal early tumor spread. Researchers compared blood samples from 120 patients undergoing colonoscopy—some with polyps, some without. The goal was to find n…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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New tool aims to predict kidney recovery after severe injury
Knowledge-focused CompletedThis study aimed to create a tool that helps doctors decide which patients with severe acute kidney injury (AKI) would benefit from seeing a kidney specialist (nephrologist) after leaving the hospital. Researchers looked at 319 patients who needed dialysis for severe AKI to find …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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New education program aims to help men with advanced prostate cancer understand their treatment
Knowledge-focused CompletedThis study tested a new education program for 18 men with metastatic prostate cancer who were taking next-generation hormone therapy. The program was designed to help them better understand their disease, stick to their medication, and improve their quality of life. Researchers c…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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Can a new CT method give clearer bone images with less radiation?
Knowledge-focused CompletedThis study tested whether a newer CT reconstruction method (ASIR) can produce bone SPECT images as clear as the standard method (FBP) while using even less radiation. 75 adults scheduled for a SPECT-CT exam took part. The goal was to see if image quality could be maintained with …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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Blood test showdown: which method spots melanoma cells better?
Knowledge-focused CompletedThis study compared two blood test methods (EPISPOT and CellSearch) to see how well they find circulating melanoma cells in people with advanced melanoma. Researchers took blood samples from 73 participants, including patients with stage 4 melanoma and hospitalized volunteers wit…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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Hospital pharmacist study aims to cut errors and save money
Knowledge-focused CompletedThis study tested whether having a clinical pharmacist on the hospital team improves the quality and lowers the cost of treatment for patients in infectious disease and internal medicine units. Researchers tracked 500 patients to see if the pharmacist helped reduce medication err…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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Brain scans reveal how stroke survivors recover movement
Knowledge-focused CompletedThis study used a special light-based brain scanner (fNIRS) to watch how the brain rewires itself in the first two months after a stroke. Ten stroke survivors were followed from day 0 to day 60 to see how their brain activity changed as they regained movement. The goal was to cre…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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French ICU study tracks COVID-19 care in over 1,000 patients
Knowledge-focused CompletedThis study looked at over 1,000 adults with COVID-19 who were admitted to intensive care units (ICUs) in France. Researchers collected information on how these patients were treated and what complications they had. The goal was to better understand what factors affect their recov…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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Immune cells linked to insulin problems in new study
Knowledge-focused CompletedThis study looked at how certain immune cells (called peripheral blood mononuclear cells) might affect the body's response to insulin. Researchers took blood samples from 30 healthy volunteers and tested whether substances released by these cells could block insulin signals in li…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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Vaccine side effect mystery: scientists check immune cell changes
Knowledge-focused CompletedThis study looked at how mRNA COVID-19 vaccines change the activity of certain immune cells (monocytes) in people of different ages. Researchers measured oxygen-related molecules produced by these cells before and after vaccination. The goal was to understand the body's response …
Phase: EARLY_PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC
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Gene hunt: why some kidney cancer patients get more drug
Knowledge-focused CompletedThis study looked at 43 people with kidney cancer who were starting treatment with the drug sunitinib. Researchers measured how much of the drug stayed in their blood and checked their genes to see if certain genetic differences explained why drug levels vary from person to perso…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:53 UTC
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Ultrasound-Guided nerve tests may reduce pain
Knowledge-focused CompletedThis study tested whether using ultrasound to find the best spot for nerve stimulation during electroneuromyography (ENMG) could lower the electrical intensity needed, making the test more comfortable. 290 adults aged 18-80 who needed an ENMG took part. The results will show if t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:53 UTC
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Timing is everything: fluid response in septic shock may change in minutes
Knowledge-focused CompletedThis study looked at 145 people with septic shock to see if the timing of checking fluid effectiveness changes results. Patients received 500 ml of fluid over 10 minutes, and doctors checked if they responded right away and again 20 minutes later. The goal was to see how many pat…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:53 UTC
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Twin birth study: vaginal vs. C-Section and incontinence risk
Knowledge-focused CompletedThis study looked at over 3,000 first-time mothers of twins to see if the way they gave birth (vaginal or cesarean) affected their risk of leaking urine 3 months after delivery. The goal was to understand which delivery method might be safer for bladder health. Results help guide…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:53 UTC
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Back pain study reveals hidden instability in everyday movements
Knowledge-focused CompletedThis study looked at how chronic low back pain changes the way people move. Researchers compared 70 participants—some with long-term back pain and some without—to measure their stability during bending and twisting motions. The goal was to better understand the physical effects o…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:53 UTC
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Arm position matters: study reveals best way to see veins on ultrasound
Knowledge-focused CompletedThis study looked at 50 healthy adults to see if changing arm position makes veins in the armpit and collarbone area easier to see on ultrasound. Researchers measured the visible surface of these veins with the arm by the side versus raised and rotated. The goal is to help doctor…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:53 UTC
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Blood clot marker study: are the numbers stable month to month?
Knowledge-focused CompletedThis study looked at whether two blood markers—nucleosomes and free DNA—stay consistent over time in healthy people and in patients who have had a blood clot (venous thromboembolism). Researchers took monthly blood samples from 15 healthy volunteers and 15 patients for six months…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:53 UTC
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Healthy volunteers help unravel movement complexity
Knowledge-focused CompletedThis study looked at how healthy adults perform simple tapping tasks to measure the complexity of their movements. Researchers used special math tools to analyze these movements, aiming to find patterns that might one day help diagnose or treat movement disorders. The study invol…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:53 UTC
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Heart clot strokes leave unique brain signatures, study finds
Knowledge-focused CompletedThis study looked at brain MRI scans of 122 stroke patients to see if those with a clot in the heart (intracardiac thrombus) had different patterns of brain damage compared to those with a common heart rhythm problem (atrial fibrillation). Researchers examined the location, size,…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:53 UTC
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AI and cap team up to spot hidden colon polyps
Knowledge-focused CompletedThis study compared three ways to find precancerous colon polyps during colonoscopy: using an AI system alone, a special cap (Endocuff) alone, or both together. About 481 adults undergoing screening colonoscopy took part. The goal was to see if the combination finds more polyps t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:53 UTC
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ICU breathing machines may leave lasting mental fog
Knowledge-focused CompletedThis study followed 125 ICU patients who needed a breathing tube and sedation for at least 48 hours. Researchers tested their memory and attention 4 months after leaving the hospital to see how many had lasting cognitive problems. The goal was to better understand the mental afte…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:52 UTC
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Robot surgery vs. open surgery: which is cheaper for prostate cancer?
Knowledge-focused CompletedThis study looked at the total cost of care over 5 years for men with localized prostate cancer who had either robot-assisted surgery or open surgery. Researchers tracked all medical expenses from the surgery itself to follow-up care. The goal was to see which approach is more co…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:52 UTC
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Study tests accuracy of common blood clot test in hospital patients
Knowledge-focused CompletedThis study looked at how well the Wells score, a tool doctors use to predict deep vein thrombosis (blood clots), works for patients already in the hospital. Researchers compared the score's accuracy between patients who were and were not on blood thinners. The goal was to improve…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:52 UTC
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Brain scans reveal hidden damage in pregnancy-related immune disorder
Knowledge-focused CompletedThis study followed 40 women with obstetric antiphospholipid syndrome, a condition that can cause pregnancy complications. Researchers used MRI scans to see if the brain's white matter gets worse over time. The goal was to understand long-term brain health, not to test a treatmen…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:52 UTC
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Ultrasound showdown: which vein route wins for catheter placement?
Knowledge-focused CompletedThis study tested two methods for inserting a central venous catheter (a large IV in the chest) using continuous ultrasound guidance: one through the subclavian vein and one through the axillary vein. 132 adults who needed a central line took part. The goal was to see which techn…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:52 UTC
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Spleen trauma care under the microscope: french study reveals treatment patterns
Knowledge-focused CompletedThis study tracked 93 people hospitalized for spleen injuries caused by trauma (like car crashes or falls) in southern France. Researchers wanted to see how doctors treat these injuries based on severity, and what happens to patients in terms of deaths, complications, and how lon…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:52 UTC
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Blood clot study hunts hidden mutations in older adults
Knowledge-focused CompletedThis study looked for certain genetic mutations in blood cells of 150 people over 50 who had a history of venous thromboembolism (blood clots). The goal was to see how common these mutations are in this group. No treatment was given; the study only observed and analyzed DNA sampl…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:52 UTC
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Gut bacteria clues in early arthritis
Knowledge-focused CompletedThis study looked at the gut bacteria of 55 people—some newly diagnosed with rheumatoid arthritis and some without the disease. Researchers wanted to see if certain bacteria are more common in arthritis patients. The goal was to learn more about how gut health might relate to art…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:52 UTC
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Racial bias in the ER: study reveals unequal pain prescriptions for sickle cell patients
Knowledge-focused CompletedThis study asked over 1,000 emergency doctors in Europe what they would prescribe for a patient with severe belly pain. The patient's race was changed in the story to see if it affected the doctor's choice of pain medicine. The goal was to understand if racial bias plays a role i…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:52 UTC
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Pandemic's hidden toll: ICU caregivers face PTSD and burnout
Knowledge-focused CompletedThis study looked at how working in intensive care units during the COVID-19 outbreak affected the mental health of doctors, nurses, and other caregivers. Over 700 staff members completed surveys about post-traumatic stress disorder (PTSD), anxiety, depression, and burnout. The g…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:52 UTC
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Scientists peek inside pregnancy cells to predict complications
Knowledge-focused CompletedThis study looked at how two natural cell processes — autophagy (cell cleanup) and apoptosis (cell death) — change during pregnancy. Researchers measured these in 97 pregnant women, including those at risk for complications, to understand how their balance might affect pregnancy …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:51 UTC
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Life after prostate cancer: how do patients really feel?
Knowledge-focused CompletedThis study looked at how prostate cancer patients feel about their quality of life three years after diagnosis, when they are expected to be back to normal. Researchers compared 900 patients to people of the same age without cancer. The goal was to understand the long-term impact…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:51 UTC
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Could a common virus and low vitamin d trigger MS?
Knowledge-focused CompletedThis study looked at 110 people with radiologically isolated syndrome (RIS) — a condition where brain scans show signs that may lead to multiple sclerosis (MS). Researchers measured Epstein-Barr virus antibodies and vitamin D levels in blood samples to see if these factors help p…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:51 UTC
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Scientists uncover key immune differences in preeclampsia
Knowledge-focused CompletedThis study looked at how certain immune cells (neutrophils) release web-like structures called NETs in pregnant women. Researchers compared samples from 26 women with normal pregnancies and those with preeclampsia, a serious blood pressure condition. The goal was to understand th…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:51 UTC
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Pandemic's hidden toll: nursing home staff face high rates of PTSD
Knowledge-focused CompletedThis study looked at how the COVID-19 pandemic impacted the mental health of 501 nursing home workers in Occitanie, France. Researchers measured rates of post-traumatic stress disorder (PTSD), depression, and burnout using standard questionnaires. The goal was to understand how c…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:51 UTC
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Which workout heals the heart better after a heart attack?
Knowledge-focused CompletedThis study looked at two different exercise programs for people who had a heart attack. One program used steady, moderate exercise, and the other used short bursts of high-intensity exercise. The goal was to see which program better improved heart function, measured by a special …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:51 UTC
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Ultrasound may make blood draws easier and less painful
Knowledge-focused CompletedThis study tested whether using ultrasound to guide a needle makes drawing blood from the radial artery (in the wrist) easier and less painful. 74 adults who needed an arterial blood sample took part. Researchers measured how often the first try succeeded, the number of attempts,…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:50 UTC
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Sit up straight? study reveals how chair type changes your spine
Knowledge-focused CompletedThis study measured how the lower spine and pelvis align when sitting in a straight chair versus an ergonomic chair. Researchers compared 20 people with and without chronic back pain to see if chair type makes a difference. The goal was to understand posture, not to test a treatm…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:50 UTC
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Mental health risks explored in women with clotting disorder
Knowledge-focused CompletedThis study looked at how common psychiatric conditions like depression, anxiety, and substance use are in women with antiphospholipid syndrome (a blood clotting disorder) compared to those with other clotting issues. Researchers surveyed over 1,500 women about their mental health…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:50 UTC
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France's ICU surge: a blueprint for crisis care?
Knowledge-focused CompletedThis study looked back at how French hospitals created more ICU beds and found extra doctors and nurses during the COVID-19 outbreak. It included nearly 10,000 hospitals across France. The goal was to understand where the new beds came from and how staff were reassigned to handle…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:50 UTC
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Study reveals key factors for getting antibiotic dosing right in ICU
Knowledge-focused CompletedThis study looked at 156 critically ill patients to find out what factors help achieve the right levels of beta-lactam antibiotics in the blood. Researchers collected patient data and used special monitoring to see why some patients reached target levels and others did not. The g…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:50 UTC
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Do higher antibiotic doses work better in sepsis? new study investigates
Knowledge-focused CompletedThis study looked at whether giving higher doses of two common antibiotics (amikacin and gentamicin) helps critically ill patients with severe sepsis reach target drug levels in their blood. Researchers studied 63 ICU patients to see if the higher doses were effective. The goal w…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:50 UTC
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New blood pressure test could help kidney patients
Knowledge-focused CompletedThis study tested a new way to measure blood pressure in 90 people with severe kidney failure. The new method uses a different timing technique to see if it works as well as the standard arm-cuff method. The goal was to find a more accurate way to measure blood pressure in patien…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:50 UTC
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Vitamin d gene clues in ALS: 800-Person study completed
Knowledge-focused CompletedThis study compared 400 people with ALS (a nerve disease) and 400 healthy people to see if differences in vitamin D-related genes are linked to the disease. Researchers analyzed DNA samples for specific gene variations. The goal was to better understand the disease, not to test a…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:50 UTC
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Magnetic needle guide tested on dummy for safer IV insertion
Knowledge-focused CompletedThis study compared a new magnetic device (Needle-pilot) to standard ultrasound for placing a central line in the subclavian vein. 51 doctors practiced on a mannequin torso. The goal was to see if the device made the procedure faster or easier. This was a simulation, not a real p…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:49 UTC
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ER violence under the microscope: counting aggressive incidents in the emergency department
Knowledge-focused CompletedThis study aimed to count how often violent events happen in the emergency department at Nîmes University Hospital. Researchers observed 30 patients and staff to track aggressive incidents based on a pre-defined list. The goal was simply to measure the problem, not to test a trea…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:49 UTC
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ICU dialysis study seeks safest fluid removal speed
Knowledge-focused CompletedThis study looked at 39 intensive care patients with acute kidney failure who needed dialysis to remove extra fluid. Researchers tested three different fluid removal rates to see which one caused the fewest dangerous drops in blood pressure while still effectively managing fluid …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 03:49 UTC
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ER ultrasound study: can two docs agree on diaphragm measurements?
Knowledge-focused CompletedThis study looked at whether two different doctors can reliably measure diaphragm movement using ultrasound in patients with severe breathing problems in the emergency room. 26 adults with acute respiratory distress took part. The goal was to see if the measurements were consiste…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Vaginal bacteria linked to birth tears?
Knowledge-focused CompletedThis study looked at whether pregnant women with certain types of vaginal bacteria are more likely to have tears or lesions during childbirth. Researchers checked the vaginal flora of 1,100 women and compared those with abnormal bacteria to those with normal bacteria. The goal wa…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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COVID-19 blood clot mystery: new study reveals clotting risks in severe cases
Knowledge-focused CompletedThis study examined blood clotting issues in 175 hospitalized COVID-19 patients. Researchers measured how well the blood forms clots (thrombin generation) to see if these tests could predict survival. The goal was to better understand why severe COVID-19 causes dangerous clotting…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Rapid tests reveal hidden infections in detention
Knowledge-focused CompletedThis study looked at how many people held in the Nîmes administrative detention center have HIV, hepatitis B, or hepatitis C. Researchers used rapid tests to get results quickly, since many detainees leave before standard lab results come back. The goal was to find out how common…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Rare stroke cause under the microscope: new study details calcified embolism
Knowledge-focused CompletedThis study looked at 79 patients with calcified cerebral embolism, a rare and often missed cause of stroke. Researchers used CT scans to describe the size, location, and other features of these calcified blockages. The goal was to better understand this condition and help doctors…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Kids' pill-taking habits under the microscope: new study tracks antibiotic use after hospital discharge
Knowledge-focused CompletedThis study looked at how well children under 16 take their anti-infective medicines after being discharged from the hospital. Researchers followed 75 kids for one month to see if they took their prescriptions correctly. The goal is to understand the problem of poor compliance, wh…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC
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New questionnaire could help predict falls in seniors
Knowledge-focused CompletedThis study looked at a questionnaire called the Balance and Daily Life (EVQ) to see if it is a reliable way to measure balance and fall risk in frail older adults. Researchers tested 140 people aged 65 and older who were in a hospital rehabilitation unit. The goal was to see if t…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC
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Which mattress wins? study tests pressure relief for bedridden patients
Knowledge-focused CompletedThis study tested two special mattresses (Nimbus 3 and Summit) to see which one better prevents bedsores in people who are stuck in bed. 31 bedridden adults with some mobility were measured for pressure on their bottom and back. The goal was to find out which mattress spreads pre…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC
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Ultrasound beats touch for tough blood draws?
Knowledge-focused CompletedThis study tested whether using ultrasound to locate the wrist artery makes drawing blood easier for patients whose arteries are hard to feel. 74 adults who needed an arterial blood sample but had weak pulses or failed previous attempts were split into two groups: one using ultra…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC
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New home health tracker tested for Post-Surgery monitoring
Knowledge-focused CompletedThis study tested a medical device that lets patients record their blood pressure, heart rate, and oxygen levels at home after outpatient surgery and send the data to their doctors. 30 adults having certain types of surgery used the device to see if it was easy to use and accurat…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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Can a tailored workout boost heart health in obesity and diabetes?
Knowledge-focused CompletedThis study looked at how an 8-week personalized exercise program affects heart and blood vessel function in 59 men with obesity or type 2 diabetes. Participants were compared to healthy volunteers, both trained and untrained. The goal was to see if exercise can improve cardiovasc…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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Abdominal infection study seeks to improve emergency care
Knowledge-focused CompletedThis study observed 200 adults treated in the emergency room for abdominal infections that required surgery. Researchers wanted to see how delays in diagnosis and treatment affect recovery. The goal is to find ways to improve care and reduce complications.
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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Blood protein clues may predict pregnancy dangers
Knowledge-focused CompletedThis study looked at certain proteins (histones and HMGB1) in the blood of 115 pregnant women, some with complications like pre-eclampsia and some with healthy pregnancies. The goal was to see if these proteins could serve as early markers for placental problems. The research did…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Robot vs. no robot: which trains surgeons better?
Knowledge-focused CompletedThis study tested whether using a robot during training helps surgical interns learn laparoscopy faster. 34 interns were split into two groups: one trained with robotic assistance and one without. They were timed while performing a kidney removal (nephrectomy) on a pig. The goal …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Tiny study reveals bleeding risk in stroke patients with 'fragile vessel' brain condition
Knowledge-focused CompletedThis study looked back at 15 stroke patients who had a condition called cerebral amyloid angiopathy (CAA), which makes blood vessels in the brain fragile and prone to bleeding. All received a clot-busting drug (IV thrombolysis) for their stroke. Researchers checked CT scans 24 ho…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Scientists measure walking imbalances in amputees to improve rehab
Knowledge-focused CompletedThis study looked at 130 adults with leg amputations (below or above the knee) to measure how their walking balance differs between their sound and prosthetic limbs. Researchers used special pressure-sensing platforms to track foot placement and stability during a short walk. The…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Colostomy patients share their bathroom habits in major survey
Knowledge-focused CompletedThis study surveyed over 1,100 adults with a colostomy to find out how many use colon irrigation (a way to rinse the bowel) and how it affects their daily life. Researchers compared quality of life between those who use irrigation and those who don't, and explored why some people…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Why stroke patients avoid using their weak arm: new insights
Knowledge-focused CompletedThis study looked at why some stroke survivors can move their affected arm but choose not to use it, a condition called non-use. Researchers tested 53 people to see how the effort needed (force) and the accuracy required (precision) affect arm use. The goal is to better understan…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Tiny study aims to unlock how plasma filters work in rare nerve disease
Knowledge-focused CompletedThis study looked at two ways to filter the blood (plasmapheresis) in people with CIDP, a rare nerve disease that causes weakness. The goal was to see how each method affects certain immune cells. Eight adults took part, and the study was completed, but it was very early-stage an…
Phase: EARLY_PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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New french tool helps understand how patients perceive their back pain
Knowledge-focused CompletedThis study tested a French version of a questionnaire called the FreBAQ, which measures how people with chronic low back pain perceive their back. The goal was to see if the French version works as well as versions in other languages. 150 adults with and without chronic low back …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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New test may improve antibiotic choice for diabetic foot wounds
Knowledge-focused CompletedThis study looked at a new lab test called Antibiofilmogramme® for people with diabetic foot infections caused by Staphylococcus aureus bacteria. Researchers wanted to see if the test could help doctors pick the right antibiotic. The study involved 33 adults and did not change th…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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New study explores whether a simple talk can improve life after breast cancer
Knowledge-focused CompletedThis study involved 50 women who finished treatment for early-stage breast cancer. Researchers wanted to see if a special 'remission' consultation could improve their quality of life over the next year. Participants filled out questionnaires about their well-being and body image …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC
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Stockings under pressure: new study reveals how compression affects veins
Knowledge-focused CompletedThis study looked at how compression stockings of different strengths change the pressure on the leg and the size of veins in people with chronic venous insufficiency. Researchers measured vein diameter and leg pressure in 111 participants (patients and healthy volunteers) while …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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Shock drug dose linked to death risk in ICU patients
Knowledge-focused CompletedThis study examined 100 critically ill patients with circulatory shock in the ICU who received norepinephrine, a drug that raises blood pressure. Researchers wanted to see if a certain dose of norepinephrine was linked to a higher risk of death within 5 days. They also looked at …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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Study reveals Post-Birth diabetes risk in moms with gestational diabetes
Knowledge-focused CompletedThis study looked at 500 women who had gestational diabetes during pregnancy. It checked how many had abnormal blood sugar (like type 2 diabetes or prediabetes) 4 to 12 weeks after giving birth. The goal was to see if the timing of their gestational diabetes diagnosis (before or …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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Botox for stroke spasticity: scientists track nerve signals to predict when treatment fades
Knowledge-focused CompletedThis study looked at 40 stroke patients with arm muscle stiffness (spasticity) who received botulinum toxin (Botox) injections. Researchers measured tiny electrical signals in the muscle to see how they change over time and whether they can predict when the treatment starts weari…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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Brain scan study aims to help doctors tell apart two common small vessel diseases
Knowledge-focused CompletedThis study looked at brain scans from 315 people with two different types of small vessel disease: cerebral amyloid angiopathy (CAA) and hypertensive arteriopathy (HA). Researchers measured white matter changes around the brain's ventricles to see if the pattern of these changes …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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French hospitals study gunshot wounds in ICU
Knowledge-focused CompletedThis study looked back at the medical records of 120 people who were treated in French intensive care units (ICUs) for gunshot wounds between 2015 and 2021. The goal was to understand how often people died within 28 days and what types of organ damage occurred. The researchers al…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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New sensor could Fine-Tune electrical stimulation for stroke patients
Knowledge-focused CompletedThis study tested a small wearable sensor (FOX HiKoB) to see how well it measures foot movement in people who have had a stroke and have trouble lifting their front foot (foot drop). The sensor was compared to a standard motion-capture system. The goal was to see if the sensor co…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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Immune clues could predict diabetes risk before it starts
Knowledge-focused CompletedThis study examined 158 adults aged 55 to 69 to see if certain immune system markers are linked to insulin resistance, a condition that can lead to diabetes. Researchers measured blood cells, gut bacteria, and other health indicators to find patterns that might help identify at-r…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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Brain scans may reveal clues to mysterious movement disorder
Knowledge-focused CompletedThis study looked at 20 people with a first episode of motor conversion disorder, a condition where psychological stress causes physical symptoms like paralysis or weakness. Researchers used PET scans to check for unusual brain activity at the start of symptoms. They then followe…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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Brain scan study aims to predict drug success in recurrent glioblastoma
Knowledge-focused CompletedThis study looked at whether special brain scans (PET and CT perfusion) can predict how well the drug bevacizumab works in people with a returning brain tumor called glioblastoma. Fourteen patients were enrolled. The goal was to see if these scans could tell doctors early on who …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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New score may predict septic shock deaths
Knowledge-focused CompletedThis study tested a new scoring system that uses routine blood tests to predict the risk of death within one month for patients with septic shock in the intensive care unit. Researchers enrolled 780 adults with severe sepsis and organ failure. The goal was to see how well the sco…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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DNA clues in the blood: a new way to study cancer surgery?
Knowledge-focused CompletedThis study looked at how DNA from tumors changes in the blood before, during, and after cancer surgery. Thirty adults with breast, prostate, or colon cancer had blood samples taken to measure these DNA levels. The goal was to understand the natural changes, not to test a treatmen…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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New bone scanner put to the test against gold standard
Knowledge-focused CompletedThis study checked if a new bone density scanner (Stratos DR) gives the same results as a trusted older model (Discovery A) for measuring body fat and muscle. Fifty adults who needed a bone scan took part. The goal was to see if the new machine is accurate and reliable enough for…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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Fasting before surgery: harmless or risky?
Knowledge-focused CompletedThis study looked at whether not eating before surgery (preoperative fasting) causes low blood volume. Researchers used heart ultrasound to measure blood volume changes in 100 patients scheduled for gynecological or abdominal surgery. The goal was to see if fasting leads to a dro…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 20, 2026 11:54 UTC
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Stroke gait study aims to perfect foot stimulation timing
Knowledge-focused CompletedThis study observed 20 stroke patients with leg weakness to understand the timing of their steps. Researchers compared signals from a foot switch and a motion sensor to standard walking measurements. The goal was to use this data to better trigger electrical stimulation that help…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC
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Antifungal dosing study in septic shock patients completed
Knowledge-focused CompletedThis study looked at how the body processes antifungal drugs (echinocandins) in 24 adults with septic shock caused by a serious abdominal infection (peritonitis). The goal was to measure drug levels in the blood to help doctors choose the right dose. It did not test a new treatme…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC
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Robots take on throat cancer: study checks if they get it all
Knowledge-focused CompletedThis study observed 54 people with early-stage laryngeal cancer who had robot-assisted surgery to remove their tumors. The main goal was to see how often the surgery left healthy tissue around the cancer (clear margins). Researchers also tracked surgery time and complications. Th…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 19, 2026 11:59 UTC
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Can less fluid help septic shock patients? new study explores
Knowledge-focused CompletedThis study tested whether carefully limiting fluids given for maintenance, drug dilution, and nutrition (not for emergency resuscitation) could reduce fluid overload in intensive care patients with septic shock. Fifty adults participated, and researchers measured their fluid bala…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 19, 2026 11:48 UTC
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Pharmacist intervention boosts pneumonia shots in hospital patients
Knowledge-focused CompletedThis study looked at whether a clinical pharmacist could help increase pneumococcal vaccination rates in patients at high risk for infection when they leave the hospital. Researchers tracked how many vaccine plans were given to 167 adult patients. The goal was to see if a pharmac…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 19, 2026 11:47 UTC
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Does poverty predict late breast cancer diagnosis?
Knowledge-focused CompletedThis completed study looked at 684 people with breast cancer to see if those with unstable living conditions (social fragility) are more likely to be diagnosed at a later, harder-to-treat stage. Researchers compared early-stage (good prognosis) and late-stage (poor prognosis) cas…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 12:13 UTC
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Immune cell study aims to unlock secrets of childhood rash disease
Knowledge-focused CompletedThis study examined whether children with Henoch Schönlein Purpura (HSP) have problems with a type of immune cell called regulatory T cells. Researchers compared blood samples from 100 children with HSP to healthy controls. The goal was to better understand the disease, not to te…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 12:13 UTC
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Healthy volunteers help doctors understand vein behavior during breathing
Knowledge-focused CompletedThis study looked at 52 healthy adults to see how much the inferior vena cava (a large vein) collapses when they breathe. Researchers used ultrasound to measure the vein's diameter during inhaling and exhaling. The goal was to find a breathing-related measurement that best predic…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 12:12 UTC
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Nose bacteria linked to foot infections in diabetics
Knowledge-focused CompletedThis study looked at whether the same staph bacteria found in the nose can also infect foot sores in people with diabetes. Researchers compared the genetic fingerprints of bacteria from both places in 278 patients. The goal was to understand the risk and improve detection, not to…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 12:12 UTC
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French ICUs see more severe cases yet deaths drop
Knowledge-focused CompletedThis study looked at over 1.5 million adults admitted to French intensive care units (ICUs) between 2013 and 2019. Researchers wanted to understand trends in patient numbers, how sick they were, how long they stayed, and death rates. They found that while patients were more criti…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 12:10 UTC
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Scientists probe immune overreaction in severe COVID-19 to find new clues
Knowledge-focused CompletedThis study looked at 120 hospitalized COVID-19 patients with severe breathing problems to understand how their immune systems were reacting. Researchers measured many immune markers in the blood to see if a specific immune pattern could predict who might die. The goal was to find…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 12:09 UTC
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New device aims to cut spine screw errors in half
Knowledge-focused CompletedThis study tested a new device called PYTHEAS ODYSSEE that helps surgeons place screws in the spine more accurately. Poorly placed screws can cause serious problems like bleeding or paralysis. The device uses a patient's CT scan to plan screw placement and then guides the surgeon…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 12:07 UTC
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Can a simple distraction change how people with back pain walk?
Knowledge-focused CompletedThis pilot study looked at how people with chronic low back pain walk and whether a distraction task could change their walking pattern and reduce pain. 16 adults with long-term back pain walked at their normal speed and a faster speed, with and without a distraction. The goal wa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 12:07 UTC
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DNA in blood may reveal pregnancy problems early
Knowledge-focused CompletedThis study measured levels of free DNA and nucleosomes in the blood of 137 women to see if these markers differ between healthy pregnancies and those with complications like preeclampsia or blood clots. The goal was to understand how these substances relate to placental problems.…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 12:02 UTC
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Scientists compare three methods to measure pelvic movement in healthy volunteers
Knowledge-focused CompletedThis study looked at 120 healthy volunteers to see how well three different methods (clinical observation, photography, and a special imaging system called EOS) measure pelvic area extension. The goal was to describe the range of motion for four common pelvic balance types. The s…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 12:02 UTC
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Could a Pre-Surgery blood vessel block boost colon healing?
Knowledge-focused CompletedThis small pilot study tested whether blocking the inferior mesenteric artery with tiny particles 3-4 weeks before rectal or sigmoid colon cancer surgery helps the colon develop better blood flow. Ten adults with rectal or sigmoid cancer took part. The goal was to see if this pre…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 12:00 UTC
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CRPS Patients' brain imagery under the microscope
Knowledge-focused CompletedThis study looked at whether people with Complex Regional Pain Syndrome (CRPS) have trouble imagining movements in their mind. Researchers compared 129 adults—some with CRPS, some with other muscle pain, and some healthy—using a questionnaire that measures motor imagery skills. T…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 11:59 UTC
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Blood marker may foretell COVID-19 survival
Knowledge-focused CompletedThis study looked at whether a blood test marker called NEU-SFL, which reflects immune cell activity, can help predict the risk of death in people hospitalized with COVID-19 in 2021. Researchers compared NEU-SFL levels between those who survived and those who did not. The goal wa…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 18, 2026 11:59 UTC
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Personalized diet advice tested for MS patients
Knowledge-focused CompletedThis study looked at whether personalized dietary advice from a dietitian helps people with multiple sclerosis (MS) increase their calcium intake compared to just receiving a standard information sheet. A total of 182 MS patients who could walk and had never had a diet consultati…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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New blood test tech helps ICU patients get the right antibiotic faster
Knowledge-focused CompletedThis study looked at whether using three new lab technologies could help doctors choose the best antibiotic faster for ICU patients with a serious bloodstream infection. Researchers compared how often patients got the right antibiotic within 24 hours before and after the new tool…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Global survey reveals antibiotic dosing practices in ICUs
Knowledge-focused CompletedThis study collected information from 964 critically ill patients in intensive care units across multiple countries to understand how doctors prescribe and monitor aminoglycoside antibiotics (tobramycin, amikacin, or gentamicin). The goal was to describe current practices and ide…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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Blood thinner dilemma: study probes deadly delays in hip fracture surgery for seniors
Knowledge-focused CompletedThis study looked back at 610 elderly patients on blood thinners (DOACs) who needed hip fracture surgery. Doctors often delay surgery to let the drug wear off, which can increase the risk of death. The goal was to understand current practices and outcomes to help design a future …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC
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New sexuality surveys tested for women with bladder or pelvic issues
Knowledge-focused CompletedThis study tested two French-language questionnaires about sexuality in 298 women who had surgery for pelvic organ prolapse, urinary incontinence, or fecal incontinence. The goal was to see if these new tools accurately measure sexual function compared to an existing questionnair…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC
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New study hopes to predict dangerous pregnancy complication with simple blood test
Knowledge-focused CompletedThis study looked at 513 pregnant women with antiphospholipid antibody syndrome (oAPS) to see if measuring a protein called ADAMTS13 early in pregnancy could help predict preeclampsia, a serious condition involving high blood pressure. Researchers measured ADAMTS13 levels in stor…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:40 UTC
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New tests could spot dangerous fungus earlier in ICU patients
Knowledge-focused CompletedThis study looked at 422 ICU patients to see if a combination of tests could detect Candida (a fungus) infections earlier and more accurately. The tests included blood antibody and antigen tests, DNA detection, and checking samples from multiple body sites. The goal was to improv…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 12, 2026 13:39 UTC