Tight stockings under the microscope: new data on vein pressure
NCT ID NCT01558024
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how compression stockings of different strengths change the size and pressure of leg veins in people with chronic venous insufficiency and healthy volunteers. Researchers measured vein diameter and leg pressure while participants stood, sat, or lay down. The goal was to better understand how stockings work, not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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111 people
The number who actually took part.
- Start date
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Jul 2014
- Finished
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Mar 2016
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The participant must have given his/her informed and signed consent * The participant must be insured or beneficiary of a health insurance plan Inclusion criteria for patients in the venous insufficiency group: * CEAP (Clinical-Etiology-Anatomy-Pathophysiology) Classification : C1S, C3 or C5 Inclusion criteria for healthy volunteers * general good health * subgroups including: * sedentary volunteers (\< 2hours of physical activity per week) * active volunteers (between 2 and 6 hours of physical activity per week) * athletic volunteers (over 6 hours of physical activity per week for at least 1 year) Exclusion Criteria: * The participant is participating in another study, except the "volumetric" counterpart to the present study * The participant is in an exclusion period determined by a previous study * The participant is under judicial protection, under tutorship or curatorship * The participant refuses to sign the consent * It is impossible to correctly inform the participant * The participant is pregnant, parturient, or breastfeeding * Arterial vascular disease, heart, lymph, renal, hepatic, oncologic, metabolic or endocrine or any other condition that may cause or exaggerate edema Exclusion criteria for healthy volunteers: * Risk for abnormal bleeding (hemophilia, anticoagulation or antiplatelet) * Taking diuretics or corticoids
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU de Montpellier - Hôpital Saint-Eloi
Montpellier, 34295, France
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CHU de Nîmes - Hôpital Universitaire Carémeau
Nîmes, 30029, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a Lab-Grown vein with a Built-In valve fix damaged leg veins?
- Could leg vein disease weaken breathing and strength?
- Blood thinners after vein laser: which works best to stop dangerous clots?
- Scientists track varicose veins from start to worse
- New method aims to make compression stockings easier to wear